MBChB List Doses Flashcards
Acyclovir for genital herpes simplex suppression
400 mg bd
Acyclovir for nongenital herpes simplex treatment
200 mg 5x 5/7
Acyclovir for first-episode genital herpes simplex treatment
200 mg 5x
Acyclovir for recurrent genital herpes simplex
800 mg tds 2/7
Acyclovir for Varicella zoster/Herpes Zoster treatment in adults
800 mg 5x 7/7
Acyclovir for Herpes Zoster/Varicella-Zoster encephalitis
10 mg/kg
every 8 hours
10-14 days
Adrenaline for CPR
1 in 10 000
1 mg Q3-5 minutes IV
Adrenaline for Acute anaphylaxis
500 micrograms IM Q5 minutes
Alendronate for postmenopausal osteoporosis
10 mg OD
70 mg once weekly
Alendronate for the treatment of osteoporosis in men
10 mg OD
Alendronate for prevention/treatment of corticosteroid-induced osteoporosis in postmenopausal women
10 mg OD
Allopurinol for gout prophylaxis (initial dose)
100 mg OD
Allopurinol for gout prophylaxis (maintenance in mild gout)
100-200 mg OD
Allopurinol for gout prophylaxis (maintenance in moderately severe gout)
300-600 mg divided doses
Allopurinol for gout prophylaxis (maintenance in severe gout)
700- 900 mg OD
Amiodarone for treatment of arrhythmias
200 mg tds 7/7 then 200 mg bd 7/7 then 200 mg OD
Amiodarone for CPR (VF, pulsless VT refractory to defibrillatrion)
300 mg IV
Augmentin for beta-lactamase-producing strains
250/125 mg Q8h
IV 1.2g Q8
Augmentin for acute diverticulitis
500/125 mg tds 5/7
IV 1.2 g Q8h
Augmentin for a diabetic foot infection
500/125 mg Q8
1.2g Q8h
Augmentin for leg ulcer infection
500/125 mg Q8 7/7
IV 1.2 g Q8h
Augmentin for cellulitis/erysipelas
500/125 mg Q8h 7/7
IV 1.2g Q8h
Augmentin for surgical prophylaxis
IV 1.2 g 30 minutes before then Q8h for 2-3 doses in high-risk procedures
Augmentin for community-acquired pneumonia
500/125 tds 5/7
IV 1.2g Q8
Augmentin for hospital-acquired pneumonia
500/125 mg tds 5/7
Augmentin for acute exacerbation of bronchiectasis
500/125 mg tds 7-14/7
1.2g Q8h
Augmentin for acute exacerbation of COPD
500/125 mg tds 5/7
IV 1.2 g Q8h
Augmentin for acute sinusitis
500/125 mg tds 5/7
Augmentin for pyelonephritis/catheter-associated UTI
500/125 mg tds 7-10/7
IV 1.2g Q8h
Aspirin for secondary prevention of CVD
75 mg OD
Aspirin for management of NSTEACs or STEMI
300 mg OD until dx established
Aspirin for long term treatment of TIA/ischemic stroke not associated with AF
75 mg OD
Aspirin for treatment of acute ischaemic stroke
300 mg OD for 14 days
Aspirin for mild to moderate pain
300 to 900 mg Q4-6h
Max 4g/day
Aspirin for acute migraine
900 mg OD
Aspirin for prevention of Pre-eclampsia
75-150 mg OD from 12/40 until birth
Aspirin for Mild to moderate pain
300-600 mg Q4-6h max 2.4g/day
Atenolol for Hypertension
25-50 mg OD
Atenolol for Angina
100 mg daily
Atenolol for arrhytmias
50-100 mg OD
Atenolol for migraine prophylaxis
50 to 200 mg
Atropine for bradycardia due to beta blocker OD
3mg
Atropine for insecticide or nerve agent poisoning
2 mg Q5-10 minutes
Atropine for GI symptoms secondary to smooth muscle spasm
0.6- 1.2 mg nocte
Beclomethasone for asthma prophylaxis
200-400 mcg bd
can go to 800 mcg
Beclomethasone for rhinitis
100 mcg bd
to 50 mcg
max 400 mcg
Bendroflumethiazide for oedema
5-10 mg OD then 5-10 mg 1-3 times a week
Bendroflumethiazide for hypertension
2.5 mg OD mane
Benztropine for medication-induced movement disorder
1-4 mg OD or BD
Benztropine for parkinsonism
0.5 to 1 mg increase in 0.5 increments at 5-6 day intervals (1-2 mg OD)
Max 6 mg/day
Benzylpenicillin for infections
0.6 to 1.2 g Q6h IM/IV
