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Lancaster FINALS _slide > Medicine (2) > Flashcards

Medicine (2) Flashcards

1
Q

Drugs and duration for TB treatment

A
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2
Q

SEs of TB drugs

A
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3
Q

Name chemotherapy agents for lung ca

A
  • gefitinib
  • pemetrexed
  • erlotinib

Chemotherapy for advanced

  • docetaxel
  • gemcitabine
  • paclitaxel
  • vinorelbine + platinum drug
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4
Q

Name causes of bronchiectasis

A
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5
Q

Management of pneumothorax

A
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6
Q

Causes of jaundice (3 categories) + what hepatic picture is seen on the bloods

A
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7
Q

Treatment of Hep B

A
  • Symptomatic treatment should be given for nausea/pain or itch
  • Local Health Protection Unit need to be notified
  • PEGylated interferon-alpha as first-line treatment
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8
Q

Treatment of Hep C

A
  • usually a combination of protease inhibitors (e.g. daclatasvir) with or without ribavirin are used
  • liver transplantation is the treatment of choice for patients with end-stage liver disease
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9
Q

Management of acute liver failure

A
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10
Q

Management of chronic liver failure

A
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11
Q

Shortly about Willson’s disease

  • pathogenesis
  • Ix and Dx
  • management
A
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12
Q

Shortly about Hereditary Haemochromatosis

  • pathogenesis
  • Ix and Dx
  • management
A
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13
Q

Shortly about Primary Billary Cirrhosis (PBC)

  • pathogenesis
  • Ix and Dx
  • management
A
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14
Q

Shortly about Primary Sclerosing Cholangitis (PSC)

  • pathogenesis
  • Ix and Dx
  • management
A
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15
Q

PBC vs PSC

A
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16
Q

Investigations and initial management in upper GI bleed

17
Q

(2) scores and their aims for the patient with upper GI bleed

18
Q

Management of variceal vs non - variceal upper GI bleed

19
Q

Management of oesophageal varices

21
Q

Possible differentials for change in bowel habits

22
Q

Differentials for Erythema Nodosum

23
Q

Differentials for pyoderma gangrenosum

24
Q

UC vs Crohn’s (simply)

25
Q

What are the extra-intestinal features of IBD?

26
Q

Multi-systemic causes of clubbing

27
Q

Acute treatment of Crohn’s

28
Q

Long term Crohn’s treatment

29
Q

Azathioprine

MoA

Drug interaction with?

A

Azathioprine

MoA: inhibition of purine synthesis → inhibits cell proliferation (particularly lymphocytes)

Interaction with: Allopurinol

30
Q

Azathioprine

  • what bloods to do before starting it?
A

Azathioprine

Bloods before: TMPT (Thiopurine methyltransferase)→ to look for increased risk of azathioprine toxicity

31
Q

SEs of Azathioprine

A
  • Bone marrow depression
  • Nausea/vomiting
  • Pancreatitis
  • Increased risk of skin cancer (non-melanoma)

Lancaster FINALS _slide (31 decks)

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