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Pharmacology > MBChB List Cautions > Flashcards

MBChB List Cautions Flashcards

1
Q

Acyclovir

A

Maintain hydration

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2
Q

Adrenaline

A

Heart disease, Cerebrovascular disease, DM

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3
Q

Alendronate

A

Upper GI conditions, ulcers or bleeding

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4
Q

Allopurinol

A

Can precipitate acute gout flare, not for use in acute gout, ensure adequate fluid intake

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5
Q

Amiodarone

A

Hypokalaemia,
bradycardia,
Pulmonary function tests, LFTs, TFTs,

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6
Q

Augmentin

A

Allergy, leukemias, glandular fevers

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7
Q

Aspirin

A

Under 16 yo, peptic ulcer, heamophilia

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8
Q

Atenolol

A

Asthma, hypotension, cardiogenic shock, uncontrolled HF, prinzmentals angina, AV block, PVD, DM (mask hypoglycemia)

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9
Q

Atropine

A

Angle-closure glaucoma, Myasthenia gravis, ileus, pyloric stenosis, megacolon

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10
Q

Beclamethasone

A

May contain lactulose, infections, LRTI, TB

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11
Q

Bendroflumethiazide

A

Addison’s, hypercalcaemia, hyponatraemia, Diabetes, gout, SLE, hypokalaemia, SLE

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12
Q

Benzatropine

A

Myasthenia gravis, paralytic ileus, Pyloric stenosis, toxic megacolon, psychosis, elderly

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13
Q

Bezafibrate

A

Hypothyroidism,
Hypoalbuminaemia,
gall bladder disease,
nephrotic syndrome

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14
Q

Budesonide

A

Lactulose, infections, LRTI, TB, DM

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15
Q

Benzylpenicilllin

A

allergy

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16
Q

Carbamazepine

A

Cardiac disease

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17
Q

Carbimazole

A

Agranulocytosis and neutropenia, Blood disorders, may worsen intrathoracic goitre

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18
Q

Cefazolin

A

Betalactam antibiotic

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19
Q

Cetrizine

A

epilepsy

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20
Q

Colecalciferol

A

Hypercalcemia

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21
Q

Codeine

A

Acute abdomen, arrhythmias, gall stones, Contraindicated in increased ICP, head injury, coma, impaired respiratory function

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22
Q

Chloramphenicol

A

Avoid prolonged or repeated topical use

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23
Q

Ciprofloxacin

A

prolongued QT, diabetes

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24
Q

Clopidogrel

A

Bleeding risk, discontinue 7 days before elective surgery

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25
Q

Colchicine

A

Cardiac disease, GI disease

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26
Q

Cyclizine

A

Epilepsy

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27
Q

Dabigatran

A

bacterial endocarditis, bleeding disorders, GORD

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28
Q

Diazepam

A

paradoxical hostility/aggression, avoid prolonged use,

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29
Q

Diclofenac

A

GI bleeding, impaired renal function, dehydration

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30
Q

Digoxin

A

Hypercalcaemia, hypokalaemia, hypomagnesemia, hypoxia, recent MI

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31
Q

Diltiazem

A

Bradycardia, AV block, prolonged PR, impaired LV function

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32
Q

Docusate sodium

A

Avoid in intestinal obstruction

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33
Q

Domperidone

A

Risk of ventricular arrhythmias, gastrointestinal disorders

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34
Q

Doxycycline

A

Tooth staining/hypoplasia in children

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35
Q

Formoterol

A

Hypokalaemia,

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36
Q

Ergometrine

A

not for use in eclampsia, first/second stage of labor, caution in hypertension, cardiac disease, multiple pregnancies

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37
Q

Erythromycin

A

electrolyte distrubance, QT elongation

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38
Q

Ethinylestradiol with levonorgestrel

A

BRCA1 BRCA2, gallbladder disease, VTE risk

39
Q

Felodipine

A

Cardiac outflow obstruction, aortic stenosis

40
Q

Fluconazole

A

QT prolongation

41
Q

Flumazenil

A

use in benzodiazepine dependence can lead to withdrawal

42
Q

Fluoxetine

A

Cardiac disease, epilepsy, ECT, DM, bleeding

43
Q

Fluticasone

A

chorioretinopathy

44
Q

Folic Acid

A

Should not be given alone in pernicious anemia

45
Q

Furosemide

A

Anuria, renal failure, hypokalaemia, hyponatremia, can exacerbate DM, can exacerbate gout,

