lymphatic system Flashcards

1
Q

Lymphatic system

A

organ system that is part of immune system and complementary to the circulatory system

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2
Q

lymph

A

-fluid leaked from blood vessels, bathes the tissue and goes back to the blood stream
-colorless(lacks RBC) fluid contenting WBC

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3
Q

lymphatic vessels and capillaries

A

-thin-walled vessels
-endothelia cells and smooth muscle

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4
Q

interstital fluid

A

-fluid around the cells
-flow into lymphatic capillaries, following pressure gradient

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5
Q

bone marrow produces?

A

-lymphacytes(immature T cells, B cells, NK cells)

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6
Q

Thymus?

A

-responsible for maturation of T cells

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7
Q

Lymph nodes?

A

-Bean shaped structures along lymph vessels
-filter substances that travel through lymphatic fluid

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8
Q

spleen?

A

-Synthesis and maturation of lymphocytes(B and T cells)
-filter blood
-stores blood cells
-stores platelets
-recycles iron
-destroys old blood cells

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9
Q

tonsils?

A

-protection of pharynx against pathogens

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10
Q

Appendix

A

-protection of the large intestine

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11
Q

Mucosa

A

associated lymphatic tissues (MALT) in digestive, respiratory, unitary, reproductive tracts

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12
Q

lymphocytes

A

-T cells(most common)
-B cells
-natural killer (NK) cells
-synthesized in bone marrow,

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13
Q

T cells

A

-Killler T cells (thymus derived cells)
-attack and destroy foreign cells or body cells infected
-direct cellular attack

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14
Q

NK cells

A

-attack foreign cells or body cells infected
-secrete chemicals that lyse the plasma membrane of the abnormal cells
-more rapid response

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15
Q

B cells

A

-activated by Helper T cells
-differentiate into plasma cells or memory B cells
-plasma cells secrete antibodies, leads to destruction of pathogens
-memory B cells remember the antigen

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16
Q

helper T cells

A

-stimulate the responses of both T and B cells
-no helper T cells to stimulate B cells then no antibodies
-no helper T cells to stimulate T cells then no active T cells to kill pathogens

17
Q

Regulatory T Cells

A
  • moderate the immune response
    -wind down immune response by deactivating B and T cells
18
Q

Memory T cells

A

-respond to antigens they have already encountered by cloning
-reserve population of T cells that can respond explosively to a subsequent exposure to their antigen

19
Q

Macrophage

A

-large, active phagocytes
-present everywhere in body
-WBC that can engulf a pathogen, destroy target by releasing toxic chem into interstitial fluid, bind to pathogen in interstitial and destroy it

20
Q

Primary response

A

-1st exposure to antigen
-few B cells activated
-antibody level increases over a period of 10 days

21
Q

Secondary response

A

-exposure to the same antigen
-memory B and T cells are respond aggressively
-produce lots of antibodies faster

22
Q

Innate immunity

A

-non specific
-born with it
-skin, phagocytes

23
Q

Naturally acquired innate immunity

A

-baby receives antibodies from mother

24
Q

Artificially acquired innate immunity

A

-person receives antibodies to fight infection

25
Q

Adaptive immunity

A

-specific
-T and B cells respond to specific antigens

26
Q

antibody-mediated (humoral) immunity

A

-antigen-specific antibodies produced by B cells

27
Q

Cell-mediated immunity

A

-primarily driven by mature T cells, macrophages doesn’t depend on antibodies

28
Q

Naturally acquired adaptive immunity

A

-occurs after exposure to antigens in environment

29
Q

artificially acquired adaptive immunity

A

-vaccination or immunization

30
Q

anaphylaxis

A

-server allergic reaction or hypersensitive response to antigen
-memory B cells remember the antigen
-tigger massive release of histamine