MBChB List Cautions Flashcards
Acyclovir
Maintain hydration
Adrenaline
Heart disease, Cerebrovascular disease, DM
Alendronate
Upper GI conditions, ulcers or bleeding
Allopurinol
Can precipitate acute gout flare, not for use in acute gout, ensure adequate fluid intake
Amiodarone
Hypokalaemia,
bradycardia,
Pulmonary function tests, LFTs, TFTs,
Augmentin
Allergy, leukemias, glandular fevers
Aspirin
Under 16 yo, peptic ulcer, heamophilia
Atenolol
Asthma, hypotension, cardiogenic shock, uncontrolled HF, prinzmentals angina, AV block, PVD, DM (mask hypoglycemia)
Atropine
Angle-closure glaucoma, Myasthenia gravis, ileus, pyloric stenosis, megacolon
Beclamethasone
May contain lactulose, infections, LRTI, TB
Bendroflumethiazide
Addison’s, hypercalcaemia, hyponatraemia, Diabetes, gout, SLE, hypokalaemia, SLE
Benzatropine
Myasthenia gravis, paralytic ileus, Pyloric stenosis, toxic megacolon, psychosis, elderly
Bezafibrate
Hypothyroidism,
Hypoalbuminaemia,
gall bladder disease,
nephrotic syndrome
Budesonide
Lactulose, infections, LRTI, TB, DM
Benzylpenicilllin
allergy
Carbamazepine
Cardiac disease
Carbimazole
Agranulocytosis and neutropenia, Blood disorders, may worsen intrathoracic goitre
Cefazolin
Betalactam antibiotic
Cetrizine
epilepsy
Colecalciferol
Hypercalcemia
Codeine
Acute abdomen, arrhythmias, gall stones, Contraindicated in increased ICP, head injury, coma, impaired respiratory function
Chloramphenicol
Avoid prolonged or repeated topical use
Ciprofloxacin
prolongued QT, diabetes
Clopidogrel
Bleeding risk, discontinue 7 days before elective surgery
Colchicine
Cardiac disease, GI disease
Cyclizine
Epilepsy
Dabigatran
bacterial endocarditis, bleeding disorders, GORD
Diazepam
paradoxical hostility/aggression, avoid prolonged use,
Diclofenac
GI bleeding, impaired renal function, dehydration
Digoxin
Hypercalcaemia, hypokalaemia, hypomagnesemia, hypoxia, recent MI
Diltiazem
Bradycardia, AV block, prolonged PR, impaired LV function
Docusate sodium
Avoid in intestinal obstruction
Domperidone
Risk of ventricular arrhythmias, gastrointestinal disorders
Doxycycline
Tooth staining/hypoplasia in children
Formoterol
Hypokalaemia,
Ergometrine
not for use in eclampsia, first/second stage of labor, caution in hypertension, cardiac disease, multiple pregnancies
Erythromycin
electrolyte distrubance, QT elongation
Ethinylestradiol with levonorgestrel
BRCA1 BRCA2, gallbladder disease, VTE risk
Felodipine
Cardiac outflow obstruction, aortic stenosis
Fluconazole
QT prolongation
Flumazenil
use in benzodiazepine dependence can lead to withdrawal
Fluoxetine
Cardiac disease, epilepsy, ECT, DM, bleeding
Fluticasone
chorioretinopathy
Folic Acid
Should not be given alone in pernicious anemia
Furosemide
Anuria, renal failure, hypokalaemia, hyponatremia, can exacerbate DM, can exacerbate gout,
Gabapentin
Diabetes, history of psychosis
Gentamicin
Auditory disorder, Myasthenia Gravis
Glipizide
encourages weight gain
GTN
Not to use in outflow obstruction (e.g. AS), hypotension
Haloperidol
blood dyscrasias,
diabetes,
Parkinsons,
bradycardia
Enoxaparin
hypertension, low body weight
UF heparin
Elderly, hypertension
Topical hydrocortisone
avoid prolonged use
Systemic hydrocortisone
caution in congestive heart failure, DM,
Hydroxocobalamin
Should not be given before diagnosis is established
Ibuprofen
GI bleeding or ulcer, cardiac impairment
Ipratropium
bladder outflow obstruction
Isosorbide dinitrate
Heart failure due to obstruction
Lactulose
intestinal obstruction/perforation, lactose intolerance
Lorazepam
Risk of paradoxical effects,
Losartan
Outflow obstruction, heart failure
Metformin
Lactic acidosis
Metoclopramide
asthma, Parkinson’s, conduction disease
Metoprolol
Diabetes, AV block, COPD, risk of heart block with CCB
Misoprostol
CVD
Morpine
arrhythmias, pancreatitis
N-acetylcysteine
Asthma
Naloxone
CVD, pain, dependence
Nifedipine
aortic stenosis, angina, heart failure, DM
Norethisterone
cardiac dysfunction, DM, breast cancer history
Nortriptyline
arrhythmias, CVD, bipolar, psychosis
Omeprazole
increased fracture risk, risk of GI infections
Ondansetron
Long QT syndrome
Oxycodone
pancreatitis, toxic psychosis
Oxytocin
Restrict fluid intake (risk of hyponatremia), hx of LSCS
Paracetamol
hepatotoxicity, low body weight
Pethidine
neurotoxicity, arrhythmias,
Prochlorperazine
hypotension
Ranitidine
May mask symptoms of gastric cancer
Risperidone
dehydration, Lewy body dementia
Salbutamol
hypokalemiaia
Simvastatin
liver disease, hypothyroidism
Sodium valproate
SLE, liver toxicity
Streptokinase
cavernous pulmonary disease, recent streptococcal disease
Co-trimoxazole
Asthma
Sumatriptan
CAD, hypertension
Temazepam
hypoalbuminaemia, muscle weakness, paradoxical effects
Tenofovir alafenamide
decompensated liver failure, HIV coinfection
Alteplase
AF, bleeding risk
Tramadol
Excessive bronchial secretions, epilepsy, impaired consciousness
Tranexamic Acid
irregular menstrual bleeding, hematuria, oral contraceptive
Vitamin K1
slow injection as risk of vascular collapse
Warfarin
Bacterial endocarditis, bleeding risk
Zopiclone
Chronic pulmonary insufficiency, OSA