Metabolism / BIiochemical Pathways Flashcards

1
Q

Sum total of all chemical reactions in order to maintain life

A

Metabolism

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2
Q

▪️Breaking Down (-lysis)
▪️Complex -> Simple
▪️Energy Producing

A

Catabolism

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3
Q

▪️Building up (-genesis)
▪️Simple -> Complex
▪️ATP/ Energy Requiring

A

Anabolism

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4
Q

Combination of catabolic and anabolic reactions

Ex. Krebs Cycle

A

Amphibolic

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5
Q

FED STATE (2)

A

▪️Glycolysis
▪️Glycogenesis

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6
Q

FASTED STATE (2)

A

▪️Glycogenolysis
▪️Gluconeogenesis

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7
Q

What Pathway is Glucose to Pyruvate?

A

Glycolysis

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8
Q

What Pathway is Glucose to Glycogen?

A

Glycogenesis

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9
Q

What Pathway is Glycogen to Glucose?

A

Glycogenolysis

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10
Q

What Pathway is Non-Carb Precursos to Glucose

A

Gluconeogenesis

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11
Q

METABOLISM PROCESSES OCCURS AT: Mitochondria (4)

A

▪️TCA (Krebs Cycle)
▪️ETC
▪️B-Oxidation
▪️Ketogenesis

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12
Q

METABOLISM PROCESSES OCCURS AT: Cytosol

A

▪️Glycolysis
▪️Glycogenesis
▪️Glycogenolysis
▪️PPP
▪️FA Synthesis
▪️Cholesterol Syntheisis

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13
Q

METABOLISM PROCESSES OCCURS AT: Both in Mitochondria & Cytosol

A

▪️Gluconeogenesis (Mitochondria-Steps 1 & 2 | Cytosol-Steps 3-11)

▪️Urea Cycle (Mitochondria-Step 1 | Cytosol Steps 2 to 4)

▪️Heme Synthesis

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14
Q

Irreversible Step of Glycolysis (3)

A

Step 1,3, 10

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15
Q

Rate limiting step of Glycolysis

A

Step 3- Phosphofructokinase

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16
Q

Irreversible step of Gluconeogenesis

A

Step 1,2,8,10

17
Q

Rate limiting step of Gluconeogenesis

A

Step 8- fructose 1,6 - biphosphatase

18
Q

Energy Investment/Spending in Glycolysis

19
Q

Energy Pay-off Phase/Generation/Produce

A

Steps 6-10

20
Q

Fates of Pyruvate 2 Rxns

A
  1. Aerobic Reaction (1)
  2. Anaerobic Reaction (2)
21
Q

Aerobic Rxn
Process: Oxidative Decarboxylation
Enzyme:

A

Pyruvate Dehydrogenase

22
Q

Aerobic Rxn
Process:
Enzyme: Pyruvate Dehydrogenase

A

Oxidative Decarboxylation

23
Q

Anaerobic Rxn
Process: Dehydrogenation
Enzyme:

A

Lactate Dehydrogenase

24
Q

Anaerobic Rxn
Process:
Enzyme: Lactate Dehydrogenase

A

Dehydrogenation

25
Anaerobic Rxn Process: Fermentation Enzyme:
Pyruvate Decarboxylase
26
Anaerobic Rxn Process: Enzyme: Pyruvate Decarboxylase
Fermentation
27
Product of Aerobic Rxn
2 Acetyl CoA - producing 2 NADH that equals to 6 ATP
28
Product of Lactate Dehydrogenase
Lactic Acid
29
Product of Pyruvate Decarboxylase
Acetaldehyde (that will turn to ethanol through alcohol dehydrogenase)
30
Rate limiting step in Krebs Cycle
Step 3: Isocitrate Dehydrogenase
31
How many; (in Krebs Cycle) ▪️NADH ▪️FADH2 ▪️GTP ▪️CO2
▪️3 NADH (Steps 3,4,8) ▪️1 FADH2 (Step 6) ▪️1 GTP (Step 5) ▪️ 2 CO2
32
End Products of Krebs Cycle
▪️3 NADH (Steps 3,4,8) ▪️1 FADH2 (Step 6) ▪️1 GTP (Step 5) ▪️ 2 CO2
33
Rate limiting step of glycogenesis
Glycogen synthase
34
Rate limiting step of Glycogenolysis
Glycogen phosphorylase
35
Rate limiting step of Pentose Phosphate Pathway
Glucose-6-phosphate dehydrogenase
36
2 Phase of PPP
1. Oxidative Phase 2. Non-Oxidative Phase
37
Final product of oxidative phase of PPP
Ribulose-5-Phosphate