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First Aid Reproductive > Breast Pathology > Flashcards

Breast Pathology Flashcards

1
Q

Nipple diseases

A

Paget; Abscess

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2
Q

Lactiferous Sinus Diseases

A

Intraductal papilloma; abscess and mastitis

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3
Q

Major Duct Diseases

A

Fibrocystic change; DCIS; invasive ductal carcinoma

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4
Q

Terminal Duct Diseases

A

Tubular carcinoma

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5
Q

Lobule Diseases

A

Lobular Carcinoma

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6
Q

Breat Stroma Diseases

A

Fibroadenoma; phyllodes tumor

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7
Q

Small, mobile firm mass with sharp edges; Not a precursor to breast cancer

A

Fibroadenoma

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8
Q

Small tumor that grows in lactiferous ducts typically beneath areola; serous or bloody nipple discharge

A

Intraductal papilloma

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9
Q

“leaf like projections” most common in 50s

A

Phyllodes Tumor

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10
Q

Large bulky mass of CT and cysts

A

Phyllodes Tumor

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11
Q

Overexpression of c-erbB2 (HER-2)

A

Malignant breast tumor

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12
Q

LN used to indicated breast cancer metastasis

A

Axillary

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13
Q

Triple Negative breast cancer

A

ER (-); PR(-); and Her2/Neu (-)

most aggressive

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14
Q

BRCA1

A

Breast and Ovarian Carcinoma (medullary breast)

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15
Q

BRCA2

A

Breast carcinoma (in men too)

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16
Q

Most common male breast cancer

A

Invasive ductal carcinoma; assoc with BRCA2 and Klinefelter

17
Q

Ductal Carcinoma In Situ (DCIS)

A

Fills ductal lumen; arises from ductal atypia; microcalcifications on mammography

18
Q

Ductal caseous necrosis; dysmorphic calcification in center of ducts

A

Subtype of DCIS known as Comedocarcinoma

19
Q

Ecxematous patches on nipple

A

from underlying DCIS; Pagets of breast (not vulva)

20
Q

Large cells in epidermis with clear halo

A

Paget cells

21
Q

malignant epithelium of vulva; erythematous, pruritic, ulcerated skin

A

Extramammary Paget

22
Q

Firm, fibrous, “rock-hard” mass with sharp margins and small, glandular, duct-like cells

A

Invasive ductal breast cancer

23
Q

Stellate infiltration

A

Invasive ductal breast cancer; worst and most invasive type

24
Q

Orderly rows of cells “Indian File”

A

Invasive lobular breast cancer

25
Q

Fleshy, cellular, lymphocytic (plasma) infiltrate

A

Medullary breast cancer; good prognosis

26
Q

Dermal lymphatic invasion by breast carcinoma; Peau d’orange

A

Inflammatory breast cancer (neoplastic cells block lymphatic drainage

27
Q

Most common cause of “breast lumps” from 25 to menopause; presents with premenstrual breast pain and multiple lesions; fluctuates in size

A

Proliferative Breast Disease

28
Q

Types of Proliferative Breast disease

A

Fibrosis; cystic; sclerosing adenosis; epithelial hyperplasia

29
Q

hyperplasia of breast stroma; breast pain with periods

A

Fibrosis type of proliferative breast disease

30
Q

Fluid filled; blue dome; ductal dilation

A

Cystic type of prolfierative breast disease

31
Q

Increased acini and intralobular fibrosis; associated with calcifications

A

Sclerosing adenosis; commonly confused with cancer

32
Q

Increased number of epithelial cell layers in terminal duct lobule; increased risk of carcinoma with atypical cells

A

Epithelial Hyperplasia type os proliferative breast disease

33
Q

Breast abscess during breast feeding

A

Acute mastitis

34
Q

Most common bacteria that causes acute mastitis

A

S. aureus

35
Q

Tx of acute mastitis

A

Dicloxacillin and continued breast feeding

36
Q

Injury to breast tissue; abnormal calcification

A

Fat necrosis

37
Q

Causes of Gynecomastia

A

Hyperestrogenism (cirrhosis, testcular tumor, puberty, old age); Klinefelter, Spironolactone, marijuana, digitalis, estrogen, cimetidine, alcohol, heroin, dopamine D2 antagonist, ketoconazole

First Aid Reproductive (15 decks)

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