Lymphatic system Flashcards

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1
Q

Function of the lymphatic system

A
  • maintains balance of fluids and fights infection
  • absorb macromolecules that cannot go into the capillaries
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2
Q

How do things flow in the lymphatic system and where do they drain

A
  • pressure drives this system but there are some small muscles
  • skeletal muscle contraction can help
  • right UE + head = right subclavian
  • everything else = left subclavian
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3
Q

What are the components of the lympathic system

A
  • lymph vessels
  • lymph nodes
  • spleen
  • thymus gland
  • tonsils
  • peyer’s patches (small intestine)
  • lymphocytes
  • bone marrow
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4
Q

Fluid exchange with capillaries and lymph vessels

A
  • in CV system most filtrate reabsorbed at venous end
  • 2-3% is NOT picked up
  • this excess is transported as lymph in lymphatic vessels (use of valves)
  • any fluid that exceeds the capacity of the venous removal is picked up by the lymphatics
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5
Q

lymphangitis: defintion

A
  • inflammation of the lymphatic vessel
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6
Q

lymphadenitis: defintion

A
  • inflammation of one or more lymph nodes
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7
Q

lymphedema

A
  • an increased amount of lymph fluid in the soft tissues
  • results in accumulation or protein rich fluid in EXTRACELLULAR spaces
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8
Q

lymphadenopathy

A
  • enlargement of the lymph nodes
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9
Q

Lymphedema cause

A
  • decreases lympathic transport capacity or increased lympathic load/blockage
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10
Q

Stage 0 lymphedema

A
  • Lymph transport capacity is reduced;
  • no clinical edema present;
  • symptomatic complaints possible
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11
Q

Stage 1: lymphedema

A
  • Accumulation of protein rich, pitting edema
  • Reversible with elevation
  • Area affected may be normal size on walking in the morning
  • Increases with activity, heat and humidity
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12
Q

Stage 2: lymphedema

A
  • accumulation of protein rich non-pitting edema with CT scaring
  • Irreversible
  • Does not resolve overnight
  • Increasingly more difficult to pit
  • Clinical fibrosis is present
  • Skin changes present
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13
Q

Stage 3: lymphedemia

A
  • Lymphostatic elephantiasis
  • Accumulation of protein-rich edema with significant increase in connective and scar tissue.
  • Severe non pitting fibrotic edema.
  • Atrophic changes (hardening of dermal tissue, skin folds, skin papillomas, and hyperkeratosis
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14
Q

Usualy signs and symptoms of lymphedema

A
  • Slow onset, progressive
  • Pitting (early stages)
  • Stemmer’s sign positive (try to pinch and can’t = positive)
  • Dorsum of foot buffalo hump
  • Rarely painful, however discomfort (heaviness and achiness) is common
  • Skin changes in the LE lymph-edema may include hyperkeratosis, papillomas
  • In contrast with venous disease the skin maintains hydration and elasticity for longer in the disease process
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15
Q

What can go along with lymedema

A

-Cellulitis is common due to back up of fluid

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16
Q

Edema grading scale

A
  • Grading scale for pitting edema
    1+ there is barely detectable 2 mm depression; not easily seen but can be felt. Immediate rebound
    2+ There is a 4 mm deep pit. A few seconds to rebound
    3+ there is a 6 mm deep pit. 10-12 seconds to rebound
    4+ There is an 8 mm deep pit ( very deep) > 20 seconds to rebound
17
Q

Lymph Angiodysplasia:

A
  • Varicosity
  • Hema-angioma: discolorations; vessels stretched
  • Neurological changes due to increase pressure
18
Q

Pathogenesis of lymphedema: decreased absorption of lymph

A
  1. intralympathic pressure increases
  2. lymph oozes into the wall of the lymphatics and into the perilymphatic tissues
  3. lymphangiosclerosis (hardening)
  4. lymph pump deterioration
  5. low output failure: lymphedeme
19
Q

Pathogenesis of lymphedema: subtotal lympatic blockage

A
  1. remaining lympathics increase their pumping activity
  2. intralympathic pressure increases
  3. Dilation of valvular insufficiency
  4. lymph oozes into the wall of the lymphatics and into the perilymphatic tissues
  5. lymphangiosclerosis (hardening)
  6. lymph pump deterioration
  7. low output failure: lymphedeme
20
Q