Benzylpenicillin for Endocarditis
1.2g Q4h
Benzylpenicillin for anthrax
2.4g Q4h
Benzylpenicillin for GB prophylaxis in labor
3g then 1.5g Q4
Benzylpenicillin for meningicoccal disease
2.4 g Q4h IV
Benzylpenicillin for suspected meningicoccal disease
1.2 g IV/IM before transfer
Bezafibrate for mixed hyperlipidaemia if statin contraindicated or not tolerated
200 mg tds
SR 400 mg OD
Budesonide for prophylaxis of mild to moderate asthma
200-400 mcg OD
Budesonide for asthma prophylaxis
100-800 mcg BD
Budesonide for rhinitis
128 mcg OD
64 mcg BD
Budesonide for nasal polyps
100 mcg BD for 3/12
Carbamazepine for tonic-clonic seizures
100 to 200 mg 1-2x increased in steps of 100-200 mg every 2 weeks
usual dose 0.8 to 1.2 g daily
Carbamazepine for trigeminal neuralgia
100 mg 1-2x up to 200 mg 3-4 times
Carbamazepine for Bipolar prophylaxis unreponsive to lithium
400-600 mg
Carbamazepine for diabetic neuropathy
100 mg 1-2x increase to response
to 200 3-4 x
Carbimazole for hyperthyroidism
15-40 mg OD till euthyroid
Cefazolin for surgical prophylaxis
1 g 30-60 minutes before then 0.5-1g during
Cefazolin for skin, bone, and joint infection
1-2 g daily
Cetirizine for allergy relief
10 mg OD
Colecalciferol for prevention of vitamin D deficiency
400 units OD
Colecalciferol for treatment of vitamin D deficiency
800 units OD
Ciprofloxacin for Acute otitis externa
0.25 mL bd 7/7
Ciprofloxacin for moderate to severe diabetic foot disease
500 mg BD
IV 400 mg Q8-12h over 60 minutes
Ciprofloxacin for fistulating Crohns disease
500 mg BD
Ciprofloxacin for respiratory tract infections
500 to 750 mg BD
400 mg Q8-12h over 60 minutes
Ciprofloxacin for Pseudomonal LRTI in CF
750 mg BD
Ciprofloxacin for UTI
250-750 mg BD
IV 400 mg Q8-12h over 60 minutes
Ciprofloxacin for prostatitis
500 mg BD 14/7
IV 400 mg Q8-12h
Ciprofloxacin for uncomplicated gonorrhea
500 mg One dose
Ciprofloxacin for disseminated gonococcal infection
IV 500 mg Q12h 7/7
PO 500 mg BD following IV treatment
Ciprofloxacin for infections
500 to 750 mg BD
IV 400 mg Q8-12h over 60 minutes
Ciprofloxacin for Surgical prophylaxis
750 mg 60 minutes before
Ciprofloxacin for anthrax
500 mg BD
IV 400 mg Q12h over 60 minutes
Ciprofloxacin for acute pyelonephritis/catheter-associated UTI
500 mg BD 7/7
IV 400 mg Q8-12h
Clopidogrel for prevention of atherothrombotic events in PCI
300 mg loading dose
Clopidogrel for cerebrovascular event and contraindication to aspirin
75 mg OD
Clopidogrel for prevention of atherothrombotic event in PVD or following MI/stroke
75 mg OD
Clopidogrel for prevention of atherothrombotic event in NSTEMI
300 mg then 75 mg OD up to 12/12
Clopidogrel for prevention of atherothrombotic event in STEMI
300 mg then 75 mg
>76 yo 75 mg for at least 4 weeks
Clopidogrel for prevention of atherothrombotic event in patients with AF and cannot take warfarin
75 mg OD
Codeine for acute diarrhea
30 mg 3-4x
usual dose 15-60 mg 3-4x
Codeine for mild to moderate pain
30-60 mg Q4h max 240 mg
IM 30-60 mg Q4h
Colchicine for Acute gout
500 mg 2-4x
max 6g
Colchicine for short term prophylaxis of gout
500 mg bd
Cyclizine for nausea, vomiting, vertigo, motion sickness, labyrinthine disorders
50 mg up to 3x
IV 50 mg tds
Cyclizine for nausea and vomiting in palliative care
150 mg SC
50 mg up to 3x
Dabigatran for VTE prophylaxis following knee replacement
110 mg 1-4 hours after surgery, 220 mg OD 10/7
>75 yo 75 mg 1-4 hours after surgery then 150 mg OD for 10/7
Dabigatran for VTE prophylaxis following hip replacement
