micro exam 4 last minute Flashcards
Kiolocytes are associated with what?
HPV
How do you treat syphilis if it is resistant to penicillin?
doxycycline
What are the chlamydia serovars?
trachoma
LGV
Syphilius ulcer
firm
painless
sharply demarcated
Herpes ulcer
bleeds
tender
multiple lesions
Chancriod ulcer
pustule
purulent, bleed easy
soft
tender
LGV ulcer
usually one
evelated, round or oval
Donovanosis ulcer
elevated
red and velverty, bleeds easily
What is associated with reiter syndrome
chlymidia
reiter syndrome triad
urethritis, conjunctivitis, polyartheritis
symptoms of LGV besides the papule
inguinal lymphadenopathy
buboes
How do you treat chlyamdia
doxycycline or macrolides
Which gonorrhea virulence factors undergo antigenic variation
opa
por
pilin
LOS
disseminated infection going into the joints is associated with
n. gonorrhoeae
How do you treat gonorrhea
ceftriaxone plus doxycycline or z pak
What do nontreponemal tests look for
cardiolipin
What do treponemal tests look for
t. pallidum
FTA-ABS antibody
What should you test your patient with urethritis for
gonorrhea and chlamydia
How do you treat M/. genitalium
azithromycin
How do you terat m. hominis
doxycyline
When is ureaplasma not typically found
before puberty
How do you treat ureaplasma
doxycylline
how do you treat reccurent non-gonococcal urethritis in men
azithromycin or quinolones
How do you diagnose ducrey
slow growth on chocolate agar
chocolate agar with vanocmycin
How do you treat ducrei
macrolide
Hysterectomy with removal of cervix is associated with whiat
increase fragilis
increase e coli and enteroccus
What is amsel critieria is used for
BV
What are major criteria for tooxic shock
hyptension
synope
sunburn that peels
What are the important proteins in HIV
gp120 gp41 pol p17 p24
What does gp120 bind to
CD4
function of gp41
mediates fusion between the viral envelop and plasma membrane
pol gene
virally encoded enzyme
acute HIV symptoms are similiar to what disease
mono
What are ways HIV escapes from the immune system
antigenic drift of gp120
inactivatino of key elements of immune response
cell to cell fusion
chemokine coreceptor antagonist
bind to corecetpro, prevent its interactino with gp120
fusion inhibtio
bind to gp41 and prevent conformatinoal changed needed for fusion of viral envelope with cellular plasma membrane
symptoms of neonate encephalitis
seizure, lethary, irrbiltility
What on HSV is targeted for antivirals
HSV polymerase
How do you diagnose HSV
tzanck smear
PCR
immunocytochemistry
How do you treat oral lesions (herpes)
you dont
How do you treat primary gential herpes
oral antiviral
how do you treat recurrent genital herpes
long term oral antival
how do you treat neonateal herpes
IV antibiral
how do you terat ocular herpes
topical antiviral
How do acyclovir work
use viral tk to inhibit (treats herpes)
foscarnet
treats herpes
use when HSV is acyclovir resistant
E2
inhibits production of E6/E
HPV E7
inhibits Rb
HPV E6
inhibits p53
how do you treat asympotmatic bacteriuria (if it needed to be treated
amoxicillin, cephalexin or nitrfurantoin
How do you terat gram negative pyelonephiritis
fluoroquiolones
How do you treat gram positive pyelonephritis
amoxicillin
how dyou treat treat uncomplicated cysitis
trimethoprim/sulfamethoazole
peritonitis
ab swelling/tenderness after trauma or sx
risk factors for enterococcus
prolonged hospitalization
treatment with broad spectrum abx
what are host defenses that prevent UTIs
low pH
high urea
flushing mechanisms of urine
