Managing Infections

Question 1

How does a superinfection occur

Answer 1

It is a secondary infection which occurs when treating a primary infection

It happens when natural microbiota is distributed and opportunity pathogen stoves

Question 2

Antimicrobial agents can be bacteriostatic, what is this and give examples

Answer 2

Inhibiting or suppressing growth of bacteria, examples of these agents include:
• chloramphenicol
• erythromycin
• tetracycline

Question 3

Antimicrobial agents can be bactericidal, what is this and give examples

Answer 3

Killing of pathogen, examples of these agents include:
• b-lactams
• aminogylcosides

Question 4

Should narrow or widest spectrum be used when treating a infection

Answer 4

Narrowest

Empirical - wide spectrum

Question 5

Give examples of cell wall synthesis inhibitors

Answer 5

• penicillin
• cephalosporin
• cabapentams
• monobactams
^beta lactam
• vancomycin

Question 6

Moa of penicillin

Answer 6

Bind to PBP, inhibiting transpeptide-catalysed reaction, which hinders with the cross links, which are needed for the bacterial cell wall integrity

Question 7

Cell wall synthesis inhibitors?

Answer 7

• penicillin
• celphasporins
• carbapentams
• vancomycin
• monobactams

(B-lactams)

Question 8

Protein synthesis inhibitors?

Answer 8

• chloramphenicol
• macrolides
• tetracyclines
• clindamycin
• aminogylcosides

Question 9

Folate inhibitors

Answer 9

• trimethorpim
• sulphonamides

Question 10

DNA synthesis inhibitors

Answer 10

Quinolones

Question 11

Cell membrane inhibitors

Answer 11

• polymyxin