micro - antimicrobials part 2

Question 1

antibiotics to avoid in preggers

Answer 1

SAFe Children Take Really Good Care

sulfonamides, aminoglycosides, fluoroquinolones, clarithromycin, tetracyclines, ribavirin, griseofulvin, chloramphenicol

Question 2

AP: sulfonamides

Answer 2

kernicterus

Question 3

AP: aminoglycosides

Answer 3

ototoxicity

Question 4

AP: fluroquinolones

Answer 4

cartilage damage

Question 5

AP: clarithromycin

Answer 5

embryotoxic

Question 6

AP: tetracyclines

Answer 6

discolored teeth/ inhibit bone growth

Question 7

AP: ribavirin

Answer 7

teratogenic

Question 8

AP: griseofulvin

Answer 8

teratogenic

Question 9

AP: chloramphenicol

Answer 9

gray baby syndrome

Question 10

interferons MOA

Answer 10

virus infected cell synthesizes these glycoproteins –> prevent replication of DNA and RNA viruses

Question 11

interferons alpha clinical uses

Answer 11

chronic hep B and C, kaposis sarcoma

Question 12

interferons beta clinical uses

Answer 12

MS

Question 13

interferons gamma clinical uses

Answer 13

NADPH oxidase deficiency

Question 14

interferon toxicity

Answer 14

neutropenia and myopathy