Clinical manifestations of Lymphedema

A
  • positive stemmers sign
  • full, heavy, tight sensation
  • numbness, burning, aching, pain
  • decreased flexibility
  • difficulty with clothing/jewelry fitting
  • increased girth and weight
  • impaired speech, swallowing respiration (Swelling in face/neck)
  • atrophic skin cahnges
21
Q

Complications of lymphedema

A
  • atrophic skin changes
  • keratotic patches
  • lymphatic fluid leakage
  • toe fungus
  • functional impairments
22
Q

Medical management of lymphedema: diagnosis

A
  • primary = stemmers sign
  • secondary = medical history
  • unilateral = doppler US
  • CT/MRI
  • lymphoscintigraphy (dye - newer)
  • fluorescence lymphography
  • magnetic resonance lymphangiography
23
Q

medical management of lymphedema treatment

A
  • coordinated care
  • medication s
  • surgery to debulk
24
Q

PT clinical assessment with lymphedema

A
  • caution with BP cuff
  • Thorough history and systems review
  • skin assessment
  • pain, paresthesias, sensory impairments
  • photographs
  • functional impairments
25
Q

Lymphedema PT interventions

A
  • manual lymph drainage
  • multilayer short-stretch compression bandaging
  • exercise (muscle pumping)
  • Compression garments
  • compression pumps
  • education
  • psychological and emotional support
26
Q

Comprehensive Lymphedema management:

A
  • Initially intensive phase
  • Once it is stage 2 it is not reversible
  • Optimization (maintence) phase
  • Manual lymph drainage
  • Compression badaging
  • Short-stretch compression bandaging
  • Long-stretch compression bandaging
  • Maintaining proper pressure gradient
  • Exercise guidelines
  • Compression garments
  • Education and home program
  • Importance and adherence
  • Compression pumps: intermittent - - - Pneumatic compression
  • Skin care
  • Guidelines for job and lifestyle modifications
  • Psychosocial considerations and quality of life
  • Low level laser therapy
27
Q

Lymphagenitis/lymphangitis and cellulitis medical management

A
  • diagnosis Hx
  • treament:
  • rest immobilization, cold
  • oral antibiotics or IV
28
Q

Lipedema clincal manifestations

A
  • symmetric swelling from fatty deposits from hips to ankles
  • primarily women
  • bruisability due to pressure breaking capillaries
  • pain/heavy feeling
  • orthostatic edema
  • dieting does not change tissue
29
Q

lipedema stage 1

A
  • skin soft and regular
  • palpable nodules (fatty deposits)
30
Q

lipedema stage 2

A
  • skin soft and regualr
  • nodules tought, fatty lobules
  • pitting edema
  • skin color changes
31
Q

stage 3 lipedema

A
  • massive fat deposition
32
Q

Lipedema medical management - diagnosis

A
  • diagnosis:
  • (-) stemmers sign
  • symmetric swelling
  • dieting doesnt help
  • lymphoscintigram (dye)
33
Q

lipedema medical mangement - treatment

A
  • symptomatic relief
  • functional improvement
  • compression garments
34
Q

Venous edema

A
  • some pittin g
  • brawny
  • hemosiderin staining
  • ulcers medial malleolus
  • fibrosis of subcutaneous tissue
  • atrophic skin
35
Q

Acute deep vein thrombosis clinical manifestation s

A
  • sudden onset
  • unilateral
  • cyanosis
  • positive homans sign
  • potentially lethal disease
  • venous doppler (US)
36
Q

Congestive heart failure Clinical manifestations

A
  • edema is greatest distally
  • pitting edema always bilateral
  • complete resolution with elevation (early)
  • no pain
  • orthopnea, PND, dyspnea on exertion
  • jugular venous distension
37
Q

CHF diagnosis

A
  • physical exam,
  • CXR
  • cardiac echo
38
Q

Malignant lymphedema

Clinical manifestations

A
  • pain, paresthesia, paralysis
  • central location (proximal onset)
  • rapid development, continuous progression
  • swelling and nodules in supraclavicular fossa
  • hematoma like discoloration
  • ulcers, non-healing wounds
  • recurrent malignancy
  • sole presenting symptom of new malignancy
39
Q
A