metabolic pathways 2.1 Flashcards

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1
Q

cell metabolism

A

the sum of all biochemical reactions which take place in living cells

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2
Q

break down of larger molecules into smaller molecules which results in energy being released

A

catabolic pathways

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3
Q

small simple molecules joining together to form a larger complex molecule which requires energy

A

anabolic pathways

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4
Q

ATPs role is to transfer energy between ……. reactions and ……….. reactions in cells

A

catabolic
anabolic

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5
Q

why do alternative routes for metabolic pathways exist

A

if a specific enzyme or substrate isnt available in the pathway

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6
Q

what are membranes composed of

A

phospholipids and proteins

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7
Q

forms channels or….. across the membrane
allows diffusion of larger molecules

A

protein pores

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8
Q

-molecules move from higher to lower concentration down a concentration gradient
-passive process

A

diffusion

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9
Q

transports molecules by active transport
from lower to higher concentration against against the concentration gradient
requires energy provided by ATP

A

protein pumps

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10
Q

catalyse steps in metabolic pathways
e.g. ATP synthase

A

proteins as enzymes in cell membranes

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11
Q

how do enzymes speed up biochemical reactions

A

lowering the activation energy

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12
Q

why are enzymes necessary

A

because biochemical reactions must take place at a fast enough rate for survival

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13
Q

what happens to the active site when the substrate binds to the enzyme

A

the enzyme changes shape slightly to better fit the substrate this is induced fit.

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14
Q

the substrate has a ………… affinity for the active site

A

high

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15
Q

the subsequent products have a ……. infinity allowing them to leave the active site

A

low

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16
Q

why would a reversible reaction be useful

A

to restore the balance of a metabolites pathway, can be used to store products

17
Q

-similar shape and and charge to enzymes substrate
-binds at the active site
-increasing substrate concentration results in an increase reaction rate
-leaves the enzyme still usable

A

competitive inhibitors

18
Q

-binds to the allosteric site
-causes a conformation change so the substrate can no longer bind
-the maximum rate of reaction will be lower as there are less usable enzymes

A

non-competitive inhibitors

19
Q

-the end product of the enzyme binds to the first enzyme in the pathway
- slows the rate or the first reaction
- rate of reaction is controlled to prevent the build up of excess end product
saves energy and resources

A

feedback inhibition by an end product

end product inhibition