110 mg 1-4 hours after surgery,
220 mg OD 28-35/7
> 75 yo
75 mg 1-4 hours after surgery
then 150 mg OD for 28-35/7
Dabigatran for treatment of DVT, OE
150 mg bd
>75 110-150 mg BD
>80 110 mg bd
Dabigatran for stroke/embolism prophylaxis in non-valvular AF
150 mg bd
>75 110-150 mg bd
>80 110 mg bd
Dexamethasone for suppression of allergic/inflammatory disorders
0.5-10 mg OD
Dexamethasone for mild croup
Child
150 mcg/kg
Dexamethasone for severe croup
Child
150 mcg/kg
then 150 mcg/kg IV
then 150 mcg/kg IV if needed
Dexamethasone for bacterial meningitis
IV 8.3 mg Q6h 4/7
Dexamethasone for cerebral edema
8-16 mg then 5 mg IM or IV Q6h
Diazepam for muscle spasm
2-15 mg daily
Diazepam for acute muscle spasm
IM/IV 10 mg then 10 mg ater 4 hours
Diazepam for tetanus
IV 100-300 mg/kg Q1-4h
Diazepam for anxiety
2 mg tds then 15-30 mg if needed
1 mg tds for elderly
Diazepam for insomnia and anxiety
5-15 mg OD nocte
Diazepam for severe anxiety/panic attack/acute alcohol withdrawal
10 mg the 10 mg after 4 hours IV/IM
Diazepam for status epilepticus
10 mg then 10 mg after 10 minutes at 1 mL per minute
Diclofenac for pain and inflammation in rheumatic/MSK disorders
75-150 mg in 2-3 doses
Diclofenac for acute gout
75-150 mg in 2-3 doses
Diclofenac for postoperative pain
75-150 mg in 2-3 doses
Diclofenac for migraine
50 mg at the onset of migraine then 50 mg after 2 hours then 50 after 4-6 hours max 200 mg
Digoxin initial dose for atrial fibrillation or flutter
0.75-1.5 mg over 24 hours
Digoxin maintenance dose for AF or flutter
125 to 250 mcg
Digoxin for heart failure
62.5-125 mcg OD
Digoxin in emergency AF or flutter
the loading dose of 0.75-1 mg over 2 hours
Diltiazem for angina
60 mg tds max 360 mg/day
elderly 60 bd max 360 mg/day
Docusate sodium for chronic constipation
up to 500 mg in divided doses
PR 120 mg
Domperidone for nausea and vomiting
> 35 kg weight
10 mg up to 3x
max 30 mg
Doxycycline for chlamydia, rickettsia, mycoplasma
200 mg in 1-2 doses then 100 mg OD
Doxycycline for severe infections
200 mg OD
Doxycycline for acute sinusitis, cough, community-acquired pneumonia
200 mg one dose
then 100 mg OD 5/7
Doxycycline for hospital-acquired pneumonia
200 mg 1 dose then 100 mg OD 5/7
Doxycycline for acute exacerbation of bronchiectasis
200 mg for one dose, then 100 mg OD 7-14/7
Doxycycline for acute exacerbation of COPD
200 mg for 1 dose then 100 mg OD 5/7
Doxycycline for mild diabetic foot infection
200 mg for 1 dose then 100 mg OD for 7/7
Doxycycline for Cellulitis/erysipelas
200 mg for 1 dose the 100 mg OD for 5-7/7
Doxycycline for leg ulcer infection
200 mg for 1 dose
then 100 mg OD for 7/7
Doxycycline for acne
100 mg OD
Doxycycline for rosacea
100 mg OD
Doxycycline for early syphilis
100 mg BD for 28 days
Doxycycline for neurosyphilis
200 mg BD for 28 days
Doxycycline for uncomplicated genital chlamydia/nongonococcal urethritis
100 mg BD 7/7
Doxycycline for PID
100 mg BD 14/7
Doxycycline for Lyme disease
200 mg in 1-2 divided doses for 21/7
Formoterol for chronic asthma
12 mcg BD
Formoterol for COPD
12 mcg BD max 48 mcg
Ergometrine for PPH due to uterine atony
250-500 mcg IM/slow IV
Erythromycin for infection
250-500 mg qds
- 25 mg/kg Q6h
- 5 mg/kg for severe
Erythromycin for Impetigo
250-500 mg qds 5-7/7
Erythromycin for cellulitis/erysipelas
500 mg qds 5-7/7
Erythromycin for mild diabetic foot infection
500 mg qds 7/7
Erythromycin for leg ulcer infection
500 mg qds 7/7
Erythromycin for community-acquired pneumonia
500 mg qds 5/7
Erythromycin for sore throat
