MABs Flashcards
1
Q
Eculizumab
A
C5 complement
- treat atypical HUS
- RA
- SLE
2
Q
Omalizumab
A
IgE
3
Q
Mepalizumab
A
IL5
4
Q
Tocilizumab
A
IL6
5
Q
Adalimumab/Infliximab
A
TNF Alfa
- Crohns/IBD
- RA
- Psoriasis
6
Q
Rituximab
A
CD20
- Haemolytic anemia
- B cell malignancy
- Nephrotic syndrome
7
Q
Blinatumomab
A
CD3/CD19
8
Q
Dinutuximab
A
GD2 (neuroblastoma)
9
Q
Basilimab
A
IL2
Prevent GVHD/graft rejection
10
Q
Ocrelizumab
A
Anti CD20 (MS)
11
Q
Dupilumab
A
Anti IL4/13
(eczema, asthma, sinusitis)
12
Q
Cendakimab
A
anti IL 13
13
Q
Benralizumab
A
Anti IL5
14
Q
Imatinib
A
Tyrosine kinase inhibitor (used in Rx of ALL)
15
Q
Abatacept
A
Anti CD80/86 (T-cell signalling)
