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pharm > med list 1 > Flashcards

med list 1 Flashcards

1
Q

Amiodarone (Cordarone) class

A

antiarrhythmias- potassium channel blockers

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2
Q

Amiodarone (Cordarone) MOA

A

acts directly on heart muscle cells to prolong repolarization and the refractory period, increasing the threshold for ventricular fibrillation; also acts on peripheral smooth muscle to decrease peripheral resistance

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3
Q

Apresoline (hydralazine) class

A

antihypertensive-vasodilator

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4
Q

Apresoline (hydralazine) MOA

A

Direct-acting peripheral arteriolar vasodilator.

Lowering of BP in hypertensive patients and decreased afterload in patients with HF.

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5
Q

Aspirin (As part of MONA) class

A

anticoagulant
salicylates
for angina

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6
Q

Aspirin (As part of MONA) MOA

A

Produce analgesia and reduce inflammation and fever by inhibiting the production of prostaglandins.
Decreases platelet aggregation.
for angina

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7
Q

Cardizem (diltiazem) class

A

antihypertensive- calcium channel blocker

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8
Q

Cardizem (diltiazem) MOA

A

block the calcium channels in the specialized tissue of muscle cells of the heart and in the smooth muscle cells in the walls of blood vessels.

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9
Q

Catapress patch class

A

antihyertensive-vasodilator alpha adrenergic blocker

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10
Q

Catapress patch MOA

A

block alpha receptors that mediate vasomotor tone

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11
Q

Digoxin (lanoxin) class

A

antiarrhythics- cardiac glycoside

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12
Q

Digoxin (lanoxin) MOA

A

Increases the force of myocardial contraction.
Prolongs refractory period of the AV node.
Decreases conduction through the SA and AV nodes

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13
Q

Glucophage (metformin) class

A

biguanide- diabetic agent

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14
Q

Glucophage (metformin) MOA

A

Decrease intestinal absorption of glucose; Increase use of glucose by muscle and fat cells. Decrease hepatic glucose production

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15
Q

Isordil class

A

antianginal-nitrate

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16
Q

Isordil MOA

A

Dilates coronary arteries, veins arteries.

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17
Q

Lasix furosemide class

A

diuretic- loop diureic

18
Q

Lasix furosemide MOA

A

act on the loop of henle to inhibit sodium and chloride reabsorption; vasodilation

19
Q

Lopressor (metoprolol) class

A

antihypertensive- beta blocker

20
Q

Lopressor (metoprolol) MOA

A

Leads to a decrease in heart rate and strength of contraction as well as vasodilatation

21
Q

Mannitol class

A

diuretic agents-osmotic diuretic

22
Q

Mannitol MOA

A

Produce rapid diuresis by increasing the solute load (osmotic pressure) of the glomerular filtrate which then causes tubular reabsorption of water; this leads to an increase of urine output.

23
Q

Morphine (As part of MONA) class

A

opioid analgesic-opiod agonist

24
Q

Morphine (As part of MONA) MOA

A

Binds to opiate receptors in the CNS. Alters the perception of and response to painful stimuli while producing generalized CNS depression.
for angina

25
Q

Nitroglycerine class

A

antianginal-nitrate

26
Q

Nitroglycerine MOA

A

Increases coronary blood flow by dilating coronary arteries and improving collateral flow to ischemic regions.
Produces vasodilation (venous greater than arterial).
Decreases left ventricular end-diastolic pressure and left ventricular end-diastolic volume (preload).
Reduces myocardial oxygen consumption.

27
Q

Prednisone class

A

anti-inflammatory steroid immunosuppressant

28
Q

Prednisone MOA

A

Suppression of inflammation and modification of the normal immune response.

29
Q

Solu-medrol class

A

anti-inflammatory corticosteroid immunosuppressant

30
Q

Solu-medrol MOA

A

Suppression of inflammation and modification of the normal immune response.
Replacement therapy in adrenal insufficiency.

31
Q

SSKI class

A

antithyroid agent-iodide

32
Q

SSKI MOA

A

Reduce size and vascularity of thyroid gland
Rapidly inhibits the release and synthesis of thyroid hormones.
Decreases the vascularity of the thyroid gland.
Decreases thyroidal uptake of radioactive iodine following radiation emergencies or administration of radioactive isotopes of iodine.
Iodine is a necessary component of thyroid hormone.

33
Q

Synthroid (levothyroxine) class

A

thyroid hormone

34
Q

Synthroid (levothyroxine) MOA

A

Replacement in hypothyroidism to restore normal hormonal balance.
Replacement of or supplementation to endogenous thyroid hormones

35
Q

Transderm-Nitro patch class

A

antianginal-nitrate

36
Q

Transderm-Nitro patch MOA

A

Dilates coronary arteries, veins arteries.

37
Q

Vasotec (enalapril) class

A

antihypertensive-ACE inhibitor

38
Q

Vasotec (enalapril) MOA

A

Decreases the formation of angiotensin II. Also decreases the secretion of aldosterone

39
Q

Zocor (simvastatin) class

A

antilipemics-statins

40
Q

Zocor (simvastatin) MOA

A

block the last step in the formation of cholesterol

increase number of LDL receptors

pharm (16 decks)

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