Male Repro Flashcards
What is the function of the male testes?
- production of spermatozoa (male gametes)
- production of male sex hormone (testosterone)
What is the function of the ducts?
- sperm storage
- maturation
- transportation
What is the function of the accessory glands of the repro system?
- secrete majority of seminal fluid (semen)
- secretions = maintenance + maturation of sperm
What is the function of the penis?
- male organ of copulation (sex)
- pathway for urine + semen
Name the path semen from production to ejaculation.
Testis > epididymis > ductus deferens > seminal vesicle > prostate gland > ejaculatory duct [+ bulbourethral gland] > urethra
What keeps the testis anchored to the floor of the scrotal sac?
Scrotal ligament
The cremaster muscle covers the spermatic cord down into the testis. It is an extension of which muscle?
Internal oblique muscle from the abdominal wall - “dragged down” when testis “dropped”.
Why does the testis sit away from the body?
Sperm needs to be at least 2 degrees cooler than the body temp - will otherwise die.
What does semen consist of?
- spermatozoa
- secretions of accessory glands
What are the two layers covering the testis?
1) tunica albuginea
2) tunica vaginalis (visceral+parietal layer)
What is the pathway of spermatozoa production within the testis?
1) seminiferous tubules
2) rete testis
3) efferent tubules
- -> epididymis
What are the 2 types of cells found within the seminiferous tubule?
1) spermatogenic cells (meiosis occurs - 1:4)
2) interstitial cells of Leydig (produce testosterone in presence of LH)
Define spermatogenesis.
The process by which sperm is produced within seminiferous tubules (meiosis 1:4)
Name the development process of germ cells to spermatozoa.
Spermatogonia (germ cells) > spermatocye (1, 2) > spermatid > [maturation] > spermatozoa
What are the 2 functions of sertoli (nurse) cells?
1) creates blood-testis barrier (create extremely tight junctions to separate maturing cell system from vasculature - attack of immune system on maturing cells)
2) nurtures process of spermatogenesis (FSH)
What is spermiogenesis?
- final stage of spermatogenesis
- transformation of round spermatid into asymmetrical spermatozoon
Describe the transformation of a round spermatid into an asymmetrical spermatozoon.
- condensation of nucleus
- formation of acrosome (enzymatic pouch)
- flagellum development
What generates the beating of the flagellum of the spermatozoon?
MITOCHONDRIAL SPIRAL in midpiece - produces ATP to generate beating
What is the importance of a spermatozoon’s acrosome?
- contains enzymes to bore a hole in egg’s zona pellucida
- breaks down in contact w/ egg to allow sperm to reach egg’s plasma membrane = + Ca+ [fuse] = fertilization
Why does the immune system see sperm proteins as foreign?
Only spermatogonia + Sertoli cells present @ birth.
Foreign = spermatocyes, spermatids, sperm
What is the role of interstitial cells [of Leydig]?
- found within seminiferous tubule
- produce TESTOSTERONE in presence of LH
What role does testosterone play?
- regulates spermatogenesis
- stimulates development + maintenance of male secondary sex characteristics
What is the role of FSH?
FSH stimulates Sertoli cells [in seminiferous tubules] to support spermatogenesis
What is the role of LH?
LH stimulates Leydig [interstitial cells] in seminiferous tubules to produce testosterone