GI Embryo Flashcards

1
Q

What is the Vitelline duct?

A

Narrow connection of the midgut to the yolk sac

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2
Q

What is the Cloaca?

A
  • Expanded region of Hindgut

- Membrane coverings future butthole

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3
Q

What forms the foregut region?

A

Mouth to Proximal duodenum

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4
Q

What forms the midgut?

A

Distal Small intestine to proximal 3/2 of transverse colon

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5
Q

What makes up the hindgut?

A

Last 1/3 transverse colon to anal canal

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6
Q

What is the blood supply and innervations of the foregut?

A

Blood: Celiac Trunk

Parasympathetic: Vagus
Sympathetic Pregang: Greater Splanchnic
Symp Postgang: Celiac ganglion

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7
Q

What is the blood supply and innervations of the Midgut?

A

Blood: Superior mesenteric artery

Parasympathetic: Vagus
Sympathetic Pregang: Lesser Splanchnic Nerves
Symp Postgang: Superior Mesenteric Ganglion

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8
Q

What is the blood supply and innervations of the hindgut?

A

Blood: Inferior mesenteric artery

Parasympathetic: Pelvic splanchnic nerves
Sympathetic Pregang: Lumbar Splanchnic Nerves
Symp Postgang: Inferior Mesenteric Ganglion

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9
Q

What is Atresia?

A

Absence or closure of an orifice or passage

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10
Q

What is the most common atresia in a developing fetus?

A

Duodenal atresia

  • Enlarged uterus f/ polyhydramnios
  • Distended stomach and duodenum up to atresia
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11
Q

Which week does the respiratory bud appear?

A

Week 4

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12
Q

What is the most common defect is the respiratory system in the developing fetus?

A
  • Trachoesophageal fistula in distal third of trachea
  • Blind ending of esophagus
  • Polyhydramnios
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13
Q

What is the most common defect is development of liver and gallbladder?

A
  • Failure Of bile ducts to develop or recanalize —> Biliary atresia/stenosis
  • More Common in extrahepatic ducts
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14
Q

What is an annular pancreas?

A

when the ventral pancreatic bud splits and encircles the duodenum (forming a ring), constricting the lumen, leading to duodenal stenosis or atresia.

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15
Q

What is congenital pyloric stenosis?

A

Hypertrophy of the smooth muscle of the pyloric sphincter of the stomach wall.

1 in 150 males

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16
Q

When does the midgut herniate? Retract?

A

Week 5

Retracts around week 9-0

17
Q

What degree rotation occurs in midgut herniation?

A

270 degrees

18
Q

What can happen in malrotation of the gut?

A

Superior Mesenteric Artery obstructs —> Gangrene in infarcted region

19
Q

What is a volvulus?

A

an abnormal twisting the GI tract causing bowel obstruction.

20
Q

Differentiate Omphalocoele and Gastroschisis.

A

Omphalocoele: Midgut loops fail to return to abdominal cavity
- Covered by amniotic membrane

Gastoschisis: Defective lateral folding of embryo; Ventral abdominal wall is weak and viscera herniate into amniotic cavity

21
Q

What is Hirschprung’s disease?

A
  • Congenital Megacolon
  • Defectiv eNC migration of parasympathetic neurons
  • Defective smooth muscle contraction