Medicine (2) Flashcards
Drugs and duration for TB treatment
SEs of TB drugs
Name chemotherapy agents for lung ca
- gefitinib
- pemetrexed
- erlotinib
Chemotherapy for advanced
- docetaxel
- gemcitabine
- paclitaxel
- vinorelbine + platinum drug
Name causes of bronchiectasis
Management of pneumothorax
Causes of jaundice (3 categories) + what hepatic picture is seen on the bloods
Treatment of Hep B
- Symptomatic treatment should be given for nausea/pain or itch
- Local Health Protection Unit need to be notified
- PEGylated interferon-alpha as first-line treatment
Treatment of Hep C
- usually a combination of protease inhibitors (e.g. daclatasvir) with or without ribavirin are used
- liver transplantation is the treatment of choice for patients with end-stage liver disease
Management of acute liver failure
Management of chronic liver failure
Shortly about Willson’s disease
- pathogenesis
- Ix and Dx
- management
Shortly about Hereditary Haemochromatosis
- pathogenesis
- Ix and Dx
- management
Shortly about Primary Billary Cirrhosis (PBC)
- pathogenesis
- Ix and Dx
- management
Shortly about Primary Sclerosing Cholangitis (PSC)
- pathogenesis
- Ix and Dx
- management
PBC vs PSC
Investigations and initial management in upper GI bleed
(2) scores and their aims for the patient with upper GI bleed
Management of variceal vs non - variceal upper GI bleed
Management of oesophageal varices
Possible differentials for change in bowel habits
Differentials for Erythema Nodosum
Differentials for pyoderma gangrenosum
UC vs Crohn’s (simply)
What are the extra-intestinal features of IBD?
Multi-systemic causes of clubbing
Acute treatment of Crohn’s
Long term Crohn’s treatment
Azathioprine
MoA
Drug interaction with?
Azathioprine
MoA: inhibition of purine synthesis → inhibits cell proliferation (particularly lymphocytes)
Interaction with: Allopurinol
Azathioprine
- what bloods to do before starting it?
Azathioprine
Bloods before: TMPT (Thiopurine methyltransferase)→ to look for increased risk of azathioprine toxicity
SEs of Azathioprine
- Bone marrow depression
- Nausea/vomiting
- Pancreatitis
- Increased risk of skin cancer (non-melanoma)
