Lymphoproliferative disease Flashcards
1
Q
Common presentation of lymphomas
A
Increased lymphocyte count, pt otherwise well, enlarged LNs +/- B sx
2
Q
NHL
A
B cell
Aggressive or indolent
Indolent is not curable
Tends to affect older people
3
Q
Why can’t you use rituximab for T cell NHL
A
Ritucimab targets CD20 which is only on B cells
4
Q
What type of cell are Reed-Sternberg cells?
A
Macrophages
5
Q
HL
A
Bimodal pattern
Painless, non-tender, asymmetrical LNs
6
Q
Why is LDH elevated in lymphoma?
A
Released when cells broken down
7
Q
Treatment for diffuse large B cell lymphoma
A
Out-pt RCHOP