Hemolytic Anemia Flashcards

1
Q

What are some drugs that are implicated in warm autoimmune hemolytic anemia?

A

Methyldopa, quinidine, quinine, Sulfonamides, PCNs/cephalosporins.

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2
Q

What chemo drugs are associated with WAIHA?

A

Purine analogs-Cladribine, Pentostatin, and Fludarabine.

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3
Q

What are the treatment options for primary CAD?

A

You can use Rituximab alone, in combination with alpha interferon, BR, bortezomib based therapy, ibrutinib, and plasmapheresis in severe cases. Sutimlimab can also be used.

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4
Q

What antigen is involved in PCH?

A

The big P antigen

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5
Q

What antigen is involved in mycoplasma associated cold agglutinin disease?

A

The big I antigen

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6
Q

What is the mechanism of action of Sutimlimab in CAD?

A

It is a C1 esterase inhibitor

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