March 13 test 2

Question 1

What drug can be used to treat both parkinson dz and depression?

Answer 1

Amitriptyline–a TCA

Question 2

What are the symptoms of organophosphate poisoning?

Answer 2

D-Diarrhea
U-Urination
M-Miosis
B-Bronchospasm
B-Bradycardia
E-Excitation of skeletal muscle and CNS
L-Lacrimation
S-Sweating
S-Salivation

Question 3

What NSAID is prescribe to pt with hx of GI ulcers who has RA?

Answer 3

Celecoxib –selective COX-2 inhibitor

Question 4

What is the mechanism of action of the drug that is co-administered with aspirin after stent placement?

Answer 4

ADP receptor inhibitor–inhibit platelet aggregation

-Clopidogrel, prasugrel, ticagrelor, ticlopidine

Question 5

What ADP receptor inhibitor has the side effect of neutropenia?

Answer 5

Ticlopidine

Question 6

What drug can be used to tx both BPH and HTN?

Answer 6

a1-antagonists–relax smooth muscle

• Terazosin
• Tamsulosin
• Doxazosin

Question 7

Co-administration of digoxin with what other drugs can increase the incidence and severity of digoxin toxicity?

Answer 7

Loop diuretics–furosemide, torsemide, ethacrynic acid–which cause hypokalemia and hypo magnesia–allowing for better inhibition of Na/K ATPase by digoxin –yellow vision changes–xanthopsia

Question 8

What psychiatric drug class has anti-cholinergic side effects that cause tachycardia, dry mouth, visual disturbances, urinary retention, constipation?

Answer 8

Traicyclic antidepressants–Clomipramine and amitriptyline

Question 9

What drug is contraindicated with CHF because of its strong negative inotropic effects?

Answer 9

Verapamil–CCB

Question 10

What 2 drugs are used to tx EPS and what class of drugs are do they fall in?

Answer 10

Benztropine and trihexyphenidyl–antimuscarinic–therefore they have DUMBBELLS side effects

Question 11

What cardiac drug is associated with yellow color vision change when it reaches toxic levels?

Answer 11

Digoxin

Question 12

What is the DOC for status epilepticus?

Answer 12

Benzos–Diazepam/lorazepam/midazolam

Question 13

What happens if the action of aldosterone is blocked?

Answer 13

K+ and H+ excretion will be stopped leading to increased K+ and H+ in serum and decreased amounts in the urine

Question 14

What are the complications seen with succinylcholine administration?

Answer 14

Hypercalcemia
Hyperkalemia
Malignant hyperthermia

Question 15

How do you calculate the dosing rate of a drug?

Answer 15

Css x CL

Steady state concentration x Clearance

Question 16

What drug is used to maintain a PDA?

Answer 16

Alprostadil–PGE1 analog

Question 17

What drug is used for the treatment of Amyotrophic lateral sclerosis?

Answer 17

Riluzole–inhibits glutamatergic neruotransmission