Calcium Flashcards
serum total [Ca] is
2.15-2.55 mmol/L
Structural component of bone
Neuromuscular activity
Coenzyme of coagulation factors
Roles of Ca
The active form of Ca is
free Ca
the most important regulator of serum Ca concentrations
parathyroid hormone
function of parathyroid hormone in bone
increases bone resorption and release of Ca and PO4
function of PTH in kidney
increases Ca reabsorption, decreases PO4 reabsorption, increases 1,25(OH)2D formation
function of PTH in intestine
increases Ca and PO4 absorption
Hypocalcemia
hypoparathyroidism
vitamin D deficiency
renal failure
hypoalbuminemia
Hypercalcemia
1’ hyperparathyroidism
malignancy (PTHrP)
low serum PO4
How to measure free calcium
Ion selective electrode (ISE)