Medicine (2)

Question 1

Drugs and duration for TB treatment

Answer 1

Question 2

SEs of TB drugs

Answer 2

Question 3

Name chemotherapy agents for lung ca

Answer 3

• gefitinib
• pemetrexed
• erlotinib

Chemotherapy for advanced

• docetaxel
• gemcitabine
• paclitaxel
• vinorelbine + platinum drug

Question 4

Name causes of bronchiectasis

Answer 4

Question 5

Management of pneumothorax

Answer 5

Question 6

Causes of jaundice (3 categories) + what hepatic picture is seen on the bloods

Answer 6

Question 7

Treatment of Hep B

Answer 7

• Symptomatic treatment should be given for nausea/pain or itch
• Local Health Protection Unit need to be notified
• PEGylated interferon-alpha as first-line treatment

Question 8

Treatment of Hep C

Answer 8

• usually a combination of protease inhibitors (e.g. daclatasvir) with or without ribavirin are used
• liver transplantation is the treatment of choice for patients with end-stage liver disease

Question 9

Management of acute liver failure

Answer 9

Question 10

Management of chronic liver failure

Answer 10

Question 11

Shortly about Willson’s disease

• pathogenesis
• Ix and Dx
• management

Answer 11

Question 12

Shortly about Hereditary Haemochromatosis

• pathogenesis
• Ix and Dx
• management

Answer 12

Question 13

Shortly about Primary Billary Cirrhosis (PBC)

• pathogenesis
• Ix and Dx
• management

Answer 13

Question 14

Shortly about Primary Sclerosing Cholangitis (PSC)

• pathogenesis
• Ix and Dx
• management

Answer 14

Question 15

PBC vs PSC

Answer 15

Question 16

Investigations and initial management in upper GI bleed

Answer 16

Question 17

(2) scores and their aims for the patient with upper GI bleed

Answer 17

Question 18

Management of variceal vs non - variceal upper GI bleed

Answer 18

Question 19

Management of oesophageal varices

Answer 19

Question 21

Possible differentials for change in bowel habits

Answer 21

Question 22

Differentials for Erythema Nodosum

Answer 22

Question 23

Differentials for pyoderma gangrenosum

Answer 23

Question 24

UC vs Crohn’s (simply)

Answer 24

Question 25

What are the extra-intestinal features of IBD?

Answer 25

Question 26

Multi-systemic causes of **clubbing**

Answer 26

Question 27

Acute treatment of Crohn's

Answer 27

Question 28

Long term Crohn's treatment

Answer 28

Question 29

***Azathioprine*** MoA Drug interaction with?

Answer 29

***Azathioprine*** ## Footnote **MoA:** inhibition of purine synthesis → inhibits cell proliferation (particularly lymphocytes) **Interaction with:** Allopurinol

Question 30

Azathioprine - what bloods to do before starting it?

Answer 30

***Azathioprine*** ## Footnote **Bloods before:** **TMPT** *(Thiopurine methyltransferase)*→ to look for increased risk of ***azathioprine*** toxicity

Question 31

SEs of Azathioprine

Answer 31

* Bone marrow depression * Nausea/vomiting * Pancreatitis * Increased risk of skin cancer (non-melanoma)