Tissue and Inflammation

Question 0

Mediators of Brochial asthma

Answer 0

SRSA (Slow Respons Substance Anaphylaxis)

Leukotrienes C4 D4 E4

Question 1

Hallmark of Acute Inflammation

Answer 1

vascular permeability

Question 2

Permanent cells

Answer 2

Neurons
Skeletal muscles
Cardiac muscles

Question 3

Stable cells

quiescent cells @G0 phase. Low replication but can undergo rapid diision on stiumli

Answer 3

Liver
Pancreas
Kidneys

Question 4

Collagen disorder in Knobloch syndrome and Epidermolysis bullosa

Answer 4

Type XVIII - Knobloch

Epidermolysis bullosa
Type VII (dermoepidermal junction)
Type XVII (Epidermal cells)

Question 5

% of blood loss in Hemorrhagic Shock

Answer 5

40%

Question 6

Receptors for platelet adhesion and aggregration

Answer 6

Adhesion - gpIb
Aggregation - gpIIb-IIIa

‘only 1 to adhere but MANY to clump all the platelets’

Question 7

Virchow’s Triad

Answer 7

Endothelial injury
Hypercoagulable
Stasis (abnormal blood flow)

Question 8

Pathophysio of APAS

Answer 8

Ab mediated inhibition of tPA

anticardiolipin and anticoagulant

Question 9

Diffenrence between Ante-mortem and Post-mortem thrombosis

Answer 9

Lamination ‘Lines of Zahn’

In Ante mortem thrombosis

Question 10

Where do you find sterile vegetations of Non bacterial thrombotic endocarditis

Answer 10

Marantic Endocarditis

-assoc with malignancy & Strep bovis (Type 1 or Strep gallolyticus)

Question 11

Malignancies caused by Asbestos and Arsenic

Answer 11

Asbestos - Malignant Mesithelioma if the Lung

Arsenic - Hepatic Angiosarcoma