LYMPHOID SYSTEM Flashcards

1
Q

what is the lymphoid system?

A

a sort of ‘overflow’ system that provides for the drainage of surplus tissue fluid and leaked plasma proteins to the bloodstream, as well as for the removal of debris from cellular deposition and infection

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2
Q

what is the order of lymphatic drainage?

A

lymphatic capillaries —> lymph vessels —(lymph nodes)—> lymph trunks —> thoracic duct/right lymphatic duct —> venous angle

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3
Q

what is the venous angle?

A

junction between the subclavian and internal jugular veins

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4
Q

what trunk do the head and neck drain to?

A

jugular trunk

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5
Q

what trunk does the upper limb drain to?

A

subclavian trunk

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6
Q

what trunk do the lungs, heart, trachea, and mediastinum drain to?

A

bronchomediastinal trunk

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7
Q

what trunk do the lower limbs, pelvis, and kidneys drain to?

A

lumbar trunk

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8
Q

what trunk do the intestines drain to?

A

intestinal trunk

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9
Q

what is a lymphatic plexus?

A

a network of lymphatic capillaries that originates blindly in the extra cellular (intracellular) spaces of most tissues

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10
Q

what allows plasma proteins, bacteria, cellular debris, and even whole cells (esp. lymphocytes) to readily enter lymphatic capillaries?

A

lymphatic capillaries are formed of a highly attenuated endothelium lacking a basement membrane, along with a surplus of tissue fluid

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11
Q

describe lymphatic vessels

A

= thin-walled vessels with abundant lymphatic valves that compromise a nearly body-wide network to drain lymph from the lymphatic capillaries

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12
Q

what gives lymphatics a beaded appearance?

A

the vessels bulge where each of the closely spaced valves occur giving it a beaded appearance

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13
Q

what are lymphatic trunks?

A

large collecting vessels that receive lymph from multiple lymphatic vessels

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14
Q

where are lymphatic vessels and capillaries NOT found?

A

teeth, bone, bone marrow, the CNS

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15
Q

where does tissue fluid from the CNS drain into?

A

cerebrospinal fluid

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16
Q

what is lymph?

A

the tissue fluid that enters lymph capillaries and is conveyed by lymphatic vessels. usually clear, watery and slightly yellow. has a similar composition to blood plasma

17
Q

what are lymph nodes?

A

small masses of lymphatic tissue located along the course of lymphatic vessel. where lymph is filtered on its way to the venous system

18
Q

what are lymphoid organs?

A

parts of the body that produce lymphocytes

19
Q

what traverses lymph nodes?

A

deep and superficial lymphatic vessels as they course proximally. become larger was they merge with vessels drinking adjacent regions

20
Q

right lymphatic duct

A
  • drains lymph from the body’s right upper quadrant (right side of head, neck and throat plus the right upper limb)
  • at the root of the neck, it enters the right venous angle
21
Q

what is the right venous angel?

A

the junction of the right internal jugular and right subclavian veins

22
Q

thoracic duct

A

drains lymph from the rest of the body. the lymphatic trucks draining the lower half of the body merge in the abdomen, sometimes forming a dilated collecting sac, the cisterna chyli —> from this sac (if present), or from the merger of the trunks, the thoracic duct ascends into and then through the thorax to enter the left venous angle

23
Q

what is the left venous angle?

A

the junction of the left internal jugular and left subclavian veins

24
Q

name 2 additional functions of the lymphoid system

A
  1. absorption and transport of dietary fat

2. formation of a defence mechanism for the body

25
Q

name 8 lymph node groups

A
  1. cervical (neck)
  2. mesenteric
  3. axillary (armpit)
  4. cubital
  5. iliac
  6. inguinal (groin)
  7. lumbar
  8. popliteal
26
Q

what is primary lymphoid tissue?

A

red bone marrow + the thymus gland

27
Q

primary lymphoid tissue functions

A
  • where lymphocytes are formed and mature
  • provide an environment for stem cells to divide into B and T cells
  • both B and T cells are ‘born’ in bone marrow
  • B cells mature in bone marrow whereas T cells mature in the thymus
28
Q

secondary lymphoid tissues

A

lymph nodes, tonsils, Peyer’s patches, musosa associated lymphoid tissue (MALT)

29
Q

functions of secondary lymphoid tissues

A
  • a series of filters monitoring the contents of the extracellular fluids (ie. lymph, tissue fluid, blood)
  • where lymphocytes are activated
30
Q

what are Peyer’s patches?

A

large masses of confluent lymphoid follicles found in the walls of the ileum.