Marcadores Tumorales Flashcards

1
Q

Prostata

A
  • PSA libre o PSAL
  • Ratio PSA libre / PSA total (PSAT)
  • Fosfatasa ácida

El PSAL se realiza cuando el PSAT está entre 4-10ng/mL. Ratio de PSAL/PAST -20% indica mala prognosis.

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2
Q

Tiroides

A
  • Tiroglobulina - folicular y papilar-
  • Calcitonina - medular-
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3
Q

Gastrointestinal

A
  • CEA
  • Ca125
  • Ca19. 9

Ca72. 4,Ca50

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4
Q

Pulmón

A
  • CEA - Células no pequeñas
  • Ca125 - Adenocarcima
  • SCC - epidermoide
  • CYFRA 21.1 - epidermoide y no pequeñas
  • Enolasa (NSE) - Células pequeñas
  • TPA (AG polipeptido tisular): para el seguimiento.
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5
Q

Cabeza y cuello

A
  • SCC
  • TPA
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6
Q

Piel

A
  • SCC - Epidermoide
  • Proteína S-100 - melanoma
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7
Q

Vejiga

A
  • BTA
  • CEA
  • TPA
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8
Q

Mama

A
  • Ca15. 3
  • CEA
  • HER-2/NEU
  • receptores de estrógeno y progesterona
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9
Q

Endometrio

A
  • CEA
  • Ca125
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10
Q

Cáncer de cervix

A
  • CEA
  • Cyfra21.1
  • SCC
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11
Q

Hígado

A
  • AFP
  • CEA
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12
Q

Ovario

A
  • CEA
  • Ca125
  • AFP
  • HE4
  • Beta-hCG (tumores germinales)

Ca19.9, Ca72.4

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13
Q

Testículo

A
  • AFP
  • Beta-hCG
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14
Q

Mieloma multiple

A

-Proteína de Bence-Jones (fracción ligera de inmunoglobulina)
- Ig
- Microglobulinas

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15
Q

Pancreas

A
  • Ca19.9
  • CEA
  • Ca50 En caso de ser grupo Lewis negativo
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16
Q

Enfermedad trofoblástica

A
  • Beta-hCG
17
Q

Colorectal

A
  • CEA (marcador de recidiva)
  • Ca19.9
18
Q

Espondilitis anquilosante

A
  • HLA B27
19
Q

Estreptococo A beta-hemolítico

A
  • ASLO o AELO (Antriestreptolisina O)
20
Q

Neuroblastoma

A
  • NSE (Enolasa neuronal específica)
  • Dopamina

& El NSE puede dar falsos positivos en sueros hemolizados por la riqueza de los hematíes en NSE

21
Q

Síndrome de Zollinger-Ellison o Gastrinoma

A
  • Gastrina