Epidemic gastroenteritis and travelers diarrhea Flashcards

1
Q

most common cause of acute gastroenteritis in developed and developing countries

A

viruses

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2
Q

most common route for gastroenteritis transmission

A

fecal oral route

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3
Q

whats the most important factors that renders infants more pron to gastroenteritis

A

lack of speicific immunity

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4
Q

toxin production leads to which type of diarrhea

A

secretory

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5
Q

bacterial adherence leads to which type of diarrrhea

A

osmotic

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6
Q

name the bacteria that invades and causes gastroenteritis

A

shigella

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7
Q

state the age of this pathology usually manifests in, blood stool, account for 10-20% of causes of gastrogenteritis

A

> 2 years old

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8
Q

70-90% of gastroenteritis is _________

A

viral bitch

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9
Q

most common cause of acute gastroeneteritis

A

rotaviruus

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10
Q

highest indicence and incubation for rota virus

A

6months to 2 y, incubation:2 days

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11
Q

most commonly isolated bacterial fecal pathogen

A

campylobacter jejuni

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12
Q

curved, common in summer, affects large bowel, mimics appendicitis, state the type of diarrhea and the name of the organism

A

campylobacter jejuni, grossly bloody diarrhea

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13
Q

Toxin similar to cholera
Watery, large volume diarrhea

A

enterotoxigenic E coli

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14
Q

Infects and disrupts enterocytes
Musty smelling stool w/o blood or mucous

A

enteropathogenic E coli

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15
Q

E coli similar to shigella

A

enteroinvasive

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16
Q

Cytoxins result in destruction of enterocytes
Bloody diarrhea
O157:H7 subclass associated with hemolytic uremic syndrome (acute renal failure, microangiopathic hemolytic anemia, thrombocytopenia,
fever)
_

A

enterohemorrhagic E coli

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17
Q

non lactose fermenting motile gram negative rods, osteomylitis

A

salmonella

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18
Q

common in the fall, nonmotile agnr, NON LACTOSE FERMENTING, complicatioons includetoxic megacolon, cholestatic hepatitis, HUS, Reiter syndrome, seizures. State the smell of this stool, which part of the bowel it invades

A

large bowel invasion, fruity or vinegary stool smell

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19
Q

treatment of shigella

A

ceftriaxone

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20
Q

motile gram negative coocobacillius, mimics appendicitis, affcts the small bowel

A

yersinia enterocolitica

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21
Q

uncooked crustaceans, mollusks

A

V cholera

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22
Q

Ingestion of infected cysts resulting in loose, bloody, mucoid diarrhea
Ð May be complicated by hepatic abscess

A

entomeba histolytica

23
Q

contaminated freseh water streams, higher risk for severe disease with IgA deficiey or cystic fibrosis. How is this diagnosid

A

direct inspection of stool or ELISA , giardia lamblia is isolated

24
Q

complication of rotavirus vaccine

A

intussesption

25
enteric fever affects which part of the bowele and mention what is seen on stool examination, and the mechanism
distal small bowel, fecal mononuclear leukocyte, penetration
26
Dysentry affects which part of the bowele and mention what is seen on stool examination, and the mechanism
colon, fecal neutrophil, increase lactoferrin, invasion/cytotoxin
27
watery diarrhea affects which part of the bowele and mention what is seen on stool examination, and the mechanism
proximal small bowel, mild or no increase lactogerrin, no leukocytes, noninflamatory enteortoxin/adherence
28
the following are the most common causes of _________________: (ETEC,EPEC,EAEC) ,Norwalk,Giardia,Staphaur eus,Cl.perfringes. Shigella,E.coli(EIEC ,EHEC) Salmonella enteritidis,Cl.deffic ile,E.histolytica.
dysentery
29
commenest cause of food posioning is
staph aureus
30
food-borne disease outbreak is defined by the following 2 criteria:
1. Similar illness, often GI, in a minimum of 2 people 2. Evidence of food as the source
31
noninflammatory type of food posioning acts without invasion through secretory mechanisms. Example of organisms
Vibrio cholerae, enterotoxic E coli, Clostridium perfringens, Bacillus cereus,Staphylococcus organisms , Giardia lamblia, Cryptosporidium, rotavirus, norovirus and adenovirus.
32
food posioning can either be inflammatory or noninflammatory, which of the preceding is more likely to be associated with dehyrations
noninflammatory
33
examples of inflammatory causes of food positioning
Campylobacter jejuni, Vibrio parahaemolyticus, enterohemorrhagic and enteroinvasive E coli, Yersinia enterocolitica, Clostridium difficile, Entamoeba histolytica, Salmonella and Shigella.
34
Proctitis syndrome (painful bowel movements containing blood, pus, and mucus)
shigellosis
35
vomitting, think of
staph a, NOROVIRUS
36
bloating, think of
giardiasis
37
produse rice-water stool
cholera
38
reactive arthritis, think of
salmonerla, shigella, campylobacter and yersinia
39
undercooked meat
salmonella/ shiga toxin of E coli
40
unpasteurized soft cheese
salmonella, campylobacter
41
homemade canned food
C botulinum
42
raw seafood
Norwalk-like virus , Vibrio or hepatitis A.
43
which type of E coli is treated with cipro
enteroaggressive E coli
44
90% of are asymptomatic, liver abscesses, workup includes, treatment includes
colonscopy w/ biospy. Treatment: paromomycin + metronidazole
45
initial test in Gardia lamblia, where is it in highest concentration
stool enzyme linked immunosorbent assay, highest conc in distal duodenum, proximal jejum
46
treatment of G lamblia
metronidazle
47
when do u do blood culture
pt is notably febrile
48
if patients have fever or symptoms persisting for longer than 3-4 days.
stool culture
49
help to differentiate invasive disease from noninvasive disease.
Gram staining and Loeffler methylene blue staining of the stool for WBCs
50
3 main strains that cause travelers diarrhea
OHK
51
pt going to mexico/ morroco/ thialand, which drug prophylaxis is recommended
azithromycin
52
"Inflammation of the stomach and intestine, of | viral origin"
epidemic gastroenteritis
53
how long within the patients recovery is needed to rule an epidemic gastroenteritis
within 10 days