250-500 mg qds 5/7
Erythromycin for early syphilis
500 mg qds 14/7
Erythromycin for uncomplicated genital chlamydia/non-gonococcal urethritis
500 mg bd 14/7
Erythromycin for chronic prostatitis
250-500 mg qds
IV 6.25 mg/kg q6h (12.5 mg/kg for severe infection)
Erythromycin for rosacea
500 mg bd 6-12 weeks
Erythromycin for acne
500 mg bd
ethinylestradiol/levonorgestrel for menstrual symptoms
1 tablet for 21 days, 7 day interval
if started after day 6 of cycle need protection
ethinylestradiol/levonorgestrel for contracpetion
1 tablet for 21 days, same time each day
if started after day 6 of cycle need protection
ethinylestradiol/levonorgestrel for menstrual symptoms 28 days
1 tablet for 21 days 1 inactive tablet for 7 days
if started after day 6 of cycle need protection
ethinylestradiol/levonorgestrel for contraceptions 28 days
1 tablet 21 days, 1 inactive tablet for 7 days
if started after day 6 of cycle need protection
Felodipine for Angina prophylaxis
5 mg OD mane
elderly 2.5 mg OD mane
Felodipine for hypertension
5-10 mg OD mane
elderly 2.5-10 mg OD mane
Fluconazole for candidal balanitis
150 mg for 1 dose
Fluconazole for vaginal candidiasis
150 mg for 1 dose
Fluconazole for recurrent vulvovaginal candidiasis
150 mg every 72 hours for 3 doses then 150 mg once weekly for 6 months
Fluconazole for mucosal candiasis
50 mg OD for 7-14 days
Fluconazole for tinea, pityriasis versiculor, dermal candidiasis
50 mg OD for 2-4 weeks max 6 weeks
Fluconazole for invasive candida infections
400 mg on the first day then 200-400 mg OD
Flumazenil for reversal of benzodiazepines in clinical procedures
200 mcg over 15 seconds then 100 mcg every 1 minute
usual dose 300 to 600 mcg max 1 mg
Fluoxetine for major depression
20 mg OD
increased after 3-4 weeks
max 60 mg OD
Fluoxetine for bulimia
60 mg (40 mg in elderly)
Fluoxetine for OCD
20 mg increased to 60 mg (40 in elderly)
Fluticasone for asthma prophylaxis
100-500 mcg bd
Fluticasone for rhinitis
100 mcg OD
Folic Acid for Anemia
5 mg for 4 months
Folic acid for the prevention of NTDs
400 mcg daily before conception and till week 12
Folic acid for the prevention of NTD in high-risk women
5 mg before conception until 12 weeks
Folic acid for the prevention of methotrexate side effects
5 mg once weekly
Furosemide for oedema
40 mg daily mane then 20-40 mg OD
IV/IM 20-50 mg then increased in steps of 20 mg every 2 hours
Furosemide for resistent oedema
80-120 mg
IM/IV 20-50 mg increased in steps of 20 mg every 2 hours as needed
Furosemide for resistent hypoertension
40-80 mg
IV/IM 20-50 mg then increased in steps of 20 mg as needed
Gabapentin for seizures
300 mg OD on day 1
300 mg BD on day 2
300 mg tds on day 3
then increase in steps of 300 every 2-3 days in 3 divided doses
usual dose 0.9-3.6g
Gabapentin for peripheral neuropathy
300 mg OD on day 1 300 mg BD on day 2 300 mg tds on day 3 then increase in steps of 300 every 2-3 days in 3 divided doses max 3.6g
Gentamicin for a diabetic foot infection
5-7 mg/kg IV adjusted to serum concentration
Gentamicin for leg ulcer infection
5-7 mg/kg IV to serum concentration
Gentamicin for bacterial endocarditis or HACEK endocarditis
IM/IV 1 mg/kg Q12h over at least 3 minutes
Gentamicin for other infections
IV/IM 3-5 mg/kg in 3 divided doses Q8h IV over at least 3minutes
IV 5-7 mg/kg then adjusted to serum concentration
Gentamicin for surgical prophylaxis
1.5 mg/kg IV over 3 minutes 30 minutes before Q8 hourly
Gentamicin for pyelonephritis/catheter-associated UTI
