micro V last minute Flashcards
form of coccidioodies immitis
dimorphic - mold in environement, yeast in tissue
form of cryptococcus neoforms
encapsulated yeast all the time
What does coccidiomomycosis look ilke in tissue
spherule
What does coccidiomycocis start as
mild to moderate flu like symptoms
What is the leading form of fungal menigitis
cryptococcus
where is crytococcosis found
throughtout the world
what is cryptococcosis associated with
pigeon shit
pulmonary disease of cryptococcus
flu like
little sputum production
little lung damge
what is common in AIDS patients with cryptococcosis
replase, require suppressive therapy
how do you treat menigitis from cryptococcis
long term treatment with amphotericine B and 5-fluortosine
who gets rhinocerebral zignmycosis
diabetic patents
how do you diagnose zygomycoses
broad aseptate hyphae branching at right angles
rhinocerebral zygomycosis symptoms
start as cold
go to facial/periorbal edema,
entamoeba histolytica
brain abscesses
plasmodium falciparum
cerebral malaria
protozoa
opportunisitic amoeba
PAM
splooshing water because of naegleia
how do you confirm PAM
observe trophozoites in CSF
GAE
caused by acanthamoba and balamuthia
how is GAE in relation to be PAM
develops slower
what happens in GAE
amoeba invade brain, result in slow developing ulcerative lesion
acanthameoba kertitis
chronic infectino of cornea
assocaited with contact lens
What happens to HIV patients with toxoplasmosis
get encephalisits with ring enhancing lesion
How do you test mom for toxoplasmsosis
IgM or rising IgG
how do you test neonate for toxoplamosis
IgM
how do you treat neonate with toxoplasmosis
treat for a year
what kind of lesion does cysticerus creat
space filling lesion
how do you diagnose taenia solium
CT, MRI, seology
toxocara canis and t. cati
granulamotus lesions develop
eggs not in human poop
what type of infection is most common in visceral larval migrans
eye infectino
how do you diagnose visceral larval migrans
eosinophilia
Bunyaviruses
lacrosse
Reoviruses
colorado tick fever
arenavirsues
lymphocytis choriomegitis
What is the major cause of arbovirus encephalitis in the US
STL
what is the resvoroir for JEV
birds and livestock
resevoirs for togaviruses
horses, rodents, birds
who gets EEE most often
kids
symptoms of EEE
sudden onset of fever, general muscle pains, headache
resovoirs of lacrosse virus
chipmunks and tree squirrels
how do rabies travel
enter perihperal nerves into CNS< then proliferates and sends back out to the CNS
how do you confirm raabies
negri bodies
how is LCMV spread
inhaling aerolized particles of urine, feces, salvia of house mouse
what is the LCMV disaes like
biphagic - 1 week, time off, then gets work
how do you treat LCMV
hospitalization
transcient bactermic pattern
an upspike, then goes away
what causes septic shock more often
gram neg
what is the production of pyrogenic exotoxins assocaited with
streptococcal toxic shock syndrome
what do pyrogenic exotoxins do
stimulate T cells by binding to class II major histcompatiblity complex
v. vulnificus
hemorrhagic skin lesions in a septic person who recently ate raw osyters
what can sometimes be the only symprtom of endocarditis
splenomegaly
how do you treat v. streptococci
penicillin
vanco if resistant
major critia for endocarditis
postive blood culture
postive echocardigrame, valve reguritation
how does epstein barr virus enter the body
C3d component of complement system
where does epstein barr virus replicate
epithelial and b cells
LMP1 is a homologue to what
CD40
LMP2
increased growth of B cells
EBNA1
transaction of EBV transforming genes
inhibition of apoptosis
pathogensis of mono
immune targeting of infected B cells
antibodies to EV demonstrate what
IgM to viral capsid antigen
DOwney celsl
present in mono
atypical T cells
how do you treat burkitts lymphoma
chemo
cofactors for burkitts lymphoma
chronic malaria
immune suppression
reed sterberg cell
hodgkins
has 2 or more nuclei
symptoms of nasopharyngeal carcinoma
facial pain
fullness in sinues and throat
hearing loss
cofactors o nasopharygeal carcinoma
genetics
diet
where does CMV replication take place
mucosal epitherlim
virum
how is CMV tranmitted
salivia reast milk urine fomites sex
gancyclovir
IV or oral. converted to viral polymerase inhibitory
valganciclovir
converted to ganclycovir in body. oral
cidofovir
converted to viral polymerase inhibitor by cellular enzymes. more toxic IV
foscarnet
direct inhibitor of CMV polyermase. renal toxic IV
symptoms of cytomegalic inclusion body disease
hepatosplenomegaly
jaudince
petechiae
how do you prevent cytomegalic inclusion disease
handwashing
avoid sharing drinks
symptoms of CMV in immunosppressed people
spiking fever
presetation of myocarditis
SOB
exervise intolerance
fatique
mmumps genome
-ssRNA
histology of kaposi’s sarcoma
spindle morphology
how do you transmit HHV8
sex
needles
HHV-8 associated disaes
castlemans
primary effusion lymphoma
how do you terat KS
chemo
radation
sx
presentatino of ATL
lymphadenopathy
hepatosplenomegaly
hypercalcemia
skin infilation
how do you transmit HTLV
nursing
blood transufion
sex
how do you treat african sleeping skickness
DFMO
resevor for lesmaniaisis
dog, rats
where are parasites in visceral lieshmanisis found
macrophages of liver, spleen, bone marrow
lesimanissi symptoms
fever, weight loss, hepatosplenomegaly, wasting appearance
resosor for babesisa
rodent cattle
how do you terat babesis
atovaquone
z pak
how do you diangose filiarisi
microfiliari in blood smear
how do yo utreat filarisi
steroids
how do you diagnose schistoma
eggs in feces or urine