lymphatics Flashcards
majority of the lymph drainage into what duct? then into?
thoracic duct then into the left subclavian vv
lymph nodes relative vessels in and out
LN have multiple vessels returning lymph entering them but only one vessel leaving to return the fluid to circulation
typical lymph drainage pattern from the oral cavity, exception
usually down and in towards the internal jugular, crossover can occur but not always
why is SCC common in the floor of the mouth
common with tobacco use and alcohol> mostly accumulate on the floor of the mouth=increased exposure
typical lymph drainage patterns at the tongue
ant 2/3: anterior drainage
post 1/3: posterior drainage
lymph nodes/gland confusion
entirely possible to palpate a mass and have it be either a LN or gland as the salivary glands often have LN associated with them
staging and grading tumors, primary indicator?
- Stage and grade determine prognosis
- Staging reflects the clinical extent of the tumor
- Grading a tumor reflects its histologic subtype
- Of the two, staging is the primary indicator of prognosis
grading tumors
- Degree of differentiation exhibited by cells
- How closely cells resemble normal tissue structure
- Grade I – low grade
- Grade II – moderately differentiated
- Grade III – poorly differentiated
staging tumors
- Based upon the size and extent of metastatic spread of the lesion
- Tumor-node-metastasis (TNM) system used for most cancers
Staging – TNM system components
- Size, in cm, of the tumor (T)
- Involvement of lymph nodes (N)
- Presence or absence of distant metastasis (M)
T of staging classes
TX: No information available on primary tumor
T0: No evidence of primary tumor/ tumor not found
Tis: Carcinoma in situ at primary site
T1: Tumor less than 2 cm
T2: Tumor 2-4 cm in diameter
T3: Tumor greater than 4 cm
T4: Tumor has invaded adjacent structures
Staging – “N” classes
NX: Nodes not assessed
N0: No clinically positive nodes (not palpable)
N1: Single clinically positive ipsilateral (on same side) node less than 3 cm
N2: Single clinically positive ipsilateral node 3 to 6 cm; or Multiple ipsilateral nodes with all less than 6 cm; or bilateral or contralateral nodes with none greater than 6 cm
N3: Node or nodes greater than 6 cm
Staging – “M” classes
MX: Distant metastasis not assessed
M0: No distant metastasis
M1: Distant metastasis is present
Stage 0 TMN classes
0 Tis, N0, M0
stage 1 TMN classes
T1 N0 M0