46
Q

Gabapentin

A

Diabetes, history of psychosis

47
Q

Gentamicin

A

Auditory disorder, Myasthenia Gravis

48
Q

Glipizide

A

encourages weight gain

49
Q

GTN

A

Not to use in outflow obstruction (e.g. AS), hypotension

50
Q

Haloperidol

A

blood dyscrasias,
diabetes,
Parkinsons,
bradycardia

51
Q

Enoxaparin

A

hypertension, low body weight

52
Q

UF heparin

A

Elderly, hypertension

53
Q

Topical hydrocortisone

A

avoid prolonged use

54
Q

Systemic hydrocortisone

A

caution in congestive heart failure, DM,

55
Q

Hydroxocobalamin

A

Should not be given before diagnosis is established

56
Q

Ibuprofen

A

GI bleeding or ulcer, cardiac impairment

57
Q

Ipratropium

A

bladder outflow obstruction

58
Q

Isosorbide dinitrate

A

Heart failure due to obstruction

59
Q

Lactulose

A

intestinal obstruction/perforation, lactose intolerance

60
Q

Lorazepam

A

Risk of paradoxical effects,

61
Q

Losartan

A

Outflow obstruction, heart failure

62
Q

Metformin

A

Lactic acidosis

63
Q

Metoclopramide

A

asthma, Parkinson’s, conduction disease

64
Q

Metoprolol

A

Diabetes, AV block, COPD, risk of heart block with CCB

65
Q

Misoprostol

A

CVD

66
Q

Morpine

A

arrhythmias, pancreatitis

67
Q

N-acetylcysteine

A

Asthma

68
Q

Naloxone

A

CVD, pain, dependence

69
Q

Nifedipine

A

aortic stenosis, angina, heart failure, DM

70
Q

Norethisterone

A

cardiac dysfunction, DM, breast cancer history

71
Q

Nortriptyline

A

arrhythmias, CVD, bipolar, psychosis

72
Q

Omeprazole

A

increased fracture risk, risk of GI infections

73
Q

Ondansetron

A

Long QT syndrome

74
Q

Oxycodone

A

pancreatitis, toxic psychosis

75
Q

Oxytocin

A

Restrict fluid intake (risk of hyponatremia), hx of LSCS

76
Q

Paracetamol

A

hepatotoxicity, low body weight

77
Q

Pethidine

A

neurotoxicity, arrhythmias,

78
Q

Prochlorperazine

A

hypotension

79
Q

Ranitidine

A

May mask symptoms of gastric cancer

80
Q

Risperidone

A

dehydration, Lewy body dementia

81
Q

Salbutamol

A

hypokalemiaia

82
Q

Simvastatin

A

liver disease, hypothyroidism

83
Q

Sodium valproate

A

SLE, liver toxicity

84
Q

Streptokinase

A

cavernous pulmonary disease, recent streptococcal disease

85
Q

Co-trimoxazole

A

Asthma

86
Q

Sumatriptan

A

CAD, hypertension

87
Q

Temazepam

A

hypoalbuminaemia, muscle weakness, paradoxical effects

88
Q

Tenofovir alafenamide

A

decompensated liver failure, HIV coinfection

89
Q

Alteplase

A

AF, bleeding risk

90
Q

Tramadol

A

Excessive bronchial secretions, epilepsy, impaired consciousness

91
Q

Tranexamic Acid

A

irregular menstrual bleeding, hematuria, oral contraceptive

92
Q

Vitamin K1

A

slow injection as risk of vascular collapse

93
Q

Warfarin

A

Bacterial endocarditis, bleeding risk

94
Q

Zopiclone

A

Chronic pulmonary insufficiency, OSA

Pharmacology (17 decks)

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