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UE2 Biocell > Meiose > Flashcards

Meiose Flashcards

1
Q

quelle phase cx synaptonemal entierement constitue

A

pachyteme

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2
Q

🔥 qd se deatche chromosomes de env nucelaire

A

stade diacinese

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3
Q

🔥Les chromatides sont visibles dès le stade leptotène.

A

non car que debut de condensation

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4
Q

role de SGO

A

empeche inactivation de la cohesine du centromere

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5
Q

🔥fuseau occupe une position cell excentree lors des 2 divisions meoitiques de l’ovocyte

A

vrai

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6
Q

meiose = ‘succession de mitoses’

A

vrai

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7
Q

nb de chromatides et nd mold ADN en metaphase de mitose ?

A

92 chromatides et mol ADN

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8
Q

La paire de chromosomes n° 1 fournira 4 chromosomes, 2 pour chaque cellule fille

A

vrai mais faux selon medisup annales

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9
Q

diff 2N et 2C

A

2N : nombre de chromosones (n= nb de paires)

2C =qte AND

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10
Q

qte ADN avt replication

A

2C puis 4C apres replication

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11
Q

reperer diacienese

A

rupture env

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12
Q

diff visuelle metaphase 1 et 2

A

alignement des chiasmas (chromonsoes HOMO apparies) vs alignement des centromeres

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13
Q

reperer pachytene

A

cx syna et appa total

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14
Q

reperer zygotene

A

debut appariement

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15
Q

2n peut etre impair ?

A

non car nb de chromosne s tjs pair

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16
Q

a chaque division de meoise q ADN divise par 2

A

oui !!!

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17
Q

🔥metaphase 1 de meoise : association des homologues par les kinetochores

A

non

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18
Q

oeuf = gamete ?

A

oui

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19
Q

oeuf fertlise : qui

A

zygote

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20
Q

revoir images des diff stades

A

yo

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21
Q

qd segregation des homologues

A

meoise 1

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22
Q

🔥duplication de ADN : cohesine enserre le centromere

A

non ausi AXIALE

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23
Q

mitose bloquee pdt meoise eet vie et ersa

A

oui

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24
Q

phase S de meoise = m enzymes et meca que mitose m origines de repl

A

oiui

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25
Q

🔥ou se trouvent centrosomes interpphase vs propahse

A

cyto vs noyau

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26
Q

qd debut de recombi :

A

LETPTENE

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27
Q

🔥qd et what happens during reorganisaiton des chormo

A

telomeres s’agregent ss env nuc (Lepto)

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28
Q

🔥chromosomes X et Y ont des seq aux extremites qui sont proches et permettent appariement

A

oui

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29
Q

🔥distance entre chromosomes homologues Lepto

A

400nm

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30
Q

role Spo11

A

Lepto : cassure du doble brin adn

31
Q

🔥quelles enz de recombinaison (lep)

A

DMC1 RAD51

32
Q

recombinaison et app aux niveaux des regions complementaires

A

yes

33
Q

cassures du double brin : localisation aleatoire

A

non sites preferetiels

34
Q

DMC1 RAD51 (lep) invasion du simple ou double brin

A

simple

35
Q

q stade cassure de ADN

A

lep par spo11

36
Q

🔥cassure brin adn lepto : raccoursimenten 5’ ou 3’

A

5’

37
Q

mutant de spo111 : appareiement limite

A

yes et erruers de segragations

38
Q

🔥distance chrmo apparies en zy

A

100nm

39
Q

constituant principal du cx synap

A

filments transversux

40
Q

🔥struc filments transversux

A

N (centre ) et C(extremite) globulaire

partie centralemfaiscaeau en helices (batonnets)

41
Q

def recombi homologue **

A

interactin entre mol adn cassee et intctes qui favroisent la reparation

42
Q

P : fusion complete des chrmo

A

yes

43
Q

fin de P : decondenation des chromo

A

yes

44
Q

de qd a qd cx syna

A

Z-fin P

45
Q

P : cx synp desagres

A

yes

46
Q

🔥P : 3 etapes echanges de bras

A

allongement du brin ADN - capture et extension 2e extr - lig adn et formation jonciton double

47
Q

P : 3 etapes du retour a initail

A

elongatin ADN - disso des brins – retour vers son homologue et extension

48
Q

a q stade echanges de bras

A

pachytene

49
Q

echange de bras : formation d’une jonction double ou simple

A

double

50
Q

🔥a partir de qd voit on les chiasmas

A

diplo

51
Q

de qd a qd recombi

A

leptotene : cassure ADN - zy : decision de crossing over - di : ligature ou clivage/reparation deADN

52
Q

🔥cohesine partout

A

non pas au niveau des chiasma

53
Q

🔥pq pas de cohesine au niveau des chaismas

A

coheinse phosp par plk

54
Q

crossing over possibes partout

A

PAS au niveau de centrimeres

55
Q

🔥qd migration des centroomomes

A

diacines

56
Q

M1 : sys de controle de attachement des chromomses id a celui de a mitose

A

non

57
Q

🔥metaphase 1 : APC activee ?

A

oui donc separaseclivee

58
Q

metaphase 1 : separase clivee

A

oui

59
Q

q prot proetege cohesine en meta1

A

sgo1

60
Q

role coheinse

A

mainteneir les chromatides soeurs

61
Q

🔥diff duplique vs haploide

A

duplique = 2 chromatides - haploides : n chromoes

62
Q

M2 immedia pres M1

A

oui

63
Q

tjs cohesine en meta M2

A

non

64
Q

fin de M1 : reformation du noyau et decondesa des chromo systeme

A

non

65
Q

ct in evite nouvelle synthese ADN

A

inactivation des cdk/cyclines que partiellemt (encore un peu de aPC)

66
Q

🔥cellules filles de la M!e si j’ai un paire de chrom a la baee

A

2 cellules : a n chromsomes (halpoides) mais dupliques

67
Q

1 paire de chrom homologues et 2 chiasmas : cb de gametes dif

A

4

68
Q

cell filles de M2

A

n chroomsomes 1 chromtine

69
Q

mitose : aligment des chorom homologues sur la plaque meta

A

non !

70
Q

🔥mitose et meoise on obtient m nb de cell a la fin

A

non 2 cell file smitoses vs 4 gametes

71
Q

role de la mitose

A

formation d’organismes multicell a partir d’un zygote

72
Q

lepto : enz clivante de adn

A

yes –> reparation et echange

73
Q

pachytene : 4 chromosomes en photo on voit cb de centromeres

A

2 centromeres car chromomsone apparies = fusionnes

UE2 Biocell (15 decks)

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