Metabolism / BIiochemical Pathways

Question 1

Sum total of all chemical reactions in order to maintain life

Answer 1

Metabolism

Question 2

▪️Breaking Down (-lysis)
▪️Complex -> Simple
▪️Energy Producing

Answer 2

Catabolism

Question 3

▪️Building up (-genesis)
▪️Simple -> Complex
▪️ATP/ Energy Requiring

Answer 3

Anabolism

Question 4

Combination of catabolic and anabolic reactions

Ex. Krebs Cycle

Answer 4

Amphibolic

Question 5

FED STATE (2)

Answer 5

▪️Glycolysis
▪️Glycogenesis

Question 6

FASTED STATE (2)

Answer 6

▪️Glycogenolysis
▪️Gluconeogenesis

Question 7

What Pathway is Glucose to Pyruvate?

Answer 7

Glycolysis

Question 8

What Pathway is Glucose to Glycogen?

Answer 8

Glycogenesis

Question 9

What Pathway is Glycogen to Glucose?

Answer 9

Glycogenolysis

Question 10

What Pathway is Non-Carb Precursos to Glucose

Answer 10

Gluconeogenesis

Question 11

METABOLISM PROCESSES OCCURS AT: Mitochondria (4)

Answer 11

▪️TCA (Krebs Cycle)
▪️ETC
▪️B-Oxidation
▪️Ketogenesis

Question 12

METABOLISM PROCESSES OCCURS AT: Cytosol

Answer 12

▪️Glycolysis
▪️Glycogenesis
▪️Glycogenolysis
▪️PPP
▪️FA Synthesis
▪️Cholesterol Syntheisis

Question 13

METABOLISM PROCESSES OCCURS AT: Both in Mitochondria & Cytosol

Answer 13

▪️Gluconeogenesis (Mitochondria-Steps 1 & 2 | Cytosol-Steps 3-11)

▪️Urea Cycle (Mitochondria-Step 1 | Cytosol Steps 2 to 4)

▪️Heme Synthesis

Question 14

Irreversible Step of Glycolysis (3)

Answer 14

Step 1,3, 10

Question 15

Rate limiting step of Glycolysis

Answer 15

Step 3- Phosphofructokinase

Question 16

Irreversible step of Gluconeogenesis

Answer 16

Step 1,2,8,10

Question 17

Rate limiting step of Gluconeogenesis

Answer 17

Step 8- fructose 1,6 - biphosphatase

Question 18

Energy Investment/Spending in Glycolysis

Answer 18

Steps 1-5

Question 19

Energy Pay-off Phase/Generation/Produce

Answer 19

Steps 6-10

Question 20

Fates of Pyruvate 2 Rxns

Answer 20

1. Aerobic Reaction (1)
2. Anaerobic Reaction (2)

Question 21

Aerobic Rxn
Process: Oxidative Decarboxylation
Enzyme:

Answer 21

Pyruvate Dehydrogenase

Question 22

Aerobic Rxn
Process:
Enzyme: Pyruvate Dehydrogenase

Answer 22

Oxidative Decarboxylation

Question 23

Anaerobic Rxn
Process: Dehydrogenation
Enzyme:

Answer 23

Lactate Dehydrogenase

Question 24

Anaerobic Rxn
Process:
Enzyme: Lactate Dehydrogenase

Answer 24

Dehydrogenation

Question 25

Anaerobic Rxn
Process: Fermentation
Enzyme:

Answer 25

Pyruvate Decarboxylase

Question 26

Anaerobic Rxn
Process:
Enzyme: Pyruvate Decarboxylase

Answer 26

Fermentation

Question 27

Product of Aerobic Rxn

Answer 27

2 Acetyl CoA - producing 2 NADH that equals to 6 ATP

Question 28

Product of Lactate Dehydrogenase

Answer 28

Lactic Acid

Question 29

Product of Pyruvate Decarboxylase

Answer 29

Acetaldehyde (that will turn to ethanol through alcohol dehydrogenase)

Question 30

Rate limiting step in Krebs Cycle

Answer 30

Step 3: Isocitrate Dehydrogenase

Question 31

How many; (in Krebs Cycle)
▪️NADH
▪️FADH2
▪️GTP
▪️CO2

Answer 31

▪️3 NADH (Steps 3,4,8)
▪️1 FADH2 (Step 6)
▪️1 GTP (Step 5)
▪️ 2 CO2

Question 32

End Products of Krebs Cycle

Answer 32

▪️3 NADH (Steps 3,4,8)
▪️1 FADH2 (Step 6)
▪️1 GTP (Step 5)
▪️ 2 CO2

Question 33

Rate limiting step of glycogenesis

Answer 33

Glycogen synthase

Question 34

Rate limiting step of Glycogenolysis

Answer 34

Glycogen phosphorylase

Question 35

Rate limiting step of Pentose Phosphate Pathway

Answer 35

Glucose-6-phosphate dehydrogenase

Question 36

2 Phase of PPP

Answer 36

1. Oxidative Phase
2. Non-Oxidative Phase

Question 37

Final product of oxidative phase of PPP

Answer 37

Ribulose-5-Phosphate