MG/LEMS Flashcards
1
Q
3ish Associated Disorders w/ MG
A
Thymoma/hyperplastic thymus
Hyper/hypothyroidism
Other AI disorders
2
Q
Tensilon Test
A
Edrophonium test for MG, use short acting AChE inhibitor and see if it works
3
Q
3+ Treatments for MG
A
Anti-AChEs, then steroids, then immunosuppressive drugs, then more severe
4
Q
LEMS as Warning SIgn
A
Often Precedes cancer
5
Q
2 Autonomic Signs of LEMS
A
Dry mouth, impotence in men
6
Q
Big Pathophys Difference b/w MG and LEMS
A
MG defect is postsynaptic, LEMS is presynaptic at active zones
7
Q
Treatment for LEMS
A
3,4-Diaminopyridine blocks outward K+ current, prolonging duration of presynaptic AP
