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micro exam 4 last minute Flashcards

1
Q

Kiolocytes are associated with what?

A

HPV

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2
Q

How do you treat syphilis if it is resistant to penicillin?

A

doxycycline

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3
Q

What are the chlamydia serovars?

A

trachoma

LGV

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4
Q

Syphilius ulcer

A

firm
painless
sharply demarcated

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5
Q

Herpes ulcer

A

bleeds
tender
multiple lesions

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6
Q

Chancriod ulcer

A

pustule
purulent, bleed easy
soft
tender

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7
Q

LGV ulcer

A

usually one

evelated, round or oval

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8
Q

Donovanosis ulcer

A

elevated

red and velverty, bleeds easily

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9
Q

What is associated with reiter syndrome

A

chlymidia

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10
Q

reiter syndrome triad

A

urethritis, conjunctivitis, polyartheritis

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11
Q

symptoms of LGV besides the papule

A

inguinal lymphadenopathy

buboes

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12
Q

How do you treat chlyamdia

A

doxycycline or macrolides

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13
Q

Which gonorrhea virulence factors undergo antigenic variation

A

opa
por
pilin
LOS

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14
Q

disseminated infection going into the joints is associated with

A

n. gonorrhoeae

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15
Q

How do you treat gonorrhea

A

ceftriaxone plus doxycycline or z pak

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16
Q

What do nontreponemal tests look for

A

cardiolipin

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17
Q

What do treponemal tests look for

A

t. pallidum

FTA-ABS antibody

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18
Q

What should you test your patient with urethritis for

A

gonorrhea and chlamydia

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19
Q

How do you treat M/. genitalium

A

azithromycin

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20
Q

How do you terat m. hominis

A

doxycyline

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21
Q

When is ureaplasma not typically found

A

before puberty

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22
Q

How do you treat ureaplasma

A

doxycylline

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23
Q

how do you treat reccurent non-gonococcal urethritis in men

A

azithromycin or quinolones

24
Q

How do you diagnose ducrey

A

slow growth on chocolate agar

chocolate agar with vanocmycin

25
Q

How do you treat ducrei

A

macrolide

26
Q

Hysterectomy with removal of cervix is associated with whiat

A

increase fragilis

increase e coli and enteroccus

27
Q

What is amsel critieria is used for

A

BV

28
Q

What are major criteria for tooxic shock

A

hyptension
synope
sunburn that peels

29
Q

What are the important proteins in HIV

A 
gp120
gp41
pol
p17
p24
30
Q

What does gp120 bind to

A

CD4

31
Q

function of gp41

A

mediates fusion between the viral envelop and plasma membrane

32
Q

pol gene

A

virally encoded enzyme

33
Q

acute HIV symptoms are similiar to what disease

A

mono

34
Q

What are ways HIV escapes from the immune system

A

antigenic drift of gp120
inactivatino of key elements of immune response
cell to cell fusion

35
Q

chemokine coreceptor antagonist

A

bind to corecetpro, prevent its interactino with gp120

36
Q

fusion inhibtio

A

bind to gp41 and prevent conformatinoal changed needed for fusion of viral envelope with cellular plasma membrane

37
Q

symptoms of neonate encephalitis

A

seizure, lethary, irrbiltility

38
Q

What on HSV is targeted for antivirals

A

HSV polymerase

39
Q

How do you diagnose HSV

A

tzanck smear
PCR
immunocytochemistry

40
Q

How do you treat oral lesions (herpes)

A

you dont

41
Q

How do you treat primary gential herpes

A

oral antiviral

42
Q

how do you treat recurrent genital herpes

A

long term oral antival

43
Q

how do you treat neonateal herpes

A

IV antibiral

44
Q

how do you terat ocular herpes

A

topical antiviral

45
Q

How do acyclovir work

A

use viral tk to inhibit (treats herpes)

46
Q

foscarnet

A

treats herpes

use when HSV is acyclovir resistant

47
Q

E2

A

inhibits production of E6/E

48
Q

HPV E7

A

inhibits Rb

49
Q

HPV E6

A

inhibits p53

50
Q

how do you treat asympotmatic bacteriuria (if it needed to be treated

A

amoxicillin, cephalexin or nitrfurantoin

51
Q

How do you terat gram negative pyelonephiritis

A

fluoroquiolones

52
Q

How do you treat gram positive pyelonephritis

A

amoxicillin

53
Q

how dyou treat treat uncomplicated cysitis

A

trimethoprim/sulfamethoazole

54
Q

peritonitis

A

ab swelling/tenderness after trauma or sx

55
Q

risk factors for enterococcus

A

prolonged hospitalization

treatment with broad spectrum abx

56
Q

what are host defenses that prevent UTIs

A

low pH
high urea
flushing mechanisms of urine

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