Chronic Diarrhea- Case conference Flashcards

1
Q

quantify the amount of liquid being screted as gastric juice

A

2.5 L/d

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2
Q

amount of liquid created

A

7 L/d

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3
Q

amount of fluid that enters the GI system

A

9-Aug

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4
Q

the small bowel reabsorbs ____of fluid

A

6-7 L/d

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5
Q

the large bowel reabsorbs ____of fluid

A

1-2 L/d

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6
Q

how much fluid is sereted in stool

A

1%, 100mL/d

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7
Q

list the 4 important types of chronic diarrhea

A

osmotic, secretory/watery, inflammatory, fatty

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8
Q

ions such as magnisum ans sulphate cause ______type of diarrhea. State another substance that causes the same effect

A

osmotic, phosphate

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9
Q

sugars/ alcohol sugars i.e. mannitol,sorbitol lactase deficiency cause __________type of diarrhea

A

osmotic

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10
Q

disordered electrolyte transportation describes this type of diarrhea

A

secretory

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11
Q

after any gastroenteritis theres a transiet lactase deiciency, state the type of diarrhea that follows

A

osmotic

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12
Q

which type of diarrhea stops during fasting

A

osmotic

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13
Q

malabsorption or secretion of electoyles is characteristic of this type of diarrhea

A

secretory

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14
Q

diarrhea thatÕs persistant during fasting

A

secretory

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15
Q

which is more severe, osmotic or secretory diarrhea, state the stool gap both each

A

secretory has larger volume, it has normal stool osmotic gap no inflammation. Osmotic has high stool osmotic gap, positive for leukocytes and is less severe than secretory

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16
Q

state two inflammatory causes of secretory diarrhea

A

microscopic colotis, intestinal ischemia

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17
Q

state different tyoes of infalmatoy diarrhea

A

IBD, ischemic colotis, malignancy

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18
Q

state 4 different infectious causes of inflammatory diarrhea

A

invasive bacterial/ parasitic, pseudomemranous colotis, ulcerating viral infections

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19
Q

state two bacterial causes for inflammatory diarrhea

A

yersinia, TB

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20
Q

state two inflammatory diarrhea causes that are parasitic in origin

A

amebiasis, stronglyoids

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21
Q

pseudomembranous colotis is a cause of

A

c diff

22
Q

the only parasite that can cause chronic diarrhea and may cause fatty diarrhea

A

giardia

23
Q

celiac sprue, and whipple disease are both causes of

A

malabsorption thus fatty diarrhea

24
Q

name two pathologes od increased motility

A

IBS, hyperthyroidism

25
Q

peripheral neruopathy and easy brusiing is suggestive of whicch tpy wof diarrhea?

A

fatty

26
Q

blood, ,mucus, pus and small volume are all signs of

A

inflammatory chronic diarrhea

27
Q

medications must be stiooed for _____to rule out the cause

A

2 weeks

28
Q

3 causes of clubbing related to this block

A

liver cirrhosis, IBS, celiac disease

29
Q

dermatitis herpetiformis is a skin lesion that suggests

A

celiac disease

30
Q

erythema nodsum/ pyoderma gangrenosum are suggestivve of

A

IBD

31
Q

hyperpigmentation is a sign of

A

addisions disease

32
Q

whats pathognomic for celiac disease

A

anti-transglutaminase IgA Ab, anti-endomyseal IgA Ab

33
Q

other than leykocytes whats another marker for infllmation

A

calprotectin

34
Q

fecal occult blood, what is uspected?

A

Crohns disease

35
Q

if fat is suspected, which tet is usally performed

A

sudan

36
Q

musosal atrophy is characterisitic of

A

celiac disease

37
Q

T or F, empiritc course of antibotics is helpful in chronic diarrhea

A

not usefull, false

38
Q

if antibiotics are diven in chronic diarrhea, a complication might be

A

Hemolytic uremic syndrome

39
Q

bile acidting resins are used in pts with

A

liver disease

40
Q

clonidine is used in pts with

A

diabetic diarrhea

41
Q

name a somatostatin analogue used in carcinoid syndrome, dumping syndrome, AIDS diarrhea

A

octreotide

42
Q

whats the best marker for amalbsorption

A

albumin

43
Q

Abnormal small intestine mucosa due to intestinal reaction to _________is known as celiac disease

A

gliadin

44
Q

whats the only autoimmune disease in which androgen alpha gliadine recognized

A

celiac

45
Q

celiac disease is also associated with other diseases like

A

thyroid and DM type 1

46
Q

important markers for celiac disease, which is better?

A

HLA DQ2 HLADQ8, 2 is more important

47
Q

celiac disease is most severe this part of the bowel, and result in defiency 3

A

proximal, Fe,Ca, folic acid

48
Q

if pt isn’t compliant on a gluten free diet, state the prognosis of such a pt

A

lymphoma, carcinoma of the bowl

49
Q

deep ulcers on biopsy may suggest

A

chrons disease

50
Q

state another symptom of this disease , then mention what it is1. foully fatty stoolÓ steatorrhea
2. Acanthocytosis (spiked RBCs)
3. Low cholesterol

A

abetalipoproteinemai, ataxia

51
Q

state 3 definitions for diarrhea

A

_ Increased stool water content / fluidity
_ Increased stool weight: > 200 gm/d
_ 3 or more BMs daily than usual stool habit.

52
Q

how much fluid us ingested

A

1-2 L/d