Malaria

Question 1

Name the four species of malaria

Answer 1

Vivax
Falciparum
Ovale
Malariae

Question 2

Where does malaria parasite incubate?

Answer 2

in the liver

Question 3

How is a diagnosis made for malaria?

Answer 3

antigen test, followed by thin film to determine which species (PCR is also done)

Question 4

Three clinical features of malaria?

Answer 4

fever, malaise, headache, diarrhoea, anaemia, jaundice, renal impairment

Question 5

Two severe outcomes in malaria?

Answer 5

renal failure, shock, pulmonary oedema, cerebral malaria, severe anaemia, parasitaemia , lactic acidosis, hypoglycaemia, DIC

Question 6

What is the treatment for malaria?

Answer 6

dual therapy- quinine and doxicycline

Question 7

What chemoprophylaxis is available for malaria?

Answer 7

1. Mefloquine- once weekly 2. Doxycicline- daily 3. Malarone

Question 8

One side effect of mefloquine?

Answer 8

psychiatriac SE- vivid dreams

Question 9

SE of doxycycline?

Answer 9

photosensitisation

Question 10

Two signs of falciparum malaria?

Answer 10

anaemia

jaundice

Question 11

Which malaria infection leads to the most serious symptoms?

Answer 11

falciparum

Question 12

Name four investigations for malaria

Answer 12

Blood films
FBC
Clotting
Glucose
ABG
U+Es
Urinalysis

Question 13

Specify three blood tests you would conduct in malaria and provide justification

Answer 13

FBC- anaemia, thrombocytopenia

Clotting- DIC

U+E- renal failure

Glucose- hypoglycaemia

Question 14

Three symptoms of malaria

Answer 14

Flu-like prodrome (headache, myalgia, malaise)

Fever- shivering then sweating