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MedBoardsPrep > Micro-Para-Virology > Flashcards

Micro-Para-Virology Flashcards

0
Q

Factor causing Necrosis in C. perfringens

A

£ Factor

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1
Q

Factor causing ‘whooping’ cough in Pertussis (Tuspirina)

A

Pretracheal cytotoxin

-damages ciliated cells

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2
Q

Current bird flu

A

H7N9

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3
Q

Factor for Hemoglobin breakdown in P.aeruginosa

A

Verdoglobin

  • pyocyanin - pigment damages colia & mucosal cells
  • exotoxin A - tsx necrosis; inactivates EF-2; TYPE III SECRETION SYSTEM - facilitates exotoxin transfer
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4
Q 
Pontiac fever
Shanghai fever
Staccato cough 
Bird Fancier's dsx
Valley fever
Damson Disease
Expatriate Syndrome
Tropical Pulmonary Eosinophilia
River blindness
A

Pontiac fever - Legionella (Silver stain)
Shanghai fever - Pseudomonas (Cetrimide agar)
Staccato cough - Chlamydia D-K (neonatal)
Bird Fancier’s dsx - C psittaci
Valley fever - Coccidioses
Damson Disease - SSPE
Expatriate Syndrome, Tropical Pulmonary Eosinophilia (Nocturnal wheezing) - Filariasis
River blindness - Drancunculus

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5
Q 
Thalamic infarcts
Katayama fever
Jacksonian Sz
Klatzkin's Tumor
PUD-like
Halzoun
Loeffler's Syndrome
A 
Thalamic infarcts - Jap B
Katayama fever, Jacksonian Sz - Schistosoma
Klatzkin's Tumor - C sinensis
PUD-like - Heterophyes, Metagonimus
Halzoun - F hepatica
Loeffler's Syndrome - Ascaris
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7
Q

Drugs for:
Tuberculoid Leprosy
Lepromatous Leprosy
Erythema nodosum Leprosum

A

Tuberculoid Leprosy
- Dapsone + Rifampicin
Lepromatous Leprosy
- Dapsone + Rifampicin + Clofazimine

*grows in foot pad of Armadillo
Erythema nodosum Leprosum
- Thalidomide

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8
Q

Gram positive funal-like

aerial hyphae

A

Nocardia asteroides
Mx: SMX-TMP (‘SNAP’)

*SMX Nocardia ; Actinomyces Pen

  • CM: mycetoma & abscesses (lung & brain “orange colonies”
  • Fite Faraco Stain
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9
Q 
Fite faraco Stain
Eaton medium
Regan Lowe Agar
MAnnitol Salt Agar
BSK Medium
Frei Test
Cycloxidine Culture
Circumoral Precipitin test
Loeffler's medium
Harada-Mori
A 
Fite faraco Stain - Nocardia
Eaton medium -Mycoplasma
Regan Lowe Agar - Bordetella
Mannitol Salt Agar - Staph
BSK Medium - Borrelia burg
Cycloxidine Culture - Chlamydia
Frei test - Chlamydia (LGV)
Circumoral Precipitin test - Schistosoma
Loeffler's medium - C diphtheriae
Harada-Mori - Strongyloides
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10
Q

Cold Agglutinin Syndrome

A

Mycoplasma pneumoniae

  • cold agglutinins - against RBC
  • cold temp: clots ; room temp: unclots

*toll like receptors 2 protein (P1 adhesin)

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11
Q

MC Infectious cause of SJS

A

Mycoplasma pneumoniae

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12
Q

Lacks Kreb’s cycle hence cannot be cultured in vitro

A

Treponema pallidum

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13
Q 
Ixodes ticks
Dermacentor
Peduculus humanus
Civet cat
Horseshoe bat
Culex mosquito
Mansonia
Blackfly
Deer fly
Mango fly
A 
Ixodes ticks - Borrelia burgdorferi; Babessia
Dermacentor - Franciscella; Erlichia
Peduculus humanus - Borrelia recurrentis
Civet cat - Corona (IH)
Horseshoe bat - Corona (reservoir)
Culex mosq - Jap B, Wuchureria
Mansonia - Brugia
Blackfly (female, Simulum) - Onchocerca
Deer fly, Mango fly (Chrysops) - Loa
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14
Q 
Reduviid bug (Triatoma)
Tse tse fly (Glossina)
Bivalve mollusks
Sandfly (Phlebotomus)
Oncolmelania hupensis quadrasi
Antemelania asperata
Sundathelphusa phil
A

Reduviid bug (Triatoma) - Tcruzi
Tse tse fly (Glossina) - T brucei
Bivalve mollusks - Dinoflagellates
Sandfly (Phlebotomus) - Leishmania
Oncolmelania hupensis quadrasi - Schistosoma (IH)
Antemelania asperata, Sundathelphusa phil - Paragonimus (IH)

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15
Q

Cutaneous Larva Migrans
Larvae Currens
Visceral Larva Migrans
Ocular larva Migrans

