Male/Female Embryo Flashcards

1
Q

Mesonephric duct degenerates; Paramesonephric duct develops

A

Female

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2
Q

Produces testis-determining factor

A

SRY gene on Y chromosome

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3
Q

Secrete Mullerian inhibitory factor that suppresses the development of the paramesonephric ducts

A

Sertoli Cells

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4
Q

Secrete androgens that stimulate the development of the mesonephric ducts

A

Leydig cells

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5
Q

Develops into fallopian tubes, uterus, and upper part of vagina

A

Paramesonephric (Mullerian) Duct

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6
Q

Lower vagina

A

Urogenital sinus

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7
Q

Develops into seminal vesicles, epididymis, ejactulatory duct, and ductus deferens

A

Mesonephric (Wolffian) Duct

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8
Q

Results from incomplete fusion of the paramesonephric ducts

A

Bicornuate uterus

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9
Q

SRY gene without sertoli cells or lack MIF

A

both male and female internal genitalia and male external genitalia

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10
Q

5alpha reductase deficiency

A

inability to convert testosterone into DHT; male internal genitalia, ambiguous external genitalia until puberty (testosterone increases causing masculinization)

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11
Q

Genital Tubercle with DHT

A

Glans penis; Corpus cavernosum and spongiosum

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12
Q

Genital Tubercle with Estrogen

A

Glans clitoris; vestibular bulbs

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13
Q

Urogenital sinus with DHT

A

Bulbourethral (Cowper) Glands and Prostate

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14
Q

Urogenital sinus with Estrogen

A

Greater vestibular glands (Bartholin); Urethral and paraurethral glands of Skene

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15
Q

urogenital folds with DHT

A

Ventral shaft of penis (penile urethra)

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16
Q

Urogenital folds with Estrogen

A

Labia Minora

17
Q

Labioscrotal swelling with DHT

A

Scrotum

18
Q

Labioscrotal swelling with Estrogen

A

Labia Majora

19
Q

Abnormal opening of penile urethra on inferior (ventral) side of penis due to failure of urethral folds to close

A

Hypospadias

20
Q

Abnormal opening of penile urethra on superior (dorsal) side of penis due to fault positioning of genital tubercle

A

Epispadias

21
Q

Ovarian ligament + round ligament of uterus

A

Gubernaculum (band of fibrous tissue)

22
Q

Anchors testes within scrotum

A

Gubernaculum (band of fibrous tissue)

23
Q

Forms tunica vaginalis

A

Processes vaginalis (evagination of peritoneum) - obliterated in women

24
Q

Adenosis

A

focal persistence of columnar epithelium in upper vagina due to increased incidence of women exposed to DES in utero

25
Q

DES

A

prevents columnar to squamous development of vagina if fetus is exposed to it in utero