Malabsorption Flashcards
Pale offensive greasy diarrhea suggest:
Fat malabsorption
Abdominal bloating, flatus, diarrhea suggest:
Carb malabsorption
Edema muscle atrophy amenorrhea suggest
protein malabsorption
Fat soluble vitamins:
ADEK
Fat malabsorption increase risk of
oxalate stone formation
Vitamin A is a cofactor in
collagen synthesis
Vitamin D promotes
absorption of calcium and phosphorus
Patient with:
Dermatitis, zeropthalmia, pneumonia, impaired gut epithelial integrity
Vitamin A deficiency
Patient with:
Bone demineralisation, rickets, osteomalacia
Vitamin D deficiency
Which vitamins has antioxidant properties?
Vitamin A, C & E
Patient present with bruising or hemorrhage
Vitamin K deficiency
Ber-beri, lactic acidosis, and fatigue occur with:
Thiamin (B1) def
If patient has thiamine def what do we see on x-ray?
Cardiomegaly
Biotin is B_?
7
Glossitis, dermatitis, pallor, and hair loss is ___ def
Biotin (B7)
Cobalamin (B12) def result in
Megaloblastic anemia/pernicious anemia
degeneration of spinal cord
Vitamin C deficiency
Scurvyy
gingivitis
capillary weakness
Ca def result in
osteoporosis
What happens if copper is high?
Wilson disease
Impaired glucose tolerance, anemia, neutropenia, leukopenia, changes in skin and hair pigmentation
Copper def
cheilosis, glossitis,koilonychias, hair loss
Iron def
Magnesium def result in
Nausea, muscle weakness, irritability, mental derangement
dermatitis
delayed sexual maturation
testicular atrophy
delayed sexual maturation
Zinc def
crodermatitis enteropathica occur in
Zinc def
the commonest nutritional deficiency in Saudi Arabia and worldwide
Iron deficiency anemia
Vitamin D def value
less than 3 μg/day
Vitamin D toxicity value
> 50 μg/day
Adult male has ___total body iron stores
~4g
Iron absorption is inhibited by
tannins
systemic inflammation
Most dietary iron is ___
Nonheme
intracellular storage of iron
Ferritin
long term iron storage pool
Hemosiderin
plasma iron transporter protein. (less than 1%)
Transferrin
Low much iron is lost per day?
<0.05%
Example of Iron def due to Failure to meet increased requirements
Menstruation, pregnancy
Example of Iron def due to Inadequate iron absorption
Excessive cow’s milk intake in infants
Ferritin is ___ in IDA
Low
Ferritin is ___ in inflammation
highh
Marrow iron is __ in IDA and __ in inflammation
low, not changed
How to treat IDA?
oral iron
in IDA, Hb will normalize after
2 months
in IDA, iron will normalize after
5 months
