Medications & Dosages Flashcards
Acetaminophen
Adult. Give 15 mg/kg orally; Maximum dose is 1 g | Paediatric. Fibrile Siezures: Give 15 mg/kg; Maximum dose is 650 mg; orally/PR/IV/IO
AcetaZOLAMIDE (Diamox, Diamox Sequels)
Adult. Tx of Acute Mountain Sickness: 250mg orally every 12 hours is recommended | Paediatric. Tx of Acute Mountain Sickness: 2.5mg/kg orally every 12 hours (max dose 250mg/dose) is recommended
Acetic Acid (Vinegar)
Adult and Paediatrics. Position the patient on the side with the affected ear uppermost; Instill 4 to 6 drops into the external ear, and repeat every 2 to 3 hours | For jellyfish stings outside the US, rinse the area with vinegar for 30 seconds to limit the discharge of unfired nematocysts remaining on the skin
Acetylcysteine (Mucomyst, Acetadote)
Adult and Paediatrics. Acetaminophen OD: Loading dose 150 mg/kg IV, mix in 200 mL of D5W and infuse over 1 hour; then 50 mg/kg IV in 500 mL of D5W and infuse over 4 hours | If IV access is not available, give 140 mg/kg orally
Activated charcoal
Adult and Paediatric older than 1 year. 25 to 100 g | Paediatric younger than 1 year. 1 g/kg
Adenosine (Adenocard)
Adult. 6-mg rapid IV/IO bolus over 1 to 3 second followed by a 10-mL saline flush; Additional 12-mg dose if needed after 1 to 2 minutes over the same time frame; Maximum total dosage is 30 mg | Paediatric . Initial dose 0.1 mg/kg (max first dose of 6mg) rapid IV/IO push over 1 to 3 seconds followed by a 5- to 10-mL saline flush; Second dose 0.2 mg/kg (max second dose of 12mg) rapid IV/IO push followed by a 5- to 10-mL saline flush
Albumin (Albumarc, Albutein, Flexbumin)
Dose rate adjust to pt needs
Albuterol
Adult. Respiratory distress: 2.5 to 5 mg via nebulizer or 1 to 2 inhalations (90 to 180 mcg) by MDI ; Respiratory distress with signs of bronchospasm: 5 mg via nebulizer or 6 puffs via MDI ; Hyperkalemia: 5 mg via nebulizer| Paediatric. Mild to moderate asthma, anaphylaxis, hyperkalemia: 4 to 8 puffs with MDI every 20 minutes with a spacer ; Weighs less than 20 kg (2.5 mg/dose via nebulizer) or more than 20 kg (5 mg/dose via nebulizer) ; Respiratory distress with signs of bronchospasm: 5 mg via nebulizer or 6 puffs via MDI
Amiodarone (Cordarone, Pacerone)
Adult. Initial dose 300 mg IV/IO push ; Second dose 150 mg IV/IO push ; Loading dose 150 mg IV/IO over 10 minutes ; Max cumulative dose of 2.2 g IV/IO per 24 hours | Paediatric. Refractory VF/pulseless VT: 5 mg/kg IV/IO bolus ; can repeat if needed to max cumulative dose of 15mg/kg IV per 24 hours (2.2g in adolescents per 24 hours) ; Max single dose of 300mg. Poor perfusing ventricular or atrial sysrhythmias: loading dose 5mg/kg IV/IO over 20 to 60 minutes (max single dose of 300mg) ; can repeat if needed to max cumulative dose of 15mg/kg IV per 24 hours (2.2g in adolescents per 24 hours)
Aspirin (Acetylsalicylic Acid)
Adult. 162 mg to 325 mg orally (chewable) | Paediatric. Not recommended
Atropine sulfate
Adult. Symptomatic bradycardia: 0.5 to 1 mg IV/IO every 3 to 5 minutes as needed (maximum of 3 mg) ; Acetylcholinesterase inhibitor poisoning: Extremely large doses (2 to 4mg or higher) may be needed | Paediatric. Symptomatic bradycardia: 0.02 mg/kg IV/IO; max single dose 0.5mg; total max dosing of 1 mg (child) and 3 mg (adolescent) ; ET dose. 0.04 to 0.06 mg/kg | Child Younger Than 12. Acetylcholinesterase inhibitor poisoning: 0.05 mg/kg initially, then repeat and double the dose every 5 minutes until muscarinic sxs reverse | Child Older Than 12. Acetylcholinesterase inhibitor poisoning: 1mg initially, then repeat and double the dose every 5 minutes until muscarinic sxs reverse | Paediatric RSI. IV/IO: 0.01 to 0.02 mg/kg (max dose of 0.5 mg) ; IM. 0.02 mg/kg
Benzocaine Spray (Hurricane)
Adult. 0.5- to 1-second spray; Repeat as needed | Paediatric. 0.25- to 0.5-second spray; Repeat as needed
Bumetanide (Bumex)
