Gastrointestinal infections Flashcards

1
Q

leading cause of childhood death

A

diarrheal diseases

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2
Q

first thing that comes to mind person - person transmiision ex. Daycare

A

shigella

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3
Q

first thing comes to mind with antibiotics/chemo

A

C diffucile

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4
Q

first think comes to mind with mayo & cream

A

staph

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5
Q

first thing comes to mind with eggs

A

Salmonella

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6
Q

first thing comes to mind with beef

A

shiga-toxin produced by E coli

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7
Q

first thing comes to mind w/ piltry

A

campylobacter

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8
Q

first thing comes to mind with seafood

A

vibrio

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9
Q

first thinf in mind in foodborne outbreak

A

Salmonella

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10
Q

pt developed symp lasting less than 6H, think of

A

preformed toxins of 1. Staph A 2. B cereus

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11
Q

pt developed symp lasting less than 24H, think of

A

preformed toxins 1. B cereus 2. C perfringens

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12
Q

what kind of preformed toxin do u think about if the pt developed symp lasting 72 h

A

think about the live pathogen not the toxins atm

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13
Q

how do u test for toxins

A

stool micriscipy/culutre

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14
Q

what are the pathogens that have an infectious dose of 10^1-2

A

Shigeela, giardia lamblia, entamoeba histolytics

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15
Q

what are pathogens that have an infectious dose of 10^8

A

E coli, vibrio choleria

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16
Q

neurotoxins are produced by the following

A

Staph A, B cereus, C perfringens

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17
Q

Enterotoxins are produced by the following

A

Aeromonas, enterotix E coli, vibrio cholera

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18
Q

cytotoxins are produced by the following

A

C diffcile, e Coli 0157:H7 (hasat a5o 90210)

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19
Q

4 organisms that enteroadherenet

A

cryptosporidiosis, enteroadherent and enteropathogenic E coli, Helminths, Giardiasis

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20
Q

minimal mucosal invasion

A

norwalk virus, rota virus

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21
Q

variable musocal invasion

A

Salmonella, Campylobacter

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22
Q

severe mucosal invasion

A

entamoeba histolytica, enteroinvasive E coile, shigella

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23
Q

which is more severe, salmonella or shigella

A

shigella

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24
Q

watery, pain mid abdominal, state the location of diarrhea

A

small bowel

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25
Q

pain in large bowel diarrhea is

A

left lower quadrant

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26
Q

fecal leukocytes

A

shigellosis, Enteroinvasive E coil, C difficule, Ulceratic/ischemic colitis

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27
Q

persistant diarrhea >2 weekks

A

think parasitic: Giardi lamblia, Cryptospsoridum parvum, if immune compromized think: microsporidium, mycobacterium avium, CMV

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28
Q

fever, headahce, myalgia then abdominal pain + bloody diarrhea, whats the pathogen invovled, and how is it aquired

A

campylobacter jejuni, poultry, contaminated water/food

29
Q

quantify the amount of Guillain-Barre associated with Campylobater, and when does it occur

A

1-3 weeks after diarrhea, 20-40% of GBS

30
Q

Describe the paralysis seen in pts with GBS

A

ascending paralysis; starts at lower extremitis and moves up

31
Q

aquired through eating eggs and exposure to pet reptiles

A

salmonella

32
Q

untreated salmonella lasts

A

4-10 days

33
Q

incubation period for typhoid fever

A

7-14 days

34
Q

severe nonspecific febrile illness, diffuse abdominal pain, tenderness

A

typhoid fever

35
Q

monocytic infilration inflames peyer patchs and narrows the bowel lumen leading to constipation

A

typhoid fever

36
Q

rose sports, salmon colored, blancing, truncal maculopapules, when do these symptoms occur in typhoid fever

A

end of the first week

37
Q

abdomen distended, soft spleomaglay, relative bradycardia, when do these symptoms occur in typhoid fever

A

second weekw

38
Q

pt is anoresix, significant weight loss w/ pulomary and CNS manifestations, when do these symptoms manifest in typhoid fever

A

3rd week

39
Q

pt with biliary tract disease and gallstones, what do you suspect

A

salmonella carrier state

40
Q

when do the symptoms of shigellosis develop

A

12H after ingestion

41
Q

fever, abdominal pain, tenesmus, bloody diarrhea

A

shigellosis

42
Q

which type of shigella is associated with HUS

A

S. dysenteriae

43
Q

why is treatment recommended in shigella

A

prevent secondary spread tp contacts

44
Q

E coli that presents with watery diarrhea/ itÕs the most common cause of travelers diarrhea

A

enterotoxigenic

45
Q

diarrhea in infants in developing countries, state the type of E coli

A

enteropathogenic

46
Q

dysentry with blood + mucus, state the type of E coli

A

enteroinvasive

47
Q

copious bloody diarrhea, HUS in kids, TTP in adults, state the type of Ecoil

A

enterohemorrhagic, 0157:H7

48
Q

whats the most common strain of E coli in developed countires

A

enterohemorrhagic, 0157:H7

49
Q

associated with petting zoo, transmitted by beed

A

enterohemorrhagic, 0157:H7

50
Q

infectious dose of 0157:H7

A

100 bacteria bitch

51
Q

name the toxin that 0157:H7 releases

A

shiga toxin

52
Q

related to antibiotic clindamycin, toxins A and B, nosocomial transmission, state the pathology associated with this disease

A

pseuodmembranous colotis, yellow-white plaques (C.difficle)

53
Q

complication of C difficle

A

toxic megacolon

54
Q

new epidemic strain of C difficle attributed for 17% of mortality

A

B1/NAP1

55
Q

treatment for toxic megacolon

A

surgical resection of that part of colon

56
Q

cooked pork, unpasteurized milk, where do u espect the pain to be, what kind of skin lesions manifest?

A

right lower quadrant, erythema nodosum (yersinia enterocolitica)

57
Q

whats the triad for mesentric adenitis, whats its other name

A

fever, RLQ pain, leukocytosis, terminal ileitis

58
Q

seafood/ raw shellfish, produces enterotoxin and inflammatory rx, halophilic, state the agar needed to grow this type of pathogen, and state its name

A

vibrio parahemolyticus, TCBS agar

59
Q

extra intestinal, speticemia, raw oyster ingestion, cellulitis after exposure of wounds to salt water

A

vibrio vulnificus

60
Q

watery diarrhea, dehydration; associated with residence in endemic areas, serotype of V cholera is

A

1

61
Q

diarrhea, fever, nausea, vomiting, blood in stool; often associated with travelerÕs diarrhea, serotype of V cholera is

A

non-01

62
Q

summer, cellulitis in wounds exposed to fresh water

A

aeromonas hydrophilia

63
Q

flask shaped ulcers, liver abscesses, state the order of involvement of this pathogen

A

pathogen: Entamoeba histolytica, order of invovlement: cecum, ascending colon, rectum, sigmoid

64
Q

campers wo donÕt sterilize emountain stream water, homosexuals brih, suspected in prolonged diarrhea, presents with belching and weight loss

A

Giardia lamblia

65
Q

symptoms of giardia lamblia resolve in

A

4-6 weeks

66
Q

sever intractable diarrhea in AIDS pt

A

cryptosporidium parvum

67
Q

nursing homes, winter, state whther this ia s DNA/RNA virus and how can this be demonstrated

A

DNA, ELISA (rota virus)

68
Q

norovius, when does it present, and how can it be demonstrated

A

throughout the year, immune electron microscopy or radioimmunoassay

69
Q

no fever, symptoms last less than 24 hours, potato salad/ice cream

A

staphlococcal food posioning