Cancer screening and monitoring

Question 1

Proteins that are selectively over-produced by and released from cancer cells, but not typically normal cells

Answer 1

Tumor markers

Question 2

Increase in the size of the prostate developed by a large proportion of males

Answer 2

Benign protostatic hyperplasia (BPH)

Question 3

produced in the epithelial cells of the prostate

responsible for liquefaction of semen

Answer 3

Prostate specific antigen (PSA)

Question 4

Major immunoreactive form of PSA is complexed with

Answer 4

a1-antichymotrypsin

Question 5

the free form of PSA represents how much of total PSA

Answer 5

5-40%

Question 6

elevated levels of PSA indicate

Answer 6

malignancy

Question 7

reference values for PSA

Answer 7

Normal: 10 is abnormal

Question 8

low fPSA indicates

Answer 8

prostate cancer

Question 9

oxidation of guaiac by a hydrogen peroxide developer

Answer 9

FOBT, turns blue if heme is present

Question 10

Primary serum tumor marker
Used to aid in detecting recurrence
Almost never elevated in early malignancy

Answer 10

Carinoembryonic antigen (CEA)