Adult. 0.5 to 1 mg IV slowly over 1 to 2 minutes or IM | Paediatric. Not recommended for children younger than 12 years due to limited research; consult Medical Command
Calcium chloride
Adult. Calcium channel blocker OD and Hyperkalemia: 500 to 1,000 mg slow IV/IO push over 5 minutes; repeat if needed | Paediatric. Calcium channel blocker OD, Hypocalcemia, and Hyperkalemia: 20 mg/kg slow IV/IO push; Maximum dose: 1 g (10 mL); May repeat the dose if documented or suspected clinical indication persists
Calcium gluconate
Adult. Calcium channel blocker OD and Hyperkalemia: 1.5 to 3 g (15 to 30 mL of 10% solution) slow IV/IO push over 5 minutes | Paediatric. Calcium channel blocker OD, Hypocalcemia, and Hyperkalemia: 60 mg/kg slow IV/IO push over 10 minutes; May repeat the dose if documented or suspected clinical indication persists | Adults and Paediatrics. Hydrofluoric Acid Burn Management: Apply generous amounts of topical gel to the exposed burned skin area, and leav in place for at least 20 minutes; reasses after
Cimetidine (Tagamet)
Adult. 400 mg orally four times daily; Maximum is 1,200 mg/day | Paediatric. Use is NOT recommended; 20 to 40 mg/kg per day in divided doses; maximum is 40mg/kg perday for most indications
Hetastarch (Hespan)
Titrate according to the patient’s physiologic response
Plasma Protein Fraction (Plasmanate)
Titrate according to the patient’s hemodynamic response | In the management of shock secondary to burns, the physician’s orders regarding the administration rate must be closely followed | The medical control physician uses standard formulas to determine the correct rate of IV administration
0.9% Sodium Chloride (Normal Saline)
Infusion rate will depend on the specific situation being treated.
0.45% Sodium Chloride
The specific situation and patient condition will dictate the rate at which one-half normal saline is administered
Lactated Ringer Solution (Hartmann Solution)
Hypovolemic shock: titrate according to the patient’s physiologic response | Hypoperfusion: 20 mL/kg IV/IO over 15 minutes; repeat as needed for ongoing hypoperfusion
3% Sodium Chloride (Hypertonic Saline)
Infusion rate will depend on the specific situation being treated
5% Dextrose in 0.45% Sodium Chloride
Infusion rate will depend on the specific situation being treated
5% Dextrose in 0.9% Sodium Chloride
Infusion rate will depend on the specific situation being treated
5% Dextrose in Lactated Ringer Solution
Infusion rate will depend on the specific situation being treated
Total Parenteral Nutrition
Vary based on the specific mixture
Dexamethasone sodium phosphate (Decadron)
Adult. AMS tx: Give 4 mg IM, IV, or orally every 6 hours, until sxs resolve ; HACE: 8 mg IM, IV, or orally, followed by 4 mg IM, IV, or orally every 6 hours, until sxs resolve ; Bronchospasm: 0.6 mg/kg IM, IV, or orally (16 mg maximum) | Paediatric. AMS and HACE tx: 0.15 mg/kg IM, IV, or orally every 6 hours (4 mg/dose maximum) ; croup tx: 0.6 mg/kg orally, IM, IV, or IO given once (16 mg maximum) ; asthma tx: 0.6 mg/kg IM, IV, or IO every 24 hours (16 mg maximum)
Dextran
Titrate according to the patient’s physiologic response
Bacteriostatic Water
According to the drug manufacturer’s recommendations
5% Dextrose in Water
Usually administered through a minidrip (60 drops/mL) set at a TKO (to keep open) rate
10% Dextrose in Water
Infusion rate is usually dependent on the patient’s condition
Dextrose
Adult. 25 g of D10W to D50W IV ; May be repeated as necessary mental status improved or maximum field dosage is reached | Paediatric. 0.5 to 1 g/kg of D10W to D25W slow IV/IO push ; May be repeated as necessary mental status improved or maximum field dosage is reached | Neonates and infants. 0.2 g/kg, followed by 5 mL/kg/h D10W IV/IO infusion
Diazepam (Valium, Diastate, AcuDial)
