M6: HIV Flashcards
1
Q
human immunodeficiency virus morphology
A
- linear
- single stranded
- enveloped
- RNA
- ~10K nucleotides long
- conical capsid
2
Q
unique traits of HIV
A
- capsid contains 2 copies of RNA
- capsid contains ~2000 copies of viral protein p24
3
Q
key glycoproteins in HIV’s viral envelope (2)
A
- gp 120
- gp 41
4
Q
gp 120
A
- glycoprotein in HIV viral envelope
- binds to host’s protein receptors, which allows gp 41 to do its job
5
Q
gp 41
A
- glycoprotein in HIV viral envelope
- binds with host’s chemokine receptors
6
Q
gp 41 binds with (2)
A
CXCr4 or CCR5
7
Q
reverse transcriptase (RT)
A
HIV protein that acts on RNA copies once in host cell to generate complimentary viral DNA strands
8
Q
anti retroviral medication
A
used in people with HIV to stop virus from reproducing
9
Q
AIDS
A
- aka Acquired Immunodeficiency Syndrome
- results from untreated HIV infection
- characterized by severe loss of bodily immune system, causing person to die via opportunistic infections
10
Q
people who’ve died from AIDS
A
35 million
11
Q
people living with HIV
A
37 million
12
Q
AIDS discovered in
A
1981
