Influzena

Question 1

What virus is this caused by?

Answer 1

Influzena virus (type A is more common)

Question 2

Which time of year does it occur

Answer 2

December - March

Question 3

Differential diagnosis?

Answer 3

• common cold
• pneumonia
• meningitis
• para influzena

Question 4

Respiratory related complications

Answer 4

• exacerbations of COPD or asthma
• bronchitis
• pneumonia
• otitis media

Question 5

Non respiratory related

Answer 5

• exacerbation of cardiac diseases
• myocarditis
• neurological
• muscle pain

Pregnant women are at higher risk of morbidity and mortality

Question 6

Who at the “at risk groups” who may require ART

Answer 6

• 65>
• <6 months
• pregnant
• heart disease
• liver disease
• imunosupression
• diabetes
• obese

Question 7

ART for high risk patients, all criteria must be met:

Answer 7

• National surveillance indicate that influenza if circulating
• must be of those from high risk group
• must initiate treatment within 48 hours of symptom onset
• >48 hours this is a off label use (use clinical judgment)

Question 8

Symptoms of influenza

Answer 8

• chills
• fever
• headache
• muscle pain
• nasal congestion

Question 9

What are the 2 options of ART?

Answer 9

Oseltamivir

Or

Zanamivir

Question 10

Moa is the same for both

Answer 10

Viral neuraminidase inhibitor

(In influenza A and B)

Question 11

If is a low risk resistance to oseltamivir, what would you give?

Answer 11

Oral oseltamivir

Question 12

If there is a high risk resistance to oseltamivir, what would you give

Answer 12

Inhaled zanamvir

Question 13

Treatment length

Answer 13

5 days

Question 14

Which drug to give for high risk groups

Answer 14

Oseltamivir