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BCPP 2023 francais > Médicaments et Cytochromes > Flashcards

Médicaments et Cytochromes Flashcards

1
Q

Citalopram et escitalopram

A

2C19 et 3A4

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2
Q

Sertraline

A

3A4

inhibe 2d6 faible

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3
Q

Paroxetine

A

2D6

inhibe 2D6

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4
Q

Fluoxetine

A

varié

Inhibe 2c19 et 2D6

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5
Q

Fluvoxamine

A

1a2 et 2d6 mineur

Inhibe 1A2 et 2C19

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6
Q

Venlafaxine

A

2D6

inhibe 2d6 faible

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7
Q

Duloxetine

A

1A2 et 2D6

inhibe 2D6 modéré

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8
Q

Levomilnancipran

A

3A4

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9
Q

trazodone

A

3A4

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10
Q

bupropion

A

2B6 et varié

Inhibe 2D6

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11
Q

Mirtazapine

A

3A4

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12
Q

Clozapine et olanzapine

A

1A2

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13
Q

Quétiapine

A

3A4

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14
Q

Rispéridone

A

2D6 et 3A4

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15
Q

Aripiprazole et brexpiprazole

A

2D6 et 3A4

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16
Q

Cariprazine

A

3A4

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17
Q

Asenapine

A

1A2

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18
Q

Ziprasidone

A

1a2 et 3a4 mineur

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19
Q

Haldol

A

2D6 et 3A4

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20
Q

Clomipramine

A

1A2 et 2D6

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21
Q

Imipramine

A

2D6

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22
Q

Amitriptyline, nortriptyline, doxepine et desipramine

A

variés mais 2D6 en majeurs

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23
Q

vilazodone

A

3A4

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24
Q

nefazodone

A

inhibe 3A4

PTSD 3d ligne, hepatotox, bien toléré (poids, sexuel et somnolence)

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25
Q

Methylphenidate

A

Inconnu

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26
Q

Dextroamphetamine

A

2D6

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27
Q

Guanfacine

A

3A4

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28
Q

Atomoxetine

A

2D6

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29
Q

Viloxazine

A

Inhibe 1A2

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30
Q

Clonidine

A

inconnu

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31
Q

Lithium

A

rénal

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32
Q

Acide valproique

A

varié

33
Q

Lamotrigine

A

UGT

34
Q

Topiramate

A

Inconnu

35
Q

Carbamazépine

A

3A4

Induit 1A2, 2B6, 2C9, 3A4

36
Q

Oxcarbazépine

A

3A4

Induit 3A4 (faible)

37
Q

clonazepam

A

3A4

38
Q

Lorazepam, oxazepam, temazepam

A

aucun

temazepam 3a4 mineur

39
Q

Diazepam

A

2C19 et 3A4

40
Q

Buspirone

A

3A4

41
Q

Hydroxyzine

A

inconnu

42
Q

benadryl

A

inhibe 2d6 (faible)

43
Q

ketamine

A

2B6 et 3A4

44
Q

Esketamine

A

2B6

45
Q

donepezil

A

2D6 et 3A4 mineur

46
Q

galantamine

A

2D6 et 3A4 mineur

IRC, diminuer dose a 16mg si 10 a 60ml/min
éviter si inférieure a 10 ml/min

47
Q

memantine

A

pas CYP

Dose normale 5mg a titrer ad 20mg
IRC 30 a 50, envisager diminuer dose
IRC - de 30, max 10mg par jour

48
Q

rivastigmine

A

Inconnu

IRC: inférieur a 50, attention pout les caps
timbre pas d’ajustement

49
Q

Pimozide

A

2D6 et 3A4

indiqué pour tourette et tics (2e ligne avec haldol)

50
Q

benztropine

A

2d6 mineur

51
Q

Valbenazine

A

2D6 et 3A4

52
Q

tetrabenazine

A

2D6

53
Q

naltrexone

A

inconnu

54
Q

zopiclone, eszopiclone, zolpidem et zaleplon

A

3A4

55
Q

lemborexant

A

3A4

induit 2B6 faible

56
Q

suvorexant

A

3A4

57
Q

modafinil

A

3A4

induit 2c19 (léger) et 3A4 (modéré)

58
Q

prazosin

A

inconnu

indiqué PTSD mais pas approuvé FDA

59
Q

propranolol

A

1A2 et 2D6

inhibite 1A2 (faible)

60
Q

vortioxetine

A

2D6 majeur
multiples mineurs.

61
Q

lumateperone

A

3A4

62
Q

levodopa/carbidopa

A

inconnu

63
Q

bromocriptine

A

3A4

64
Q

ropinirole

A

1A2

65
Q

Rotigotine

A

inconnu

66
Q

ramelteon

A

1A2, 2C9, 3A4

agoniste des récepteurs de la mélatonine

indiqué pour insomnie (onset)

67
Q

Tasimelteon

A

1A2 et 3A4

Agoniste des récepteurs de la mélatonine

Indiqué pour non-24h sleep wake disorder.

68
Q

Solriamfetol

A

aucun

indiqué pour somnolence excessive associé a la narcolepsie ou apnée du sommeil.

69
Q

Pitolisant

A

2D6 et 3A4

Narcolepsie (somnolence excessive et cataplexie)

70
Q

Sels d’oxybate

A

inconnu

Indiqué pour
-narcolepsie (cataplexie ou somnolence excessive).
-Hypersomnie idiopathique.

71
Q

Acamprosate

A

Inconnu

Indiqué pour Dépendance a l’alcool

72
Q

Disulfiram

A

multiple mineur
inhibe 2E1 FORT

Pour renforcer la sobriété chez patient alcooliques

73
Q

Naltrexone

A

inconnu

74
Q

Buprenorphine

A

3A4

75
Q

Methadone

A

2B6 et 3A4

76
Q

Lofexidine

A

2D6

indiqué pour réduire les symptomes de sevrage aux opiacés pour facilité l’arrêt abrupt.

77
Q

nicotine

A

multiples mineurs

78
Q

varenicline

A

non CYP

BCPP 2023 francais (10 decks)

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