Lady Part Problems Flashcards
Disordered epithelial growth at basal layer of squamoucolumnar junction
Dysplasia and carcinoma in situ
koilocytes
Cervical condyloma; wrinkled “raisinoid” nuclei with clearing or perinuclear halo
HPV vaccine
Quadrivalent vaccine that covers HPV 6, 11, 16, 18
Inflammation of endometrium with plasma cells and lymphocytes - usually associated with retained products of conception
Endometritis
Tx of Endometritis
Gentamicin + Clindamycin w/ or w/o ampicillin
Non-neoplastic endometrial glands/stroma outside of the endometrial cavity
Endometriosis
Cyclic pelvic pain, bleeding, dysmenorrhea, dyspareunia, dyschezia (pain with defecation), infertility, normal-sized uterus
Endometriosis
Chocolate cyst
Endometriosis of the ovaries (most common site)
Extension of endometrial tissue into the uterine myometrium caused by hyperplasia of basalis layer
Adenomyosis
Uniformly enlarged, soft, globular uterus; dysmenorrhea, menorrhagia
Adenomyosis
Well-circumscribed collection of endometrial tissue within the uterine wall. May contain smooth muscle and can extend into endometrial cavity
Adenomyoma polyp
Abnormal endometrial gland proliferation usually caused by excess estrogen stimulation; post menopausal vaginal bleeding
Endometrial hyperplasia
Most common gynecologic malignancy that occurs at 55-65y/o
Endometrial carcinoma; typically preceded by endometrial hyperplasia
Most common tumor in females
Leiomyofibroma, benign smooth muscle tumor
Whorled pattern of smooth muscle bundles with well-demarcated borders
Leiomyofibroma
Signs of menopause after puberty before the age of 40; premature atresia od ovarian follicles
Premature ovarian failiure
Have decreased estrogen and increased LH and FSH
Enlarged BL cystic ovaries; presents with amenorrhea/oligomenorrhea, hirsutism, acne, infertility
PCOS or Stein-Leventhal Syndrome
Distention of unruptured graafian follicle; may be associated with hyperestrogenism and endometrial hyperplasia
Follicular cyst
Hemorrhage into persistent corpus luteum; common regresses spontaneously
Corpus luteum cyst
Often BL/multiple; gonadotropin stimulation; associated with choriocarcinoma and moles
Theca-lutein cyst
Blood vessel rupture in cyst wall. Cyst grows with increased blood retention
Hemorrhagic cyst
Mature teratoma. Cystic growths filled with various types of tissue such as fat, hair, teeth, bits of bone and cartilage
Dermoid Cyst
CA-125
way to monitor progression of ovarian neoplasms
Most common malignant ovarian neoplasm; psammoma bodies
cystadenocarcinoma
Multiloculated, large. Lined by mucus-secreting epithelium
Mucinous Cystadenoma
Mass arising from growth of ectopic endometrial tissue. Complex mass on US; pelvic pain, dysmenorrhea, dyspareunia
Endometrioma
Struma ovarii
Mature Teratoma with functional thyroid tissue
Solid tumor that is pale yellow-tan in color and appears encapsulated. “coffee bean” nuclei; looks like bladder
Brenner Tumor
triad of ovarian fibroma, ascites and hydrothorax
Pulling sensation in groin
Meigs Syndrome
Tumor that may produce estrogen, usually present as abnormal uterine bleeding in a postmenopausal woman
Thecoma
Agressive neoplasm with fetal tissue, neuroectoderm
Immature teratoma
Most common sex cord stromal tumor. Call-Exner bodies
Granulosa Cell tumor
Intraperitoneal accumulation of mucinous material from ovarian or appendiceal tumor
Pseudomyxoma peritonei (mucinous cystadenocarcinoma)
Equivalent to male seminoma
Dysgerminoma
Sheet of uniform “fried egg” cell; uses hCG and LDH as tumor markers
Dysgerminoma
Malignant ovarian neoplasm that can develop during or after pregnancy in mother or baby; no chorionic villi; presents with abnormal hCG, SOB, hemoptysis
Choriocarcinoma
Schiller-Duval Bodies (resemble glomeruli)
Yolk sac (endodermal sinus) tumor
GI malignancy that metastasizes to the ovaries
Krukenberg tumor
mucin-secreting signet cell adenocarcinoma
Krukenberg tumor
