Membrane Potential Flashcards
ICF and ECF charges
ICF has an excess of anions
ECF has an excess of cations
Ion channels provide selective ion permeability
Electrical gradient and concentration gradient relationship
Electrical gradient Opposes an ion concentration gradient across a cell membrane
All living cells have a resting membrane potential based on a separation of charge across the cell membrane
What maintains the gradient for the Na and K ions?
The sodium potassium pump
The sodium potassium pump
Pumps three sodium out of the cell for every two potassium into the cell per ATP molecule
Contributes towards the membrane potential
Neurons have a high number of sodium and potassium pumps to reestablish, potassium and sodium gradients necessary for action potentials
Sodium details
Intracellular is less than extra cellular
potential is +67
Potassium details
Extracellular is less than intracellular
potential is -95
Calcium details
Intracellular is less than extra cellular
potential is +123
Chlorine details
Intracellular is less than extra cellular
potential is -89
HCO3 bicarbonate
Intracellular is less than extra cellular
Potential is -19
Depolarization
Sodium is entering
Repolarization
Potassium is leaving
Absolute refractory. Period
Beginning of one action potential, when it is impossible to stimulate, and produce another action potential
Sodium channel gates are closed and inactive
Relative refractory Period
Comes right after that absolute refractory. Period
If there’s another impulse or stimulus given, it could trigger a response, but only if it is a stronger stimulus
This is because the sodium channels have recovered