5-7 mg/kg OD then adjusted to serum concentration
Glipizide for type 2 diabetes mellitus
2.5-5mg adjusted to response
Max 20 mg per day
GTN for angina prophylaxis
sublingual 400-800 mcg
GTN for treatment of angina
400-800 mcg Q5min
GTN for unstable angina
IV 10-200 mcg/min max 400 to response
Haloperidol for nausea and vomiting treatment
1-2 mg
elderly 500 mcg
Haloperidol for schizophrenia
2-10 mg daily in 1-2 divided doses
usual dose 2-4 mg daily in 1st episode
up to 10 mg in multiple-episode
(half the lowest adult dose for elderly, max 5 mg)
Haloperidol for acute delirium
1-10 mg in 1-3 divided doses, start at lowest
max 10 mg
elderly half the lowest adult dose, max 5 mg
IM 1-10 mg (500 mcg for elderly)
Haloperidol for manic episodes
2-10 mg in 1-2 divided doses
elderly half the lowest adult dose max 5 mg
Haloperidol for psychomotor agitation
5-10 mg Q12h max 20 mg
elderly 2.5 mg Q12h max 5 mg
IM 5 mg Q1h max 15 mg
elderly 2.5mg Max 5 mg
Enoxaparin for VTE prophylaxis in moderate-risk surgical patients
SC 20 mg 2 hours before surgery
20 mg every 24 hours
Enoxaparin for VTE prophylaxis in high-risk surgical patients
Sc 40 mg 12 hours before surgery
40 mg every 24 hours
Enoxaparin for prophylaxis of DVT in medical patients
40 mg every 24 hours SC
Enoxaparin for treatment of DVT/PE in low risk of recurrence
1.5 mg/kg every 24 hours
Enoxaparin for Treatment of DVT/PE in patients at risk of recurrence
SC 1 mg/kg every 12 hours
Unfractionated Heparin for treatment of PE, unstable angina, and acute peripheral artery occlusion
5000 units loading dose (75 U/kg)
then 18 units/kg/h
Unfractionated Heparin for treatment of severe PE
A loading dose of 10 000 units, then 18 units/kg/h
Unfractionated Heparin for treatment of DVT
IV loading dose 5000 units (75 U/kg) then 18 units/kg/h
Unfractionated Heparin for thromboprophylaxis in medical patients
SC 5000 units Q8-12h
Unfractionated Heparin for thromboprophylaxis in surgical patients
SC 5000 units 1 dose 2 hours before surgery then 5000 units every 8-12 hours
Hydrocortisone for thyrotoxic crisis
IV 100 mg Q6h
Hydrocortisone for acute hypersensitivity
IV 100-300 mg
Hydroxocobalamin for prophylaxis of macrocytic anaemia
IM 1 mg every 2-3 months
Hydroxocobalamin for pernicious anemia without neurological involvement
IM 1 mg three times a week for 2 weeks then 1 mg every 2-3 months
Hydroxocobalamin for pernicious anemia with neurological involvement
IM 1 mg once daily on alternate days till no further improvement
then
1 mg every 2 months
Immediate release Ibuprofen for pain
300-400 mg 3-4x increased to 600 mg 4x
200-400 mg tds
Modified released ibuprofen for pain
1.6 g once daily increased to 2.4 g in 2 divided doses
Immediate release ibuprofen for acute migraine
400-600 mg 1 dose
Ipratropium for reversible airway obstruction
20-40 mcg 3-4x
Ipratropium for COPD
20-40 mcg 3-4x
Ipratropium for acute bronchospasm
Nebulised
500 mcg
Ipratropium for life threatening/severe acute asthma
500 mcg Q4-6h
Isosorbide dinitrate for angina treatment and prophylaxis
30-120 mg in divided doses
IV 1-10 mg/hour
Isosorbide dinitrate for LV failure
40-160 mg in divided doses max 240 mg
IV 2-10 mg/h
Lactulose for constipation
15 mL bd
then
according to response
Lactulose for hepatic encephalopathy
30-50 mL tds adjusted
Levodopa for Parkinsons disease
84 mg inhaled PRN max 5x
Lignocaine/Lidocaine for infiltration anesthesia
max 200 mg
max 500 mg with adrenaline
Lorazepam for anxiety
1-4 mg in divided doses
0.5-2 mg in elderly
Lorazepam for insomnia
1-2 mg nocte
