Infectious diseases Flashcards
What are signs and symptoms of infectious disease
- systemic symptoms: fever, chills, malaise, nausea and vomiting
- 102º rule, divides conditions into two groups
what can a fever > 104 cause
delirium or seizures
acute infection fever
- lasts 7-10 days and goes up and down
sepsis and ongoing infections - Fever
> 10 days and up to 3 weeks
intermittent fever
temperature goes to normal within 24 hours (may come back)
Remittent Fever
fluctuates but not back to normal (normal with viral infections)
Sustained or continuous Fever
remains above normal within minimal variations
Recurrent or relapsing fever
fever for a few days and then goes away but then comes back
integumentary symptoms of infectious disease
- Purulent drainage from abscess, open wound or - skin lesion
- Skin rash, red streaks
- Bleeding from gums or into joint: Joint effusion or erythema
Cardio symptoms of infectious disease
- Petechial lesions
- Tachycardia (see aneurysm and thrombophlebitis)
- Hypotension
- Changes in pulse rate (may increase of decrease)
CNS symptoms of infectious disease
- Altered level of consciousness, confusion, seizures
- Headache
- Photophobia
- Memory loss
- Stiff neck, myalgia
GI symptoms of infectious disease
- Nausea
- Vomiting
- Diarrhea
GU symptoms of infectious disease
- Dysuria or flank pain
- Hematuria
- Oliguria
- urgency , frequency to use the bathroom
Upper respiratory tract symptoms of infectious disease
- tachypnea/dyspnea
- Cough
- Hoarseness
- Sore throat
- Nasal drainage
- Sputum production
- Oxygen desaturations
- Decreased exercise tolerance
- Prolonged ventilatory support
Why are older adults more susceptible to infections
- Changes in cell-mediated or t-cell and b-cell function
- Experience increased morbidity and mortality
- Need for additional vaccines and boosters
Infection defintion
an organism establishes a parasitic relationship with host (begins with transmission of an infectious organism)
What are the three outcomes of an infection
- Contaminate the body surface and be destroyed by first line of defense
- A subclinical infection may occur causing immune response of the host
- A clinically apparent infection - one or more clinical symptoms, infectious disease
More involve
The early it is caught the easier to resolve
Colonization
pathogen presented in host but host is asymptomatic
Incubation period
time between pathogen entering host and appearance of clinical symptoms
Latent infection:
after microorganism has replicated but remains inactive in host
Period of communicability:
this time period when an organism can be shed and infect others through direct or indirect contact
Types of organism
- virus
- mycoplasmas
- bacteria
- Rickettsiae
- chlamydiae
- Protozoa
- fungi
- prions
Mycoplasmas
are unusual, self-replicating bacteria that have no cell wall components and very small genomes
Rickettsiae:
primarily pathogens transmitted through a bite (mosquitoes and tics)
Chlamydiae:
require host cells for replication contain DNA and RNA
- susceptible to antibiotics
Protoza:
a single cell or group of non differential cells loosely held together and not forming tissues
Fungi:
are unicellular to filamentous organisms possessing hyphae (filamentous outgrowths) surrounded by cell walls and containing nuclei
Prions:
proteinaceous, infectious particles consisting of proteins but without nucleic acids
- transmitted from animal to humans
HAI
- Healthcare acquired infection aka nosocomial infections are infections acquired during hospitalization
- Joint infections
- Don’t have it going in but you get it going out
Reservoir
an environment in which an organism can live and multiply
The portal of exit:
place where parasites leaves reservoir (secretions, fluids, excretions)
Mode of transmission: routes
- Contact (direct or indirect)
- Airborne
- Droplet
- vehicle/vector borne
Portal of entry - examples
ingestion, inhalation, bites, or through contact with mucous membranes, percutaneously or transplacentally
What are the 3 lines of defense for the host
- external
- inflammatory process
- immune response
Principle pathogens:
regularly cause disease in people with apparently intact defense systems