Lymphatics

Question 1

What parts of the body are drained by which major duct?

Answer 1

Right lymphatic: RA, R thorax, Right head/neck

Thoracic Duct: Everywhere else

Question 2

What rate the specific markers for T and B lymphocytes in flow cytometry?

Answer 2

All: CD45

All T: CD3

AllB: CD19

HelperT: CD4

CytotoxicT: CD8

ActivatedT: CD25

Question 3

What are APGs?

Answer 3

Antigen presenting cells

• Mo
• Dendritic cells
• B Cells
• Neutrophils

Question 4

Where does the originate from?

Answer 4

3rd pharyngeal arch

Question 5

What are Hassan’s Corpuscles?

Answer 5

Concentrically arranged thyme epithelial Cells which assist regulatory T Cells

Question 6

Where do B cells maturation n the lymph node?

Answer 6

In the germinal center of secondary follicle

Question 7

What is a Peters Patch?

Answer 7

Type of MALT in GI

Question 8

What are the roles of M cells in MALT?

Answer 8

Assist in transportation of pathogens

Question 9

Differentiate the Peyers patch tissue in the pharynx vs palat

Answer 9

• Pharyngeal tonsil (adenoids) – pseudostratified ciliated
epithelium
• Lingual and palatine – stratified squamous epithelium

Question 10

Differentiate cells of cortex vs paracortex of Lymph nodes

Answer 10

Cortex -> B cells and FDCs

Paracortex —> T cells and HEVs for extravasion

Question 11

Describe the two regions of the spleen

Answer 11

White pulp (20%) - Leukocytes, PALS (T CElls), and Lymph nodules Of B Cells

Red Pulp - RBCs

Question 12

What is the blood flow entering the spleen?

Answer 12

Splenic artery -> Trabecular artery -> Ventral artery -> Penicillar arterioles

Question 13

What is the flow of fluid through the lymph node?

Answer 13

Afferent lymph vessel -> Subcapsular sinus -> Trabecular sinus -> Medullary sinus -> Efferent lymph vessel