A

‘serpginous tracks’
CLM -Hookworms
Larvae Currens -Strongyloides

Visceral Larva Migrans, Ocular larva Migrans - Toxocara canis

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17
Q

Erythema chronicum migrans

A

Lyme Dsx
- Borrelia burgdorferi

2- AV block; Bell’s palsy
3- onion skin lesion; acrodermatitis chronica atrophicans

19
Q 
Owl's eyes
Koplik's spot
Nagayama spot
Negri bodies
Habestadter Prwazeki
Flower-like nucleus
Thread-like virus 
Threadworm
A 
Owl's eyes - CMV (Herpes)
Koplik's spot - Measles
Nagayama spot - Roseola 
Negri bodies - Rhabdo
Habestadter Prwazeki - Chlamydia trachomatis A-C
Flower-like nucleus - HTLV (Retro)
Thread-like virus - Ebola (Filo)
Threadworm - Strongyloides (Nema)
20
Q

Elementary body

Reticulate body

A 
Chlamydia
Elementary body 
- infectious
- inactive
- extracellular 
- enters body by endocytosis

Reticulate body

  • active
  • intracellular
21
Q

Inclusions in Chlamydia trachomatis type A-C

A

Haberstadter Prowazek

22
Q 
Henderson Peterson bodies
Warthin Finkeldy bodies
Guanerdin bodies
Ernst babes bodies
Meyer's Kouvenaar's bodies
A

Henderson Peterson bodies - Molluscum (Pox)
Warthin Finkeldy bodies - Measles (Paramyxo)
Guanerdin bodies - Vario/Smallpox (Pox)
Ernst babes bodies - Corynebac
Meyer’s Kouvenaar’s bodies - Filariasis

24
Q 
p24
gp120
gp41
tat
rev
vif
nef
vpu
A

p24 (gag)

  • nucleopcapsid
  • group specific (SEROLOGIC MARKER)

gp120 (env)

  • attachment
  • V3 LOOP - most immugenoc region
  • changes rapidly

gp41 (env)
- fusion

tat 
-activates transcription
rev
-transpot mRNA to cytoplasm
vif
-increases hypermutation
nef
-decreases CD4 & Class I MHC
vpu
-increases virion release
25
Q 
Maltese cross
Honeycomb vesicles
Barrel shaped proglotids
Barrel shaped eggs
Forked tail
A

Maltese cross - Babesia
Honeycomb vesicles - Echinococcus multilocularis
Barrel shaped proglotids - Dipylidium caninum
Barrel shapes eggs - Trichuris
Forked tail - Schistosoma

26
Q 
Anchovy-sauce aspirate
Durck granulomas
Ring- enhancing lesions
Ring - shadow opacity
Intracranial calcifications
Mott cells
Mariner's wheel
Nocturnal periodicity
Nocturnal wheezing
A

Anchovy-sauce aspirate - E. hystol
Durck granulomas - Malaria
Ring- enhancing lesions - T gondii (enceph)
Ring - shadow opacity CXR - Paragonimus
Intracranial calcifications - T gondii (congenital)
Mott cells - T brucei
Mariner’s wheel - Paracoccidioses
Nocturnal periodicity, Nocturnal wheezing - Filariasis
Calabar swelling - Loa Loa

28
Q

Heterophile Monospot Test

A

(+) EBV

(-) CMV T.gondii

29
Q

Most frequently infected tissue in Chaga’s Dsz

A

Cardiac muscle

30
Q

Ulcers:
Flask shaped
Wide based

A

Ulcers:
Flask shaped - E hystolytica
Wide based - Balantidium coli

31
Q

MCC of Parasitic Meningitis

A

Angiostrongylus cantonensis

32
Q

Parasite causing
Appendicitis

Paradoxical Asthma

A

AP

  • Entorobius
  • Yersinis enterolytica (Mesenteric Adenitis)

BA
-Strongyloides

33
Q 
Romana's sign
Kerandel's sign
Winterbottom sign
Dessert Bumps
Ground itch
Swimmer's itch
A

Romana’s sign - unilat periorbital edema (Chaga’s)
Kerandel’s sign - hyperesthesia (Sleeping sickness)
Winterbottom sign - post CLAD (Sleeping sickness)
Erythema Nodosum ‘Dessert Bumps’ - Coccidioses
Ground itch - Hookworms, Strongyloides
Swimmer’s itch - Schistosoma

34
Q

Saxitoxin
Okadaic toxin
Brevetoxin
Domoic toxin

A

Saxitoxin - Paralytic (15min)
Okadaic toxin - Diarrheic (30min
Brevetoxin - Neurologic (15min)
Domoic toxin - Amnesic (30min)

35
Q

Only:
Virus with Fiber
Ciliated protozoan causing dsx

A

Only:
Virus with Fiber- Adenovirus
Ciliated protozoan causing dsx - Balatidium coli

36
Q 
DOC:
Leishmania
Cysticercosis???
Chaga's
Cryptococcosis
Toxoplasmosis
A 
DOC:
Leishmania - Stibogulconate
Cysticercosis??? - TMP-SMX
Chaga's- Nifurtimox
Cryptococcosis - Nitrazoxamide
Toxoplasmosis - Sulfadiazine-Pyrimethamine

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