Lorazepam for acute panic attack
IM/IV 25-30 mcg/kg Q6
usual dose 1.5-2.5 mg Q6h
Lorazepam for Seizures
4 mg one dose, then 4mg after 10 minutes
Losartan for diabetic nephropathy
50 mg OD then 100 mg OD if needed
>76 25 mg OD then 100 mg if needed
Losartan for chronic heart failure
12.5 mg OD increased at weekly interval to 150 mg OD
Losartan for hypertension
50 mg OD then 100 mg if needed >76 yo 25 mg OD to 100 mg OD if needed
Magnesium sulfate for severe acute asthma/respiratory deterioration in anaphylaxis
1.2-2g over 20 minutes
Magnesium sulfate for prevention of seizures in pre-eclampsia
4g over 5-15 minutes
then
1g/h for 24 hours
Magnesium sulfate for the treatment of seizures and prevention of recurrence in pre-eclampsia
4g over 5-15 minute then 1g/h for 24 hours after seizure or delivery
Magnesium sulfate for hypomagnesemia
up to 40g over 5 days
maintenance 2.5-5 g daily
usually 3g
Magnesium sulfate for emergency treatment of arrhythmias
2g over 10-15 minutes
Metformin for T2DM
500 mg OD for 1 week
then 500 mg bd for 1 week
then 500 mg tds
max 2g per day
Metformin for PCOS
500 mg OD for 1 week
then 500 mg BD for 1 week
then 1.5-1.7g in 2-3 divided doses
Metoclopramide for nausea and vomiting
up to 500 mcg/kg daily in s divided doses
weight > 60kg 10 mg up to tds
Metoclopramide for acute migraine
IV/IM 10 mg for 1 dose
Metoprolol for hypertension
immediate release: 100 mg OD then 200 mg in divided doses max 400 mg
MR 200 mg OD
Metoprolol for angina
Immediate release 50-100 mg 2-3x
MR 200-400 mg
Metoprolol for arrhythmias
immediate release 50 mg 2-3 times up to 300 mg in divided doses
IV 5 mg at 1-2 mg/minute then 5 mg after 5 minutes
Metoprolol for migraine prophylaxis
Immediate release 100-200 mg in divided doses
MR 200 mg
Metoprolol for hyperthyroidism
Immediate release 50 mg qds
Metronidazole for Anaerobic infection
400 mg Q8h 7/7
IV 500 mg Q8h 7/7 over 20 minutes
Metronidazole for surgical prophylaxis
400-500 mg 2 hours before surgery then 400-500 mg Q8h for 3 doses
IV 500 mg 30 minutes before the procedure,
IV 500 mg Q8h for 3 doses
Misoprostol for termination of pregnancy following mifepristone
400 mcg to 800 mcg
Morphine for Acute pain
10 mg Q4h
elderly 5mg Q4h
slow infusion 5 mg Q4h
Morphine for chronic pain
5-10 mg Q4h
Morphine for MI
5-10 mg then 5-10 mg if needed at 1-2mg/min
elderly 2.5-5 mg followed by 2.5-5mg if needed at 1-2 mg/min
Morphine for acute pulmonary edema
5-10 mg at 2 mg/minute
elderly 2.5-5 mg at 2 mg/min
N-acetylcysteine for paracetamol OD
> 40 kg 150 mg/kg over 1 hour in 200 mL glucose
then 50 mg/kg over 4 hours in 500 mL glucose
then 100 mg/kg over 16 hours in 1L glucose
Naloxone for opiod OD
IV 400 mg the 800 mg for 2 doses at 1 minute intervals
then 2 mg for 1 dose if no response
IM 400 mcg Q2-3 minutes
Nifedipine for Raynaud’s syndrome
5 mg tds then adjust to response to 20 mg tds
Nifedipine for postponement of premature labor
20 mg then 10-20 mg 3-4x
Norethisterone for menorrhagia to arrest bleeding
5 mg tds 10/7
Norethisterone for menorrhagia to prevent bleeding
5 mg bd from day 19 to day 26
Norethisterone for dysmenorrhoea
5 mg tds for 3-4 cycles from day 5-24 of cycle
Norethisterone for contraception
350 mcg OD at the same time continuously (delayed by 3 hours if a missed pill)
Nortriptyline for depressive illness
75-100 mg in divided doses
max 150 mg
elderly 30-50 mg
Nortriptyline or neuropathic pain
10 mg OD nocte
up to 75 mg
omeprazole for H.pylori eradication
20-40 mg bd 7/7
Omeprazole for gastric ulceration
