Major electrolytes Flashcards
the parameter to which the hypothalamus responds
osmolality
osmolality calculation
2xNa + glucose + urea
osmolal gap
indicates the presence of other osmotically active substances
function of sodium
maintain normal water distribution and osmotic pressure of plasma
function of aldosterone
reabsorb Na and water from the urine and excrete K into the urine
function of ADH
increase water reabsorption leading to lower plasma [Na]
reference interval for sodium
135-145 mmol/L
Increase sodium loss, dehydration, increased water retention are causes of
hyponatremia
increase water loss (hormone deficiency), diarrhea, severe burns, or increase dsodium retention are causes of
hypernatremia
major intracellular fluid cation
potassium (K)
physiological function of K
regulation of neuromuscular excitability, contraction of the heart, intracellular fluid volume, H+ ion concentration
causes of hypokalemia
increased K+ loss, decreased + intake, increased movement of K from ECF into ICF
major intracellular fluid cation
K
major extracellular anion
Cl
Chloride is reabsorbed in what part of the kidney
ascending loop of Henle