Mapping Eukaryote Chromosomes by Recombination Flashcards

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1
Q

Inference:

A

Alleles that are linked on a chromosome tend to be inherited together

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2
Q

Cis or trans confromation?

AB/ab

++/ab

A

Cis

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3
Q

Cis or trans conformation?

Ab/aB

+b/a+

A

Trans

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4
Q

___ causes greater % of parental genotype vs recombinant

A

Linkage

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5
Q

Recombinants are generated by ___ ___

A

Meitoic Crossover

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6
Q

What are the sites of the crossovers?

A

Chiasmata

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7
Q

Crossing over is a ___ and ___ process

A

Breaking and rejoining

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8
Q

Segregation of traits was precisely ___ with crossing over at the chromosomal level

Location is very important because of where ___ occurs

A

Correlated

Segregation

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9
Q

When does crossing over occur in Meiosis

A

4 chromatid stage

4 distinct gametes

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10
Q

Crossing over can occur at the same site in different meiosis but involve ___ chromatids

A

Distinct

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11
Q

In most eukaryotes, crossing over is necessary to successfully ___ meiosis

A

exit

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12
Q

Recombinants arise when crossover occurs between ___ ___

A

nonsister chromatids

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13
Q

When genes are on the same chromosome they are called ___

A

Linked

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14
Q

What units are used to measure genetic distances?

A

most common: centimorgan (cM)

or map units (m.u.)

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15
Q

Genes that are close together on a chromosome have more or less of a chance for recombination?

A

Closer - less/lower chance

Farther - more/higher chance

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16
Q

Physical vs linkage map are ___ correlated but ___ the same

A

Roughly correlated but not the same

17
Q

What results from a two-point or two factor cross?

What results from a three-point or three factor cross?

A

Recombinant

Double recombinant

18
Q

Interference:

A

A crossover in one region of a chromosome reduces the probability of another crossover in that same region.

19
Q

Are centromeres genes?

What do centromeres serve as?

A

No, they serve as spindle attachment points during cell division