Lymphatic System Flashcards
What is interstitial fluid
It is the ultra filtrate of blood
What does hydrostatic pressure do
It pushes fluid into capillaries
What does blood colloid osmotic pressure do
It pulls fluid into capillaries
The fluid remains in the interstitial space passes into lymphatic capillaries as ?
Lymph
What are the 3 core functions of lymphatic vessels
Drains excess interstitial fluid (takes it back to the blood )
Transports dietary lipids
Carries out immune responses
Where are lymph vessels not found
A vascular tissue ,CNS ,Bone marrow
What do the mini valves in lymphatic vessels do
They allow fluid to enter when pressure outside the vessel increase but not in reverse
Do large vessels have mini valves
No they do not they have one way valves that assist with the return of lymph to general circulation
What are the main lymphatic trunks
Jugular Subclavian Bronchomediastinal Intestinal Lumbar
What is the mechanism of flow in the lymphatic circulation
Lymphatic capillaries ,lymphatic vessels ,lymph nodes ,lymph trunks ,Lymph ducts ,blood
What are the two lymph ducts
Right lymphatic and the thoracic
What are the primary lymphatic organs
Where stem cells divide and become immunocompetent they include red bone marrow and thymus
What are secondary organs
Sites where most immune responses occur
Includes spleen ,lymph ,nodules ,lymph nodes
What is the function of the thymus
Proliferation and maturation of T cells
What happens to mature T cells in the thymus
They leave the thymus via the blood stream and migrate to other lymphoid organs
Each lobe of the thymus has lobules ,what types of cells are found in the cortex of the lobules
Large number T cells , dendritic cells ,epithelial cells and macrophages
What do dendritic cells do
They assist in maturation of T cells
What do the epithelial cells in the cortex do
They educate T cells
What cells are found in the medulla of the lobules
Few T cells ,dendritic cells ,epithelial cells , and macrophages
What is the Hassals corpuscles
Remnants of the epithelial cells and they are filled with keratohyalin deposits
What are lymph nodes responsible for
For filtration of lymph
Where are lymph nodes located
Located along the lymphatic vessels, occurring in clusters ,eg by axillary ,cervical and inguinal regions
What cells are in the lymph nodes lobules cortex
Densely packed with B cells
What do B cells proliferate and differentiate into
Plasma cells and memory cells
What is in the medullary cords
b lymphocytes ,anti body producing plasma cells and macrophages
What is in the medullary sinuses
Reticular fibers ,lymphocytes ,macrophages
What is metastasis
Spread of disease from one part of the body to another and it can happen via lymphatic vessels
What are cancerous Lymph nodes like
They are enlarged ,firm ,non tender and establish new tumors where they lodge ,they are fixed
What is the stroma of the spleen
Capsule ,trabeculae , reticular fibers
What parts form part of the parenchyma of the spleen
Red and white pulp
What is the function of the spleen
Removes worn out and damaged RBCs and platelets
Storage of platelets
Hemopoiesis during fetal life
What forms part of the white pulp in the spleen
Lymphocytes and macrophages suspended on reticular fibers surrounding central artery
What forms part of the red pulp of the sple
Venous sinuses
Splenic cords
Do lymphatic nodules have a capsule
No ,lymphatic nodes have one
Where can we find lymphatic nodules
Mucous membranes lining the GI ,urinary ,reproductive,and respiratory tract
What are tonsils
Collections of lymphocytes tissue around aero digestive tract
What are the three types of tonsils
Pharyngeal
Palatine
Lingual
What are lymphocytes
Warriors of the immune system
What do B cells do
The protect the body against antigens
What do T cells do
They manage immune responses and some of the, directly attack and destroy infected cells
What are reticular cells
They are fibroblast like cells that produce the reticular fibers stroma which is the network that supports the other cell types in the lymphoid organs
Lymphoid tissue have which cell types
B and T cells ,reticulocytes , macrophages,lympcocyte cells ,dendritic cells
What are lymphoid tissue fiber type
Reticular fibers