Integumentary Flashcards
What is the skins function
- Largest organ 15-20% of body weight
-Function = protection (keeps insides in and outside things out)
Primary vs secondary lesions (skin)
- Primary lesions: happen on the skin
- Secondary lesions: could be the result of another issue (ie. Cancer, liver dysfunction)
- Inspection and history!
Parts of the epidermis and their functions?
- Stratum corneum: functions in protection and barrier
- Keratinocytes: function in synthesis of keratin (skin protein)
- Langerhan cells: function in antigen presentation/immune response
- Basal cells: function in epidermal reproduction
What is the dermis layer of the skin made of and it’s function
Collagen, reticulum, elastin: function in skin proteins, skin texture
Dermis cells and their function
- Fibroblasts: function in collagen synthesis for skin strength and wound healing
- Macrophages: function in phagocytosis, inflammation and repair
- Mast cells: function in providing histamine for vasodilation and chemotactic factors for inflammatory response
- Lymphatic glands: removal of microbes and excess interstitial fluids; provide lymphatic drainage
- Blood vessels: provide metabolic skin requirements thermoregulation
- Nerve fibers: perception of heat, cold, pain and itching
Appendages of the epidermal layer and their functions
- Excrine unit: function in thermoregulation by perspiration
- Apocrine unit: function in production of apocrine sweat
- Hair follicles: function in production of hair, cavity encoding hair
- Nails: function in protection, mechanical (fine motor) assistance
- Sebaceous glands: function in producing sebum (oil) to lubricate skin)
Subcutaneous tissue (what is it?)
- Adipose: function in energy storage and balance, trauma absorption
- Lose this during aging
Signs and symptoms of skin disease
- pruritus
- Xerosis
- urticaria
- rash
- blisters
- xeroderma
- edema
- discoloration
Pruritus
- itching *primary sign of integumentary disease
Xerosis
rough dry skin
Urticara
- hives
- can be caused by stress and anxiety
- wheals
rash
- Erythema: redness
- Macular lesions: hives, red, raised
- Papular: bubble
blisters
- Vesicle or bulla (fluid accumulation)
Xeroderma
- ichthyosis (excessive dryness) flaky
Normal aging with the skin
Hormone changes
Environmental factors
Lifestyle
Normal aging:
- Structure-epidermis, dermis, appendages
- Functional changes in each layer
- Hair: texture goes from finer → stiffer
- Hair Location: pits, genitals
- hair Color: lighter → darker
- Turgor: pinch test – should go back immediately
- Vasculatory: tend to have less peripheral circulation (cold