M7 Flashcards
What are 2 reasons that cells repoduce
1)Repair/Renew cells/tissues(Mitosis)
2)Create New Individuals(Meiosis)
In What phase does DNA get replicated
Interphase
What is the Cell Cycle
Sequence of events in which a single parent cell divides to produce 2 new daughter cells which then continue the cycle
What is a Genome
A organisms complete set of DNA
What does the DNA of a prokaryotic organism look like
Single Double Stranded DNA in a circle
What does the DNA in a eukaryotic organism look like
Several double-stranded DNA in chromosomes/chromatin
What is the center of a chromosome called?
Centromere
What is the leg of a Chromosome called
Chromatid
Haploid (n/gamete)
one half of chromosome pair
Diploid (2n)
full set of chromosomes
Homologous pairs
Same length, same gene placement in chromosomes
How do you count the number of chromosomes
The number of centromeres
What is a Loci
The location of a gene on a chromosome
Are sex chromosomes a homologous pair
No
What is Phase 1 of mitosis
Interphase
What happens in Interphase
cell growth, replication
What is phase 2 of mitosis
Mitotic Phase
What happens is the mitotic phase
Actual Separation of cells
What are the three phases in interphase for mitosis
G phase = growth, S phase = DNA replicated, G2 phase = final prep
What is the first phase of the mitotic cycle
Prophase
What happens in Prophase
Chromatin turns into chromosomes, Organelles break up/disperse to edges
What is the second stage in the mitotic cycle
Prometaphase
What happens in prometaphase
Nuclear envelope dissolves, Chromosomes attach to kinetochore at centrosomeres
What is the third phase in the mitotic cycle
Metaphase
What happens in the metaphase
chromosomes align at the middle of the cells
What is the 4th phase in the mitotic cycle
Anaphase
What happens in Anaphase
Sister chromatids split apart, cell enlongates into oval
What is the 5th phase in the mitotic cycle
Telophase
What happens in Telophase
First 3 stages in reverse, Cleavage furrow
What happens in Cytokinesis
Ring of micro filaments pull apart cells
What causes Cancer
Uncontrolled Cell division after mutation in gene that codes for cell reproduction proteins
What are the Proto-onco genes
Genes that code for normal cell growth, Mutation = cancer
What do the Tumor suppressor genes do
Slow down cell cycle or tell the cells to dies, Mutations = cancer
What is prokaryotic cell division called
Binary fission
What happens in sexual reproduction
2 haploid cells from parents fuse together to form 1 diploid
What happens in Asexual repdroducion
offspring from single parents(clone
What are the pros of Asexual reproduction
Do not need to waste time finding mates, less energy expended, faster, can produce many more offspring
What are the cons of asexual reproduction
no genetic variation, Adaption difficult, evolve slower
What are the types of Sexual reproduction
Diploid Dominant, Haploid Dominant, Alteration of generations
What is diploid dominant sexual reproduction
Most of life as diploids ex humans
What is Haploid dominant sexual reproduction
Most life as haploids ex fungi
What is Alternation of generations sexual reproduction
Diploid->Haploid->Diploid … most plants
What does Meiosis output
Cell division that results in 4 haploid cells(gametes)
What performs Meiosis
Only performed by germ cells
What are somatic cells
Any other cells that are not germ cells ex blood cells
What are the 3 rounds in Meiosis
Round 1: DNA replication (chromosomes duplication)
Round 2: Meiosis 1
Round 3 Meiosis 2
What happens in Meiosis 1 prophase 1
Homologous pairs line up next to each other then crossover -> recombines the 2 chromosomes.
1st source of genetic variation
What happens in Meiosis 1 prometaphse 1
Micro tubules attach to the diploid chromosome
What happens in Meiosis 1 metaphase 1
Independent assortment into middle of cells, 2nd source of genetic variation
What happens in the 3 last stages of Meiosis 1
Same as Mitosis, Anaphase - pull apart, Telophase - undo organelle stuff, Cytokineses - 2 daughter cells
What happens in meiosis 2
Both the daugher cells go through cell division again (basically mitosis)
What mistakes can happen during cell division
Incorrect # of chromosomes, chromosomes structure rearranged
What is a Karyotype
of chromosomes and apperance of chromosomes
What is nondisjunction
Failed separation during meiosis -> chromosomes duplicated or lost
What is Aneuploid
change in number of chromosomes
What is Euploid
Correct number of chromosomes
What is monosomy
lost chromosome -> inability to survive
What is trisomy
gain chromosome -> Down Syndrome
What is a Barr Body
In females the second X chromosome is shut down. The second X chromosome is always shut down.
Klinefelter(XXY)
One is barr body, Can cause reduced body hair
Triple X (XXX)
2 Barr bodies, Leads to Development delays and reduced fertilatity
Chromosome rearragements
Duplication/deletion/inversion/translocation in replication leading to development/ physical changes