Memory and Cognition Flashcards

1
Q

Define Cognition

A

The integration of all sensory information to make sense of a situation

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2
Q

Name the three parts of the brain involved in learning and memory

A

Hippocampus, Cortex and Thalamus

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3
Q

What is the function of the hippocampus?

A

Formation of memories

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4
Q

What is the function of the cortex?

A

Storage of memories

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5
Q

What is the function of the thalamus?

A

Searches and accesses memories

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6
Q

What is the significance of the limbic system in relation to memory?

A

To give events emotional significance - which is essential for memory

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7
Q

What are the components of the limbic system?

A

Amygdala, cingulate gyrus, hippocampus and the hypothalamus

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8
Q

What is the function of the limbic system?

A

To control instinctive behaviour such as thirst, sex, hunger etc. and emotive behavious by seeking reward/puishment

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9
Q

What drives motivation?

A

Reward or punishment

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10
Q

What occurs in patients with bilateral hippocampal damage?

A

Immediate and long term memory in tact but are unable to form new memories

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11
Q

Define immediate or sensory memory

A

Memory which lasts a few seconds

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12
Q

Define short-term memory

A

Memory which lasts seconds-hours. Used for short term tasks and is associated with reverberating circuits

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13
Q

Define immediate long-term memory

A

Memory which lasts hours to weeks. Associated with chemical adaptation at the presynaptic terminal

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14
Q

Define long-term memory

A

Can be lifelong. Associated with structural changes in synaptic connections

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15
Q

Describe the concept behind reverberating circuits?

A

Each synapse in a reverb. circuit is excitatory and hence a brief excitatory stimulus at A will cause a long lasting neuronal activity in B

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16
Q

Describe anterograde amnesia

A

Inability to recall events which occur after the injury. Can be short lived or permenant

17
Q

Describe retrograde amnesia

A

Cannot remember events leading up to the injury although memories formed long time ago are usually unaffected

18
Q

if only the thalamus is damaged and the hippocampus is spared, what occurs?

A

Retrograde amnesia

19
Q

How is intermediate long term memory produced?

A

Chemical changes in presynaptic neurons by increasing Ca2+ entry into presynaptic terminals which increases neurotransmitter release

20
Q

Describe the mechanism behind long term memory

A

Structural changes at synapses occur via either an increase in NT release sites/ NT vesicles stored and released/ number of presynaptic terminals which occurs at same time as LTP

21
Q

Describe LTP

A

An increased amplitude of EPSP occurs in post synaptic cell. Results in well rehearsed pattern of neuronal firing unique to a particular memory

22
Q

Name the two types of long term memory

A

Explicit/Declarative memory and Reflexive/Implicit memory

23
Q

What is declarative memory?

A

Abstract memory for events and for words, rules and language. Relies on hippocampus

24
Q

What is reflexive memory?

A

Acquired through repetition. Includes motor memory for acquired skills. Based in cerebellum and is independent of hippocampus

25
Q

How is short term memory converted into long term memory?

A

Consolidation