lymphatic system Flashcards

1
Q

how does lymph differ from plasma?

A

lymph contains white blood cells

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2
Q

lymph might carry __________ from a site of infection and ______ cells from cancerous tissue.

A

bacteria
tumor

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3
Q

why can we see lymph after a high fat meal?

A

in the gut, the lymph is rich in lipids

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4
Q

why prevents backflow in lymph?

A

valves

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5
Q

where does lymph get filtered at?

A

lymph nodes

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6
Q

what vessels join to form larger lymph vessels?

A

efferent

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7
Q

where does lymph ultimately drain into that empties into the cranial vena cava and mixes with the blood stream?

A

thoracic duct

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8
Q

what is the primary lymphoid organ that T lymphocytes originate from?

A

thymus

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9
Q

what is the primary lymphoid organ which generates T and B lymphocytes and macrophages?

A

bone marrow

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10
Q

list secondary lymphoid organs

A

GALT, BALT, MALT (tonsils, adenoids), spleen, lymph nodes

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11
Q

Except for the thymus, lymphocytes in all these organs are organized into nodular structures called ________ or they can be found dispersed diffusely in the organ/tissue

A

follicles

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12
Q

what part of the thymus do mature T lymphocytes reside?

A

cortex

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13
Q

what part of the thymus do immature T lymphocytes reside?

A

medulla

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14
Q

what cells make up the framework of lymphoid organs?

A

stromal cells

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15
Q

In the thymus, the stromal cells called _________________ form whorls called “______________”.

A

epithelial reticular cells,
Hassal’s corpuscles

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16
Q

Hassal’s corpuscles are apparent in the medulla of thymus from older animals as the thymus ________

A

atrophies

17
Q

what are examples of secondary lymphoid organs?

A

lymph nodes and spleen

18
Q

what is the cortex of the lymph nodes filled with?

A

follicles

19
Q

what do the follicles have of the lymph node that is made of mature B lymphocytes?

A

mantle zone

20
Q

the inner core of the follicles of lymph nodes have what that is made of immature B lymphocytes?

A

germinal center

21
Q

in the cortex of lymph nodes, how are the T cells distributed in non-follicular regions?

A

parafollicular zone

22
Q

what is the medulla of the lymph nodes composed of?

A

cords and sinuses

23
Q

list the path lymph filters through lymph nodes

A

outer regions of lymph nodes -> medulla -> efferent lymph vessels

24
Q

what is the purpose of the spleen?

A

site where all RBCs that reach the end of their lifespan are recycled

25
Q

true or false: the spleen has a cortex and medulla

A

false

26
Q

true or false: the spleen has follicles (made of B lymphocytes) that are evenly distributed in the spleen

A

true

27
Q

Splenic blood vessels are encapsulated by ______________ and form “____________________”.

A

T lymphocytes,
periarteriolar lymphatic sheaths or PALS

28
Q

what does the central arteriole divide and give rise to?

A

penicillar arterioles

29
Q

list the flow of blood in the spleen

A

arteries -> central arteriole -> penicillar arteriole -> sinusoidal capillaries -> splenic venules and veins

30
Q

in the splenic sinuses, what digest the RBCs and recycle iron?

A

macrophages that sit on splenic cords

31
Q

what is the region of the spleen where lymphocytes are present?

A

white pulp

32
Q

what part of the spleen is of the splenic sinuses where there are RBCs?

A

red pulp

33
Q

what is the lymphocyte aggregation called particularly in the ileum of the small intestine?

A

peyer’s patches

34
Q

what is the lymphocyte aggregation called particularly surrounding larger airways in the lungs?

A

BALT