Adult. shivering associated w/ hyperthermia/heat-exposure: 2 mg IV/IO; may repeat once in 5 minutes ; Chemical restrain: 5 mg IV or 10 mg IM | Paediatric. Seizure activity: 0.1 mg/kg slow IV or IO (4 mg maximum) ; shivering associated w/ hyperthermia/heat-exposure: 0.1 mg/kg IV/IO (2.5 mg maximum single dose) - may repeate once for total max dose of 5mg IV/IO or 0.5mg/kg PR (max single dose of 10mg) - other repeats noted for PR only ; Chemical restrain: 0.05 to 0.1 mg/kg IV (5 mg maximum) or 0.1 to 0.2 mg/kg IM (10 mg maximum
Digoxin (Lanoxin)
(not listed per textbook)
Diltiazem (Cardizem, Dilacor, Diltiaz)
Adult. Initial dose: 15 to 20 mg (0.25 mg/kg) IV/IO slowly over 2 minutes ; After 15 minutes: a second bolus of 20 to 25 mg (0.35 mg/kg) IV/IO can be given slowly over 2 minutes ; Patients older than age 65: require a maximum initial dose of 10 mg IV/IO and second dose of 20 mg IV/IO ; Maintenance infusion: 5 to 15 mg/h titrated to a physiologically appropriate heart rate | Paediatric. Not recommended
DiphenhydrAMINE HCl (Benadryl)
Adult. Urticaria or pruritus, anaphylaxis, or allergic reaction: 1 mg/kg up to maximum 50-mg dose IM, IV, or orally - IV prefered for shock ; Antiemetic: 12.5 to 25 mg IV/IM or orally ; Dystonic/extrapyramidal symptoms: 25 to 50 mg IV/IM | Paediatric. Urticaria or pruritus, anaphylaxis, or allergic reaction: 1 mg/kg up to maximum 50-mg dose IM, IV, or orally ; Antiemetic w/ Older than age 2 and weight greater than 12 kg: 0.1 mg/kg IV (maximum: 25 mg) ; Dystonic/extrapyramidal symptoms: Give 1 to 1.25 mg/kg IV/IO or IM (25 mg maximum single dose) ; Chemical restraint: Give 1 mg/kg IM/IV or orally (25 mg maximum dose)
DOBUTamine Hydrochloride (Dobutrex)
Adult. IV infusion at 2 to 20 mcg/kg/min titrated to desired effect | Paediatric. IV infusion at 2 to 20 mcg/kg/min titrated to desired effect
DOPamine Hydrochloride (Intropin)
Adult. IV/IO infusion at 5 to 20 mcg/kg/min, slowly titrated to patient response | Paediatric. Safety and effectiveness in children have not been established
Droperidol (Inaspine)
Adult. Chemical restraint: 2.5 mg slow IV or 5 mg IM | Paediatric. Not routinely recommended
EPINEPHrine
Adult. Anaphylaxis: 0.3 mg IM in the anterolateral thigh ; Additional epinephrine can be administered every 5 to 15 minutes ; If wheezing is present: give nebulized albuterol and/or 5 mL of 1 mg/mL epinephrine nebulized ; If stridor is present: consider 5 mL of 1 mg/mL epinephrine nebulized ; Severe bronchoconstriction with impending respiratory failure: 0.01 mg/kg of 1 mg/mL IM (0.3 maximum) ; (An epinephrine IV infusion can be given when cardiovascular collapse is present) ; Profound bradycardia with signs of hemodynamic instability: IV/IO infusion of 0.02 to 0.2 mcg/kg/min titrated to a mean arterial pressure greater than 65 mm Hg or IV/IO push dose 10 to 20 mcg boluses every 2 minutes titrated to a mean arterial pressure greater than 65 mm Hg ; Shock unresponsive to IV fluids, or cardiogenic shock with signs of fluid overload: IV/IO infusion 0.05 to 0.3 mcg/kg/min ; Cardiac arrest: Give 1 mg (0.1 mg/mL) IV/IO every 3 to 5 minutes during resuscitation. Follow each dose with a 20-mL flush and elevate arm for 10 to 20 seconds after dose ; ET: 2 to 2.5 mg diluted in 10 mL NS | Paediatric. Anaphylaxis: (If weight is less than 25 kg) give 0.15 mg IM in the anterolateral thigh, (if weight is 25 kg or more) give 0.3 mg IM in the anterolateral thigh ; Additional epinephrine can be administered every 5 to 15 minutes ; If wheezing is present: give nebulized albuterol and/or 5 mL of 1 mg/mL epinephrine nebulized ; If stridor is present: consider 5 mL of 1 mg/mL epinephrine nebulized ; (An epinephrine IV infusion can be given when cardiovascular collapse is present) ; Profound bradycardia with signs of hemodynamic instability: IV/IO infusion of 0.01 mg/kg every 3 to 5 minutes (10 mcg maximum) ; Cardiac arrest: Give 0.01 mg/kg (0.1 mg/mL) IV/IO every 3 to 5 minutes during arrest (1 mg maximum) ; ET: 0.1 mg/kg (1mg/mL) IV/IO every 3 to 5 minutes during arrest (1 mg maximum dose)