20 mg OD 8 weeks
Omeprazole for duodenal ulceration
20 mg OD for 4 weeks
Omeprazole for prevention of gastric ulcer relapse
20 mg OD
Omeprazole for prevention of relapse of duodenal ulcer
20 mg OD
Omeprazole for NSAID associated ulcer
20 mg OD 4 weeks
Omeprazole for prophylaxis in patients with a history of NSAID associated ulcer
20 mg OD
Omeprazole for GORD
20 mg OD for 4-8 weeks
Omeprazole for severe oesophagitis
40 mg OD for 8 weeks
Omeprazole for acid reflux
10 mg OD
Ondansetron for prevention of postoperative nausea and vomiting
16 mg 1 hour before anesthesia
Ondansetron for treatment of postoperative nausea and vomiting
4 mg 1 dose IM/IV
Oxycodone for severe pain
Immediate release
5 mg
Q4-6h
Max 400 mg/day
Modified release
10 mg
Q12h
max 200 mg/12 h
Slow IV
1-10 mg
Q4h
IV 2 mg/h
SC 5 mg Q4h
Oxytocin for Induction of labor
IV 0.001-0.004 units/minuteincreased at 30 minute intervals until 3-4 contractions every 10 minutes
Oxytocin for prevention for PPH
Slow IV 5 units
IM 10 units
Oxytocin for treatment of PPH
5 units
Paracetamol for pain/pyrexia
0.5-1g Q4-6h max 4g
Paracetamol for acute migraine
1g for 1 dose
Pethidine for acute pain
50-150 mg Q4h
Pethidine for obstetric analgesia
SC/IM 50-100 mg then 50-100 mg Q1-3h max 400 mg per day
Pethidine for postoperative pain
SC/IM 25-100 mg Q2-3 h
elderly 25 mg Q2-3h
Phenytoin for seizures
3-4mg/kg daily or 150-300 mg OD
200-500 mg OD
Phenytoin for status epilepticus
loading dose 20 mg/kg then 100 mg Q6-8 hours
Prednisone for acute exacerbation of COPD
30 mg OD 7-14 days
Prednisone for croup
Children
1-2 mg/kg
Prednisone for asthma
40-50 mg OD 5/7
Prochlorperazine for psychosis/mania
12.5 mg bd 7/7 adjusted at 4-7 day intervals
usual dose 75-100 mg daily
IM 12.5-25 mg 2-3x
Prochlorperazine for anxiety
15-20 mg in divided doses, max 40 mg
Prochlorperazine for severe nausea and vomiting
20 mg then 10 mg after 2 hours
IM 12.5 mg
Prochlorperazine for nausea and vomiting prevention
5-10 mg 2-3x
IM 12.5 mg PRN
Prochlorperazine for labyrinthine disorders
5 mg tds increased to 30 mg in divided doses then reduced to 5-10 mg
Prochlorperazine for acute migraine
10 mg 1 dose
Pyridoxine for B6 deficiency
20-50 mg 1-3x
Pyridoxine for prophylaxis against isoniazid induced neuropathy
10-20 mg
Pyridoxine for treatment of isoniazid induced neuropathy
50 mg tds
Ranitidine for gastric/duodenal ulceration
150 mg bd for 4-8 weeks
300 mg OD 4-8 weeks nocte
Ranitidine for dyspepsia
150 mg BD 6 weeks
300 mg OD 6 weeks nocte
Ranitidine for NSAID induced gastric ulceration
150 mg bd for 8 weeks
300 mg OD 8 weeks nocte
Ranitidine for NSAID induced duodenal ulceration
300 mg bd for 4 weeks
Ranitidine for Prophylaxis against NSAID induced ulcers
300 mg bd
Ranitidine for GORD
150 mg BD for 8 weeks
300 mg OD for 8 weeks nocte
Ranitidine for moderate to severe GORD
600 mg daily in 2-4 divided doses 12 weeks
Risperidone for psychosis
IM 37.5 mg every 2 weeks adjusted in steps of 12 mg at intervals of at least 4 weeks
Risperidone for acute and chronic psychosis
2 mg in 1-2 divided doses for 1 day
then 4 mg in 1-2 divided doses for day 2
usual dose 4-6 mg
elderly initially 500 mcg BD increase in steps of 500 mcg to 1-2 mg bd
Risperidone for mania
2 mg od
increased in steps of 1 mg
usual dose 1-6 mg
elderly 500 mcg
increased in steps of 500 mcg bd to 1-2 mg bd
Salbutamol for Asthma
Immediate release 4 mg 3-4x, elderly 2 mg 3-4x SC/IM 500 mcg Q4h slow IV 250 mcg IV 5 mcg/minute usual dose 3-10 mcg/min inhaled 100-200 mcg up to 4 times nebulised 200 mcg
