Med Cards: WEEK 7 Flashcards
Atorvastatin
lipid-lowering agents (statin)
Atorvastatin: Expected pharmacological action
inhibits an enzyme which is responsible for catalyzing, an early stage in synthesis of cholesterol
Atorvastatin: therapeutic use
lowering of total and LDL cholesterol and triglycerides. Slightly increase the HDL cholesterol
Atorvastatin: Complications
arrhythmias, hypoglycemia, hepatic failure, hepatitis, pancreatitis, rectal hemmorrhage, rhabdomyolysis, anaphylaxis, flu-like symptoms, rash, abdominal pain, constipation, gas, confusion, leg cramps
Medication Administration: Atorvastatin
PO, can take with or without food
adults: 10-20 mg ONCE daily initially then increased according to lipid level. maintenance at 10-80 ONCE daily
Atorvastatin: Contraindications
active hepatic disease, breastfeeding, hypersensitivity to atorvastatin or its components, pregnancy, unexplained persistent rise in serum transaminase level, alcoholism
not recommended to kids under the age of 8
Atorvastatin: Interactions
grapefruit juice can cause adverse reactions.
oral contraceptives and digoxin
Atorvastatin: evaluation of medication effectiveness
decrease in LDL and total cholesterol levels
Atorvastatin: Nursing interventions
monitor liver functions prior as clinically indicated
Atorvastatin: Client Education
advise client to not drink alcohol, have low cholesterol diet, get good exercise, and notify PCP of legs and ABD cramps
stop taking if pregnant
Lisinopril
ACE Inhibitor
Lisinopril: Expected pharmacological action
lower blood pressure by inhibiting conversion of angiotensin to angiotensin ll
basically, to treat hypertension
Lisinopril: Medication administration
PO
adult: 5 mg initially (if taking diuertic) and 10 mg (if not taking diuretic) ONCE daily
maintenance: 20-40 mg ONCE daily
max: 80 mg ONCE daily
Lisinopril: Therapeutic Use
antihypertensive and heart failure
Lisinopril: Interactions
NSAIDS: decrease antihypertensive medications
also, lithium, K+ salts, herbal and K+ supplements, pain and inflammation drugs, other antihypertensives, insulin
Lisinopril: Complications
arrhythmias, hypotension, MI, acute renal failure, pulmonary embolism, HYPERKALEMIA, hyponatremia, cough, orthostatic hypotension, edema, rash, drowsiness, weakness
Lisinopril: Contraindications
diabetes, history of angioedema, hypersensitivity to lisinopril, other ACE inhibitors, hypotension
Lisinopril: Evaluation of Medication Effectiveness
Blood pressure will return to normal limits
Lisinopril: Nursing interventions
monitor BP for 2 hrs after start of treatment
Lisinopril: Client education
get up/change slowly
take as directed
avoid K+ diet