Salbutamol for severe acute asthma
nebulized 5 mg every 20-30 minutes
Senna for constipation
7.5-15 mg daily
Simvastatin for hypercholesterolemia
10-20 mg OD
Simvastatin for familial hypercholesterolemia
40 mg then adjust at intervals of 4 weeks to 80 mg
Simvastatin for prevention of CVS events
20-40 mg
Sodium valproate for epilepsy
initially 600 mg in 1-2 divided doses
increased in steps of 150-300 mg every 3 days
maintenance 1-2g daily
Sodium valproate for migraine prophylaxis
200 mg bd then
1.2g-1.5g in divided doses if needed
Spironolactone for edema
100-400 mg daily
Spironolactone for congestive heart failure
25-200 mg daily
Spironolactone for moderate to severe heart failure
25 mg OD then adjust to response to 50 mg OD
Spironolactone for resistant hypertension
25 mg OD
Streptokinase for acute MI
1500 000 units within 12 hours of symptom onset over 60 minutes
Streptokinase for DVT
250 000 units over 30 minutes the 100 000 units every 1 hour for 72 hours
Streptokinase for PE
250 000 units over 30 minutes then 100 000 units every 1 hour for 24 hours
Co-trimoxazole for infection
960 mg bd
IV 960 mg Q12 increased to 1.44 g if needed
Cotrimoxazole for a diabetic foot infection
960 mg bd
IV 960 mg Q12h
increased to 1.44g if needed
Cotrimoxazole for Leg ulcer infection
960 mg BD 7/7
IV 960 mg Q12 increased to 1.44g if needed
Cotrimoxazole for hospital-acquired pneumonia
960 mg BD for 5/7
Cotrimoxazole for acute exacerbation of COPD
960 mg BD 5/7
IV 960 mg Q12h
increased to 1.44g if needed
Sumatriptan for acute migraine
50-100 mg then 50-100 mg after at least 2 hours
Sumatriptan for acute cluster headache
SC 6 mg for 1 dose then 6 mg after at least 1 hour
Temazepam for Insomnia
10-20 mg OD or 30-40 mg OD
elderly 10 mg OD or 20 mg OD
Tenofovir for HBV
25 mg OD
Tenofovir disoproxil for HIV
245 mg OD
Thiamine for mild B1 deficiency
25-100 mg
Thiamine for severe B1 deficinecy
200-300 mg in divided doses
Alteplase for acute MI
10 mg within 6-12 hours of sx onset then IV 50 mg over 60 minutes then 10 mg for 4 infusions, over 30 minutes each
Alteplase for PE
10 mg over 1-2 minutes then 90 mg over 2 hours
Alteplase for acute ischamic stroke
900 mcg/kg within 4.5 hours of symptom onset over 60 minutes
Tramadol for moderate to severe pain
IM/IV/SC 50-100 mg Q4-6h
max 400 mg/day
Immediated release PO 100 mg then 50-100 mg Q4-6h Max 400 mg/day
Tramadol for moderate to severe chronic pain
Immediate release 50 mg
Max 400 mg/day
Tranexamic acid for menorrhagia
1g tds for up to 4 days starting when menstruation starts mac 4g per day
Tranexamic acid for epistaxis
1g tds 7/7
Vancomycin for c.difficile infection
125 mg Q6h for 10/7
increased to 500 mg if needed
Vancomycin for a diabetic foot infection
IV 15-20 mg/kg Q8-12h
Vancomycin for cellulitis/erysipelas
IV 15-20 mg/kg Q8-12h
Vancomycin for infection
15-20 mg/kg Q8-12h
Vancomycin for surgical MRSA prophylaxis
1g 1 dose
Vitamin K1 (phytomenadione) for Major bleeding in patients on warfarin
5 mg 1 dose
Warfarin prophylaxis in rheumatic heart disease, AF, prosthetic valve, VTE, TIA
5-10 mg on day 1
maintemce 3-9 mg
same time each day
Zopiclone for insomnia
7.5 mg OD for up to 4 weeks
elderly 3.75 mg OD up to 4 weeks
Daily Fluid requirements
25-30 mL/kg/day
Daily Na, K, Cl requirements
1 mmol/kg/day
Daily glucose requirement
50-100g/day
Resuscitation fluids
500 mL bolus of NaCl or Hartmann’s over less than 15 minutes
reassess, if ongoing hypovolemia further 250-500 mL bolus
Repeat to max 2000 mL
